2024

Routine infant skincare advice in the UK: A cross-sectional survey

Authors: Goldsmith, L. P., Roberts, A., Flohr, C., Boyle, R. J., Ussher, M. & Perkin, M. R., Jan 2024, In: Clinical and Experimental Allergy. 54, 1, p. 56-60 5 p.

Phototherapy for atopic dermatitis: A survey of European practice

Authors: Steyn, M., Gerbens, L. A. A., Spuls, P. I., Mashayekhi, S., Deleuran, M., Barbarot, S., Wollenberg, A., Ferguson, J., Ibbotson, S. & Flohr, C., Mar 2024, In: Journal of the European Academy of Dermatology and Venereology. 38, 3, p. 521-529 9 p.

Mind and skin: Exploring the links between inflammation, sleep disturbance and neurocognitive function in patients with atopic dermatitis

Authors: Cameron, S., Donnelly, A., Broderick, C., Arichi, T., Bartsch, U., Dazzan, P., Elbeling, J., Godfrey, E., Gringras, P., Heathcote, L. C., Joseph, D., Wood, T. C., Pariante, C., Rubia, K. & Flohr, C., Jan 2024, In: Allergy: European Journal of Allergy and Clinical Immunology. 79, 1, p. 26-36 11 p.

Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Authors: GBD 2021 Risk Factors Collaborators, Brauer, M., Roth, G. A., Aravkin, A. Y., Zheng, P., Abate, K. H., Abate, Y. H., Abbafati, C., Abbasgholizadeh, R., Abbasi, M. A., Abbasian, M., Abbasifard, M., Abbasi-Kangevari, M., Abd ElHafeez, S., Abd-Elsalam, S., Abdi, P., Abdollahi, M., Abdoun, M., Abdulah, D. M. & Abdullahi, A. & 31 others, , 18 May 2024, In: Lancet. 403, 10440, p. 2162-2203 42 p.

Executive summary: Consensus treatment guidelines for the use of methotrexate for inflammatory skin disease in pediatric patients

Authors: Brandling-Bennett, H. A., Arkin, L. M., Chiu, Y. E., Hebert, A. A., Callen, J. P., Castelo-Soccio, L., Co, D. O., Cordoro, K. M., Curran, M. L., Dalrymple, A. M., Flohr, C., Gordon, K. B., Hanna, D., Irvine, A. D., Kim, S., Kirkorian, A. Y., Lara-Corrales, I., Lindstrom, J., Paller, A. S. & Reyes, M. & 7 others, , Jun 2024, In: Journal of the American Academy of Dermatology. 90, 6, p. 1271-1275 5 p.

Development of an intervention for reducing infant bathing frequency

Authors: Goldsmith, L. P., Perkin, M. R., Wahlich, C., Chandrasekaran, L., Cornelius, V., Boyle, R. J., Flohr, C., Roberts, A., Willis, K. & Ussher, M., Feb 2024, In: PLoS ONE. 19, 2 FEBRUARY, e0298335.

Comparing binary efficacy outcomes for systemic immunomodulatory treatments for atopic dermatitis in a living systematic review and network meta-Analysis

Authors: Drucker, A. M., Lam, M., Elsawi, R., Prieto-Merino, D., Malek, R., Ellis, A. G., Yiu, Z. Z. N., Rochwerg, B., Di Giorgio, S., Arents, B. W. M., Burton, T., Spuls, P. I., Schmitt, J. & Flohr, C., Feb 2024, In: British Journal of Dermatology. 190, 2, p. 184-190 7 p.

Biomarkers of peanut allergy in children over time

Authors: Foong, R. X., Du Toit, G., van Ree, R., Bahnson, H. T., Radulovic, S., Craven, J., Kwok, M., Jama, Z., Versteeg, S. A., Brough, H. A., Logan, K., Perkin, M. R., Flohr, C., Lack, G. & Santos, A. F., Oct 2024, In: Allergy: European Journal of Allergy and Clinical Immunology. 79, 10, p. 2775-2786 12 p.

The complex role of the chemokine CX3CL1/Fractalkine in major depressive disorder: A narrative review of preclinical and clinical studies

Authors: Bridge, S., Karagiannis, S. N. & Borsini, A., 28 Apr 2024, In: Brain, Behavior, & Immunity - Health. 38, p. 100778 100778.

Protective effects of allergic diseases in COVID-19 outcomes: A retrospective cohort study in UK Biobank in the general population and in patients with cancer

Authors: Santaolalla, A., Bax, H. J., Chauhan, J., Josephs, D. H., Van Hemelrijck, M. & Karagiannis, S. N., Apr 2024, In: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 54, 4, p. 297-299 3 p.

Multiple outcomes of the germline p16INK4a mutation affecting senescence and immunity in human skin

Authors: Subramanian, P., Sayegh, S., Laphanuwat, P., Devine, O. P., Fantecelle, C. H., Sikora, J., Chambers, E. S., Karagiannis, S. N., Gomes, D. C. O., Kulkarni, A., Rustin, M. H. A., Lacy, K. E. & Akbar, A. N., 17 Oct 2024, In: AGING CELL. e14373.

In Vivo PET Imaging of 89Zr-Labeled Natural Killer Cells and the Modulating Effects of a Therapeutic Antibody

Authors: Pham, T., Chenoweth, A., Patel, N., Banu, A., Osborn, G., Blower, P., Karagiannis, S. N. & Ma, M., 1 Jul 2024, In: Journal of Nuclear Medicine. 65, 7, p. 1035-1042 8 p.

IgE glycosylation and impact on structure and function: A systematic review

Authors: McCraw, A. J., Palhares, L. C. G. F., Hendel, J. L., Gardner, R. A., Santaolalla, A., Crescioli, S., McDonnell, J., Van Hemelrijck, M., Chenoweth, A., Spencer, D. I. R., Wagner, G. K. & Karagiannis, S. N., 4 Aug 2024, In: Allergy. 79, 10, p. 2625-2661 37 p.

Granulocytes and mast cells in AllergoOncology-Bridging allergy to cancer: An EAACI position paper

Authors: Pascal, M., Bax, H. J., Bergmann, C., Bianchini, R., Castells, M., Chauhan, J., De Las Vecillas, L., Hartmann, K., Álvarez, E. I., Jappe, U., Jimenez-Rodriguez, T.-W., Knol, E., Levi-Schaffer, F., Mayorga, C., Poli, A., Redegeld, F., Santos, A. F., Jensen-Jarolim, E. & Karagiannis, S. N., Sept 2024, In: Allergy. 79, 9, p. 2319-2345 27 p.

AllergoOncology: Biomarkers and refined classification for research in the allergy and glioma nexus-A joint EAACI-EANO position paper

Authors: Turner, M. C., Radzikowska, U., Ferastraoaru, D. E., Pascal, M., Wesseling, P., McCraw, A., Backes, C., Bax, H. J., Bergmann, C., Bianchini, R., Cari, L., de Las Vecillas, L., Izquierdo, E., Lind-Holm Mogensen, F., Michelucci, A., Nazarov, P. V., Niclou, S. P., Nocentini, G., Ollert, M. & Preusser, M. & 10 others, , Jun 2024, In: Allergy. 79, 6, p. 1419-1439 21 p.

Unravelling drivers of cutaneous squamous cell carcinoma in recessive dystrophic epidermolysis bullosa

Authors: Santucci, C., Alexandru, M., Chen, X., Mellerio, J. E., Karagiannis, S. N. & Jackow, J., 1 May 2024, In: Human Immunology. 85, 3, p. 110805 110805.

Slac2-b Coordinates Extracellular Vesicle Secretion to Regulate Keratinocyte Adhesion and Migration

Authors: Bare, Y., Chan, G. K., Hayday, T., McGrath, J. A. & Parsons, M., 30 Sept 2024, In: Journal of Investigative Dermatology. 141, 3, p. 523-532.e2

Pain in recessive dystrophic epidermolysis bullosa (RDEB): findings of the Prospective Epidermolysis Bullosa Longitudinal Evaluation Study (PEBLES)

Authors: Jeffs, E., Pillay, E. I., Ledwaba-Chapman, L., Bisquera, A., Robertson, S. J., McGrath, J. A., Wang, Y., Martinez, A. E. & Mellerio, J. E., 11 Oct 2024, In: Orphanet Journal of Rare Diseases. 19, 1, p. 375 1 p., 375.

Integrating Porous Silicon Nanoneedles within Medical Devices for Nucleic Acid Nanoinjection

Authors: Wang, C., Gu, C., Popp, C., Vashisth, P., Mustfa, S. A., Martella, D. A., Spiteri, C., McLennan, S., Sun, N., Riddle, M., Eide, C. R., Parsons, M., Tolar, J., McGrath, J. A. & Chiappini, C., 11 Jun 2024, In: ACS Nano. 18, 23, p. 14938-14953 16 p.

Genome-wide meta-analysis implicates variation affecting mast cell biology in urticaria

Authors: McSweeney, S. M., Saklatvala, J., Rispoli, R., Ganier, C., Woszczek, G., Thomas, L., Hveem, K., Løset, M., Dand, N., Tziotzios, C., Simpson, M. & McGrath, J. A., Feb 2024, In: Journal of Allergy and Clinical Immunology. 153, 2, p. 521-526.e11

Costs of UK community care for individuals with recessive dystrophic epidermolysis bullosa: Findings of the Prospective Epidermolysis Bullosa Longitudinal Evaluation Study

Authors: Jeffs, E., Pillay, E., Ledwaba-Chapman, L., Bisquera, A., Robertson, S., McGrath, J., Wang, Y., Martinez, A., Patel, A. & Mellerio, J. E., Feb 2024, In: Skin Health and Disease. 4, 1, e314.

Tumor associated macrophages as key contributors and targets in current and future therapies for melanoma

Authors: Habib, S., Osborn, G., Willsmore, Z., Chew, M. W., Jakubow, S., Fitzpatrick, A., Wu, Y., Sinha, K., Lloyd-Hughes, H., Geh, J. L. C., MacKenzie-Ross, A. D., Whittaker, S., Sanz-Moreno, V., Lacy, K. E., Karagiannis, S. N. & Adams, R., 2024, In: Expert Review Of Clinical Immunology. 20, 8, p. 895-911 17 p.

Chondroitin Sulfate Proteoglycan 4 (CSPG4) as an Emerging Target for Immunotherapy to Treat Melanoma

Authors: Chen, X., Habib, S., Alexandru, M., Chauhan, J., Evan, T., Troka, J. M., Rahimi, A., Esapa, B., Tull, T. J., Ng, W. Z., Fitzpatrick, A., Wu, Y., Geh, J. L. C., Lloyd-Hughes, H., Palhares, L. C. G. F., Adams, R., Bax, H. J., Whittaker, S., Jacków-Malinowska, J. & Karagiannis, S. N., 25 Sept 2024, In: Cancers. 16, 19, 3260.

Accelarated immune ageing is associated with COVID-19 disease severity

Authors: on behalf of the PHOSP-COVID Study collaborative group, ISARIC4C Investigators, Abel, K., Ahmad, S., Ahmed, R., Ali, M., Allen, R. J., Almeida, P., Anderson, D., Armstrong, L., Armstrong, N., Ashworth, M., Ayoub, A., Baggott, R., Bailey, L., Baldwin, D., Ballard, C., Banerjee, A., Bates, A. & Begum, M. & 279 others, , 11 Jan 2024, (E-pub ahead of print) In: Immunity and Ageing. 21, 1, 6.

Inflammatory Memory in Psoriasis: From Remission to Recurrence

Authors: Francis, L., Capon, F., Smith, C. H., Haniffa, M. & Mahil, S. K., 16 May 2024, (E-pub ahead of print) In: Journal of Allergy and Clinical Immunology. 154, 1, p. 42-50 9 p.

Single-cell analysis of psoriasis resolution demonstrates an inflammatory fibroblast state targeted by IL-23 blockade

Authors: Francis, L., McCluskey, D., Ganier, C., Jiang, T., Du-Harpur, X., Gabriel, J., Dhami, P., Kamra, Y., Visvanathan, S., Barker, J., Smith, C. H., Capon, F. & Mahil, S., 30 Jan 2024, In: Nature Communications. 15, 1, 913.

International Consensus Definition and Diagnostic Criteria for Generalized Pustular Psoriasis from the International Psoriasis Council

Authors: Choon, S. E., Van De Kerkhof, P., Gudjonsson, J. E., De La Cruz, C., Barker, J., Morita, A., Romiti, R., Affandi, A. M., Asawanonda, P., Burden, A. D., Gonzalez, C., Marrakchi, S., Mowla, M. R., Okubo, Y., Oon, H. H., Terui, T., Tsai, T. F., Callis-Duffin, K., Fujita, H. & Jo, S. J. & 14 others, , 17 Jul 2024, In: JAMA dermatology. 160, 7, p. 758-768 11 p.

A genome-wide meta-analysis of palmoplantar pustulosis implicates Th2 responses and cigarette smoking in disease pathogenesis

Authors: APRICOT and PLUM study team, Sept 2024, In: Journal of Allergy and Clinical Immunology. 154, 3, p. 657-665.e9

Acceptability of ‘as needed’ biologic therapy in psoriasis: insights from a multi-stakeholder mixed methods study

Authors: Gleeson, D., Naveed, M., Moorhead, L., McAteer, H., Sewell, G., McGuire, A., Weinman, J., Barker, J. N. W. N., Norton, S., Chapman, S. C. E., Smith, C. H. & Mahil, S. K., 1 Aug 2024, In: The British journal of dermatology. 191, 2, p. 243-251 9 p.

2023

The future is now: the Global Atopic Dermatitis Atlas (GADA)

Authors: Arents, B. W. M., van Zuuren, E. J., Hughes, O., Fedorowicz, Z. & Flohr, C., Dec 2023, In: British Journal of Dermatology. 189, 6, p. 761-763 3 p.

Non-biologic systemic treatments for atopic dermatitis: Current state of the art and future directions

Authors: Paolino, A., Alexander, H., Broderick, C. & Flohr, C., May 2023, In: Clinical and Experimental Allergy. 53, 5, p. 495-510 16 p.

Efficacy and Safety of Tralokinumab in Adolescents with Moderate to Severe Atopic Dermatitis: The Phase 3 ECZTRA 6 Randomized Clinical Trial

Authors: Paller, A. S., Flohr, C., Cork, M., Bewley, A., Blauvelt, A., Hong, H. C. H., Imafuku, S., Schuttelaar, M. L. A., Simpson, E. L., Soong, W., Arlert, P., Lophaven, K. W., Kurbasic, A., Soldbro, L., Vest, N. S. & Wollenberg, A., 21 Jun 2023, In: JAMA dermatology. 159, 6, p. 596-605 10 p.

Efficacy and safety of abrocitinib monotherapy in adolescents and adults: a post hoc analysis of the phase 3 JAK1 atopic dermatitis efficacy and safety (JADE) REGIMEN clinical trial

Authors: Flohr, C., Cork, M. J., Ardern-Jones, M. R., Eichenfield, L. F., Barbarot, S., Feeney, C., Rojo, R., Lazariciu, I. & Nesnas, J., 2023, In: JOURNAL OF DERMATOLOGICAL TREATMENT. 34, 1, 2200866.

Dupilumab improves patient-reported symptoms and health-related quality of life in children aged 6–11 years with severe atopic dermatitis

Authors: Flohr, C., Irvine, A. D., Cork, M. J., Simpson, E. L., Wollenberg, A., Deleuran, M., Praestgaard, A., Thomas, R. B. & Rossi, A. B., Aug 2023, In: British Journal of Dermatology. 189, 2, p. 238-240 3 p.

Comparison of real-world treatment outcomes of systemic immunomodulating therapy in atopic dermatitis patients with dark and light skin types

Authors: TREAT NL registry and UK-Irish A-STAR Study Groups, Mar 2023, In: JAAD International. 10, p. 14-24 11 p.

Biomarkers associated with the development of comorbidities in patients with atopic dermatitis: A systematic review

Authors: BIOMAP Consortium, Jan 2023, In: Allergy: European Journal of Allergy and Clinical Immunology. 78, 1, p. 84-120 37 p.

A systematic review of isotretinoin dosing in acne vulgaris

Authors: Daly, A. U., Baptista Gonçalves, R., Lau, E., Bowers, J., Hussaini, N., Charalambides, M., Coumbe, J., Flohr, C. & Layton, A. M., Sept 2023, In: JEADV Clinical Practice. 2, 3, p. 432-449 18 p.

Target Antigen Attributes and Their Contributions to Clinically Approved Antibody-Drug Conjugates (ADCs) in Haematopoietic and Solid Cancers

Authors: Esapa, B., Jiang, J., Cheung, A., Chenoweth, A., Thurston, D. E. & Karagiannis, S. N., 19 Mar 2023, In: Cancers. 15, 6, 37 p., 1845.

Safety and anti-tumour activity of the IgE antibody MOv18 in patients with advanced solid tumours expressing folate receptor-alpha: a phase I trial

Authors: Spicer, J., Basu, B., Montes, A., Banerji, U., Kristeleit, R., Miller, R., Veal, G. J., Corrigan, C. J., Till, S. J., Figini, M., Canevari, S., Barton, C., Jones, P., Mellor, S., Carroll, S., Selkirk, C., Nintos, G., Kwatra, V., Funingana, I.-G. & Doherty, G. & 12 others, , 25 Jul 2023, In: Nature Communications. 14, 1, p. 4180 4180.

Multi-Omic Data Integration and Feature Selection for Survival-based Patient Stratification via Supervised Concrete Autoencoders

Authors: Da Costa Avelar, P., Laddach, R., Karagiannis, S. N., Wu, M. & Tsoka, S., 2023, Lecture Notes in Computer Science.

Drug repurposing and prediction of multiple interaction types via graph embedding

Authors: Amiri Souri, E., Chenoweth, A., Karagiannis, S. N. & Tsoka, S., 17 May 2023, In: BMC Bioinformatics. 24, 1, p. 202

B cell profiles, antibody repertoire and reactivity reveal dysregulated responses with autoimmune features in melanoma

Authors: Crescioli, S., Correa, I., Ng, J., Willsmore, Z. N., Laddach, R., Chenoweth, A., Chauhan, J., Di Meo, A., Stewart, A., Kalliolia, E., Alberts, E., Adams, R., Harris, R. J., Mele, S., Pellizzari, G., Black, A. B. M., Bax, H. J., Cheung, A., Nakamura, M. & Hoffmann, R. M. & 23 others, , 8 Jun 2023, In: Nature Communications. 14, 1, 3378.

Anti-cancer pro-inflammatory effects of an IgE antibody targeting the melanoma-associated antigen chondroitin sulfate proteoglycan 4

Authors: Chauhan, J., Grandits, M., Palhares, L. C. G. F., Mele, S., Nakamura, M., López-Abente, J., Crescioli, S., Laddach, R., Romero-Clavijo, P., Cheung, A., Stavraka, C., Chenoweth, A. M., Sow, H. S., Chiaruttini, G., Gilbert, A. E., Dodev, T., Koers, A., Pellizzari, G., Ilieva, K. M. & Man, F. & 20 others, , 25 Apr 2023, In: Nature Communications. 14, 1, p. 2192

Loss of RhoE function in dermatofibroma promotes disorganized dermal fibroblast extracellular matrix and increased integrin activation

Authors: Endzhievskaya, S., Hsu, C.-K., Yang, H.-S., Huang, H.-Y., Lin, Y.-C., Lee, J. Y. W., Onoufriadis, A., Takeichi, T., Lee, J.Y.-Y., Shaw, T., McGrath, J. & Parsons, M., 10 Feb 2023, In: Journal of Investigative Dermatology. 143, 8, p. 1487-1497.e9

Itch in recessive dystrophic epidermolysis bullosa: findings of PEBLES, a prospective register study

Authors: Mellerio, J. E., Pillay, E. I., Ledwaba-Chapman, L., Bisquera, A., Robertson, S. J., Papanikolaou, M., McGrath, J. A., Wang, Y., Martinez, A. E. & Jeffs, E., 9 Aug 2023, In: Orphanet Journal of Rare Diseases. 18, 1, 235.

Effects of sleep disturbance on dyspnoea and impaired lung function following hospital admission due to COVID-19 in the UK: a prospective multicentre cohort study

Authors: PHOSP-COVID Study Collaborative Group, Chalder, T., Jolley, C. J., Shah, A. M., Man, W. D. C., Jackson, C., Stewart, I. D., Cunningham, P. S., Chalder, T., Harris, V. C., Ho, L. P., Howard, L. S., Jolley, C. J., Jones, M. G., Marks, M., Patel, B., Richardson, M., Rowlands, A. V., Saunders, R. M. & Scott, J. T. & 273 others, , Aug 2023, In: The Lancet Respiratory Medicine. 11, 8, p. 673-684 12 p.

Determinants of recovery from post-COVID-19 dyspnoea: analysis of UK prospective cohorts of hospitalised COVID-19 patients and community-based controls

Authors: PHOSP-COVID Study Collaborative Group, Pfeffer, P. E., Abel, K., Ahmad, S., Ahmed, R., Ali, M., Allen, R. J., Almeida, P., Anderson, D., Armstrong, L., Armstrong, N., Ashworth, M., Ayoub, A., Baggott, R., Bailey, L., Baldwin, D., Ballard, C., Banerjee, A., Bates, A. & Begum, M. & 276 others, , Jun 2023, In: The Lancet Regional Health - Europe. 29, 100635.

The importance of illness severity and multimorbidity in the association between mental health and body weight in psoriasis: Cross-sectional and longitudinal analysis

Authors: Pavlova, N. T., Moss-Morris, R., Smith, C., Carr, E., Rayner, L. & Picariello, F., 19 Apr 2022, In: Skin Health and Disease. 2, 4, 12 p., e117.

Risk of severe COVID-19 outcomes associated with immune-mediated inflammatory diseases and immune-modifying therapies: a nationwide cohort study in the OpenSAFELY platform

Authors: MacKenna, B., Kennedy, N. A., Mehrkar, A., Rowan, A., Galloway, J., Matthewman, J., Mansfield, K. E., Bechman, K., Yates, M., Brown, J., Schultze, A., Norton, S., Walker, A. J., Morton, C. E., Harrison, D., Bhaskaran, K., Rentsch, C. T., Williamson, E., Croker, R. & Bacon, S. & 28 others, , Jul 2022, In: The Lancet Rheumatology. 4, 7, p. e490-e506

Infection profile of immune-modulatory drugs used in autoimmune diseases: Analysis of summary of product characteristic data

Authors: Ziehfreund, S., Tizek, L., Hangel, N., Fritzsche, M. C., Weidinger, S., Smith, C., Bryce, P. J., Greco, D., van den Bogaard, E. H., Flohr, C., Rastrick, J., Eyerich, S., Buyx, A., Conrad, C., Eyerich, K. & Zink, A., Sept 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 9, p. 1467-1476 10 p.

Electronic screening for mental illness in patients with psoriasis

Authors: Bechman, K., Hayes, J. F., Mathewman, J., Henderson, A. D., Adesanya, E. I., Mansfield, K. E., Smith, C. H., Galloway, J. & Langan, S. M., Aug 2023, In: British Journal of Dermatology. 189, 2, p. 246-248 3 p.

Electronic screening for mental illness in patients with psoriasis

Authors: Zuberbier, T., Abdul Latiff, A., Aggelidis, X., Augustin, M., Balan, R. G., Bangert, C., Beck, L., Bieber, T., Bernstein, J. A., Bertolin Colilla, M., Berardi, A., Bedbrook, A., Bindslev-Jensen, C., Bousquet, J., de Bruin-Weller, M., Bruscky, D., Buyuktiryaki, B., Canonica, G. W., Castro, C. & Chanturidze, N. & 30 others, , Sept 2023, In: Clinical and translational allergy. 13, 9, e12299.

A concept for integrated care pathways for atopic dermatitis—A GA2LEN ADCARE initiative

Authors: Zuberbier, T., Abdul Latiff, A., Aggelidis, X., Augustin, M., Balan, R. G., Bangert, C., Beck, L., Bieber, T., Bernstein, J. A., Bertolin Colilla, M., Berardi, A., Bedbrook, A., Bindslev-Jensen, C., Bousquet, J., de Bruin-Weller, M., Bruscky, D., Buyuktiryaki, B., Canonica, G. W., Castro, C. & Chanturidze, N. & 30 others, , Sept 2023, In: Clinical and translational allergy. 13, 9, e12299.

Clinical and epidemiological features of psoriasis exacerbations in children with SARS-CoV-2 infection

Authors: Skrek, S., Di Lernia, V., Beauchet, A., Bursztejn, A. C., Belloni Fortina, A., Lesiak, A., Thomas, J., Brzezinski, P., Topkarci, Z., Murashkin, N., Torres, T., Epishev, R., Chiriac, A., McPherson, T., Akinde, M., Maruani, A., Luna, P. C., Vidaurri de la Cruz, H., Mallet, S. & Leducq, S. & 7 others, , Oct 2023, In: Journal of the European Academy of Dermatology and Venereology. 37, 10, p. e1192-e1195

Nonadherence to systemic immune-modifying therapy in people with psoriasis during the COVID-19 pandemic: findings from a global cross-sectional survey

Authors: PsoProtect study group, 20 Apr 2023, In: The British journal of dermatology. 188, 5, p. 610-617 8 p.

Manuka honey activates the Aryl Hydrocarbon receptor: implications for skin inflammation

Authors: Alangari, A. A., Ashoori, M. D., Alwan, W., Dawe, H., Stockinger, B., Barker, J. N., Wincent, E. & Di Meglio, P., Aug 2023, In: Pharmacological Research. 194, 106848.

Genetic validation of psoriasis phenotyping in UK Biobank supports the utility of self-reported data and composite definitions for large genetic and epidemiological studies

Authors: Saklatvala, J. R., Hanscombe, K. B., Mahil, S. K., Tsoi, L. C., Elder, J. T., Barker, J. N., Simpson, M. A., Smith, C. H. & Dand, N., Aug 2023, In: Journal of Investigative Dermatology. 143, 8, p. 1598-1601.e10

Development of antidrug antibodies against adalimumab maps to variation within the HLA-DR peptide-binding groove

Authors: Biomarkers of Systemic Treatment Outcomes in Psoriasis (BSTOP) Study Group, Tsakok, T., Saklatvala, J., Rispens, T., Loeff, F. C., de Vries, A., Allen, M. H., Barbosa, I. A., Baudry, D., Dasandi, T., Duckworth, M., Meynell, F., Russell, A., Chapman, A., McBride, S., McKenna, K., Perera, G., Ramsay, H., Ramesh, R. & Sands, K. & 10 others, , 22 Feb 2023, In: JCI Insight. 8, 4, e156643.

Comorbidities of Keloid and Hypertrophic Scars Among Participants in UK Biobank: Comorbidities of excessive scarring

Authors: Ung, C. Y., Warwick, A. N., Onoufriadis, A., Barker, J., Parsons, M., McGrath, J., Shaw, T. & Dand, N., 4 Jan 2023, In: JAMA dermatology. 159, 2, p. 172-181 10 p.

Clinical profile of patients with acute generalized pustular psoriasis with and without IL36RN mutations in multi-ethnic Johor Bahru, Malaysia

Authors: Choon, S. E., Tok, P. S. K., Wong, K. W., Lim, Y. T., Nanu, N. M., Barker, J. N. & Capon, F., Aug 2023, In: Experimental Dermatology. 32, 8, p. 1263-1271 9 p.

Characteristics of “Super-Responders” and “Super-Non-Responders” to First Biologic Monotherapy for Psoriasis: A Nested Case-control Study

Authors: BADBIR Study Group, 11 Nov 2023, (E-pub ahead of print) In: The British journal of dermatology.

Are Janus kinase inhibitors an effective treatment for palmoplantar pustulosis? A critically appraised topic

Authors: BADBIR Study Group, 11 Nov 2023, (E-pub ahead of print) In: The British journal of dermatology.

2022

Topical steroid withdrawal syndrome: time to bridge the gap

Authors: Cotter, C., Burton, T., Proctor, A., Moss, C. & Flohr, C., Nov 2022, In: British Journal of Dermatology. 187, 5, p. 780-781 2 p.

Randomized controlled pilot trial with ion-exchange water softeners to prevent eczema (SOFTER trial)

Authors: Jabbar-Lopez, Z. K., Ezzamouri, B., Briley, A., Greenblatt, D., Gurung, N., Chalmers, J. R., Thomas, K. S., Frost, T., Kezic, S., Common, J. E. A., Danby, S., Cork, M. J., Peacock, J. L. & Flohr, C., 1 Mar 2022, In: Clinical and Experimental Allergy. 52, 3, p. 405-415 11 p.

Atopic dermatitis and risk of autoimmune conditions: Population-based cohort study

Authors: de Lusignan, S., Alexander, H., Broderick, C., Dennis, J., McGovern, A., Feeney, C. & Flohr, C., Sept 2022, In: Journal of Allergy and Clinical Immunology. 150, 3, p. 709-713 5 p.

A national audit of oral propranolol for the treatment of infantile haemangiomas

Authors: Cotter, C., Solman, L. & Flohr, C., Jan 2022, In: British Journal of Dermatology. 186, 1, p. 189-191 3 p.

Special Issue “Antibody Engineering for Cancer Immunotherapy”

Authors: Crescioli, S., White, A. L. & Karagiannis, S. N., 15 Apr 2022, In: Antibodies (Basel, Switzerland). 11, 2, 29.

Regulatory B cell repertoire defects predispose lung cancer patients to immune-related toxicity following checkpoint blockade

Authors: Patel, A. J., Willsmore, Z. N., Khan, N., Richter, A., Naidu, B., Drayson, M. T., Papa, S., Cope, A., Karagiannis, S. N., Perucha, E. & Middleton, G. W., 7 Jun 2022, In: Nature Communications. 13, 1, p. 3148 3148.

Novel drug-target interactions via link prediction and network embedding

Authors: Amiri Souri, E., Laddach, R., Karagiannis, S. N., Papageorgiou, L. G. & Tsoka, S., 4 Apr 2022, In: BMC Bioinformatics. 23, 1, 121.

Long-term effects of COVID-19 on cancer patients: the experience from Guy’s Cancer Centre

Authors: Monroy-Iglesias, M. J., Tremble, K., Russell, B., Moss, C., Dolly, S., Sita-Lumsden, A., Cortellini, A., Pinato, D. J., Rigg, A., Karagiannis, S. N. & Hemelrijck, M. V., 29 Sept 2022, (E-pub ahead of print) In: Future Oncology.

Is There a Role for Exercise When Treating Patients with Cancer with Immune Checkpoint Inhibitors? A Scoping Review

Authors: Handford, J., Chen, M., Rai, R., Moss, C. L., Enting, D., Peat, N., Karagiannis, S. N., Van Hemelrijck, M. & Russell, B., Oct 2022, In: Cancers. 14, 20, 5039.

Immune cell-antibody interactions in health and disease

Authors: Karagiannis, S. N. & Arnold, J. N., 22 Jul 2022, In: Clinical and Experimental Immunology. 209, 1, p. 1-3 3 p.

Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes

Authors: McCraw, A., Gardner, R. A., Davies, A. M., Spencer, D. I. R., Grandits, M., Wagner, G. K., McDonnell, J., Karagiannis, S. N., Chenoweth, A. & Crescioli, S., 3 Nov 2022, In: International Journal of Molecular Sciences. 23, 21, 22 p., 13455.

Enriched circulating and tumor-resident TGF-β+ regulatory B cells in patients with melanoma promote FOXP3+ Tregs

Authors: Harris, R. J., Willsmore, Z., Laddach, R., Crescioli, S., Chauhan, J., Cheung, A., Black, A., Geh, J. L. C., MacKenzie Ross, A. D., Healy, C., Tsoka, S., Spicer, J., Lacy, K. E. & Karagiannis, S. N., 28 Jul 2022, In: OncoImmunology. 11, 1, p. 2104426 2104426.

Clinical and Translational Significance of Basophils in Patients with Cancer

Authors: Chauhan, J., Stavraka, C., Grandits, M., Gusmao Ferreira, L. C., Josephs, D., Lacy, K. E., Spicer, J., Bax, H. & Karagiannis, S. N., 27 Jan 2022, In: Cells. 11, 3, 20 p., 438.

CDK Inhibition Primes for Anti-PD-L1 Treatment in Triple-Negative Breast Cancer Models

Authors: Cheung, A., Chenoweth, A. M., Quist, J., Sow, H. S., Malaktou, C., Ferro, R., Hoffmann, R. M., Osborn, G., Sachouli, E., French, E., Marlow, R., Lacy, K. E., Papa, S., Grigoriadis, A. & Karagiannis, S. N., 11 Jul 2022, In: Cancers. 14, 14, 21 p., 3361.

BRAF inhibitors and their immunological effects in malignant melanoma

Authors: Adams, R., Coumbe, J. E. M., Coumbe, B. G. T., Thomas, J., Willsmore, Z., Dimitrievska, M., Yasuzawa-Parker, M., Hoyle, M., Ingar, S., Geh, J., MacKenzie Ross, A., Healy, C., Papa, S., Lacy, K. E. & Karagiannis, S. N., 23 Feb 2022, (E-pub ahead of print) In: Expert Review Of Clinical Immunology. 18, 4, p. 347-362 16 p.

Antibodies as biomarkers for cancer risk: A systematic review

Authors: Monroy-Iglesias, M. J., Crescioli, S., Beckmann, K., Le, N., Karagiannis, S. N., Van Hemelrijck, M. & Santaolalla, A., Jul 2022, In: Clinical and Experimental Immunology. 209, 1, p. 46-63 18 p.

AllergoOncology: Danger signals in Allergology and Oncology: A European Academy of Allergy and Clinical Immunology (EAACI) Position Paper

Authors: Bergmann, C., Poli, A., Agache, I., Bianchini, R., Bax, H. J., Castells, M., Crescioli, S., Dombrowicz, D., Ferastraoaru, D., Fiebiger, E., Gould, H. J., Hartmann, K., Izquierdo, E., Jordakieva, G., Josephs, D. H., Jutel, M., Levi-Schaffer, F., de Las Vecillas, L., Lotze, M. T. & Osborn, G. & 11 others, , Sept 2022, In: Allergy: European Journal of Allergy and Clinical Immunology. 77, 9, p. 2594-2617 24 p.

The associated burden of mental health conditions in alopecia areata: a population-based study in UK primary care

Authors: Macbeth, A. E., Holmes, S., Harries, M., Chiu, W. S., Tziotzios, C., de Lusignan, S., Messenger, A. G. & Thompson, A. R., Jul 2022, In: British Journal of Dermatology. 187, 1, p. 73-81 9 p.

WNT10A variant and severe scoliosis?

Authors: Kantaputra, P., Olsen, B. & McGrath, J. A., May 2022, In: Journal of Dermatology. 49, 5, p. e183-e184

Transcriptomic response of peripheral blood mononuclear cells to secukinumab in an 8-year-old boy with juvenile generalized pustular psoriasis

Authors: Hou, P. C., Aala, W., Lee, Y. R., Guevara, B. E. K., Chen, P. C., McGrath, J. A. & Hsu, C. K., May 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 5, p. e378-e381

Transcriptomic Analysis of Blaschko-Linear Psoriasis Reveals Shared and Distinct Features with Psoriasis Vulgaris

Authors: Onoufriadis, A., Niazi, U., Dimitrakopoulou, K., Reich, J., Ainali, C., Papanikolaou, M., Kesidou, E., Hsu, C. K., Saqi, M., McGrath, J. A. & Reich, K., Feb 2022, In: Journal of Investigative Dermatology. 142, 2, p. 489-493 5 p.

The Past and Future of Rare Skin Disease Research and Therapy

Authors: Onoufriadis, A. & Mcgrath, J. A., Apr 2022, In: Journal of Investigative Dermatology. 142, 4, p. 1010-1014 5 p.

The epidemiology of epidermolysis bullosa in England and Wales: data from the national epidermolysis bullosa database

Authors: Petrof, G., Papanikolaou, M., Martinez, A. E., Mellerio, J. E., McGrath, J. A., Bardhan, A., Harper, N., Heagerty, A., Ogboli, M., Chiswell, C. & Moss, C., May 2022, In: British Journal of Dermatology. 186, 5, p. 843-848 6 p.

Single-cell transcriptomics in human skin research: available technologies, technical considerations and disease applications

Authors: Theocharidis, G., Tekkela, S., Veves, A., McGrath, J. A. & Onoufriadis, A., May 2022, In: Experimental Dermatology. 31, 5, p. 655-673 19 p.

Restoring type VII collagen in skin

Authors: Lwin, S. M. & McGrath, J. A., 13 May 2022, In: Med. 3, 5, p. 273-275 3 p.

Plasma metabolomic profiling reflects the malnourished and chronic inflammatory state in recessive dystrophic epidermolysis bullosa

Authors: Chen, Y. F., Lu, H. C., Hou, P. C., Lin, Y. C., Aala, W., Onoufriadis, A., McGrath, J. A., Chen, Y. L. & Hsu, C. K., Aug 2022, In: Journal of Dermatological Science. 107, 2, p. 82-88 7 p.

P63 targeted deletion under the FOXN1 promoter disrupts pre-and post-natal thymus development, function and maintenance as well as induces severe hair loss

Authors: Stefanski, H. E., Xing, Y., Nicholls, J., Jonart, L., Goren, E., Taylor, P. A., Mills, A. A., Riddle, M., McGrath, J., Tolar, J., Hollander, G. A. & Blazar, B. R., Jan 2022, In: PLoS ONE. 17, 1 1, e0261770.

Mutations in the ribosome biogenesis factor gene LTV1 are linked to LIPHAK syndrome, a novel poikiloderma-like disorder

Authors: Genomics England Research Consortium, 22 Jun 2022, In: Human Molecular Genetics. 31, 12, p. 1970-1978 9 p.

Metabolic syndrome and comorbidities in patients with psoriasis: a community-based case-control study from the Nagahama cohort in Japan

Authors: Endo, Y., Tabara, Y., Kawaguchi, T., Onoufriadis, A., McGrath, J. A., Matsuda, F. & Kabashima, K., Jan 2022, In: European journal of dermatology : EJD. 32, 1, p. 86-93 8 p.

Incontinentia pigmenti in a male infant and a proposed diagnostic algorithm

Authors: Yang, M. C., Lin, Y. C., Huang, C. H., Ko, T. M., Tsai, M. C., Kuo, P. L., Lee, J. Y. Y., McGrath, J. A. & Hsu, C. K., Jul 2022, In: Clinical and Experimental Dermatology. 47, 7, p. 1366-1368 3 p.

Collagen VII maintains proteostasis in dermal fibroblasts by scaffolding TANGO1 cargo

Authors: Cao, Q., Tartaglia, G., Alexander, M., Park, P. H., Poojan, S., Farshchian, M., Fuentes, I., Chen, M., McGrath, J. A., Palisson, F., Salas-Alanis, J. & South, A. P., Aug 2022, In: Matrix Biology. 111, p. 226-244 19 p.

Clinical characteristics of male frontal fibrosing alopecia: a single-centre case series from London, UK

Authors: Rayinda, T., McSweeney, S. M., Dand, N., Fenton, D. A., McGrath, J. A. & Tziotzios, C., Jan 2022, In: British Journal of Dermatology. 186, 1, p. 195-197 3 p.

Autosomal dominant epidermolysis bullosa simplex exacerbated by hyperkeratotic scabies

Authors: Lin, Y. C., Tu, W. T., Hou, P. C., Huang, H. Y., Chen, P. C., Chang, C. H., Lee, J. Y. Y., McGrath, J. A. & Hsu, C. K., Aug 2022, In: Journal of Dermatology. 49, 8, p. e283-e284

Autoinflammatory Keratinization Disease With Hepatitis and Autism Reveals Roles for JAK1 Kinase Hyperactivity in Autoinflammation

Authors: Takeichi, T., Lee, J. Y. W., Okuno, Y., Miyasaka, Y., Murase, Y., Yoshikawa, T., Tanahashi, K., Nishida, E., Okamoto, T., Ito, K., Muro, Y., Sugiura, K., Ohno, T., McGrath, J. A. & Akiyama, M., 3 Jan 2022, In: Frontiers in Immunology. 12, 737747.

A clinician’s guide to omics resources in dermatology

Authors: Doolan, B. J., McGrath, J. A. & Onoufriadis, A., May 2022, In: Clinical and Experimental Dermatology. 47, 5, p. 858-866 9 p.

Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function

Authors: MuTHER Consortium, Jan 2022, In: Nature genetics. 54, 1, p. 18-29 12 p.

Damaging alleles affecting multiple CARD14 domains are associated with palmoplantar pustulosis

Authors: Niaouris, T., Hernandez Cordero, A., Haddad, S., Hassi, K., Benzian Olsson, N., Bugarin Diz, C., Burden, A. D., Cooper, H., Griffiths, C. E., Parslew, R., Pink, A. E., Reynolds, N. J., Wahie, S., Warren, R. B., Wright, A., Simpson, M., Baum, P., Visvanathan, S., Barker, J. N. & Smith, C. H. & 1 others, , 26 Sept 2022, (Accepted/In press) In: Journal of Investigative Dermatology.

Executive summary: The 2022 British Society for Rheumatology guideline for the treatment of psoriatic arthritis with biologic and targeted synthetic DMARDs

Authors: Tucker, L., Allen, A., Chandler, D., Ciurtin, C., Dick, A., Foulkes, A., Gullick, N., Helliwell, P., Jadon, D., Jones, G., Kyle, S., Madhok, V., McHugh, N., Parkinson, A., Raine, T., Siebert, S., Smith, C., Tillett, W. & Coates, L. C., 30 Aug 2022, In: Rheumatology (Oxford, England). 61, 9, p. 3514-3520 7 p.

Drug Survival Associated with Effectiveness and Safety of Treatment with Guselkumab, Ixekizumab, Secukinumab, Ustekinumab, and Adalimumab in Patients with Psoriasis

Authors: Yiu, Z. Z. N., Becher, G., Kirby, B., Laws, P., Reynolds, N. J., Smith, C. H., Warren, R. B. & Griffiths, C. E. M., Oct 2022, In: JAMA dermatology. 158, 10, p. 1131-1141 11 p.

Genome-wide association meta-analysis identifies 29 new acne susceptibility loci

Authors: Mitchell, B. L., Saklatvala, J. R., Dand, N., Hagenbeek, F. A., Li, X., Min, J. L., Thomas, L., Bartels, M., Jan Hottenga, J., Lupton, M. K., Boomsma, D. I., Dong, X., Hveem, K., Løset, M., Martin, N. G., Barker, J. N., Han, J., Smith, C. H., Rentería, M. E. & Simpson, M. A., Dec 2022, In: Nature Communications. 13, 1, 702.

The Impact of Immune-Modifying Treatments for Skin Diseases on the Immune Response to COVID-19 Vaccines: a Narrative Review

Authors: Liew, S. Y., Tree, T., Smith, C. H. & Mahil, S. K., Dec 2022, In: Current Dermatology Reports. 11, 4, p. 263-288 26 p.

Children with psoriasis and COVID-19: factors associated with an unfavourable COVID-19 course, and the impact of infection on disease progression (Chi-PsoCov registry)

Authors: the Groupe de Recherche sur le Psoriasis (GrPso) of the Société Française de Dermatologie, the Groupe de recherche de la Société Française de Dermatologie Pédiatrique (GR SFDP), the PsoProtect study group, the British Society of Paediatric Dermatology (BPSD), and the Società Italiana di Dermatologia Pediatrica (S.I.Der.P.), Nov 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 11, p. 2076-2086 11 p.

Vaccine hesitancy and access to psoriasis care during the COVID-19 pandemic: findings from a global patient-reported cross-sectional survey

Authors: PsoProtect study group, Bechman, K., Cook, E. S., Dand, N., Yiu, Z. Z. N., Tsakok, T., Meynell, F., Coker, B., Vincent, A., Bachelez, H., Barbosa, I., Brown, M. A., Capon, F., Contreras, C. R., De La Cruz, C., Di Meglio, P., Gisondi, P., Jullien, D., Kelly, J. & Lambert, J. & 20 others, , Aug 2022, In: The British journal of dermatology. 187, 2, p. 254-256 3 p.

Single-cell analysis implicates Th17 to Th2 cell plasticity in the pathogenesis of palmoplantar pustulosis

Authors: APRICOT and PLUM study team, Oct 2022, In: Journal of Allergy and Clinical Immunology. 150, 4, p. 882-893 12 p.

Influence of FLG loss-of-function mutations in host–microbe interactions during atopic skin inflammation

Authors: Oláh, P., Szlávicz, E., Kuchner, M., Nemmer, J., Zeeuwen, P., Lefèvre-Utile, A., Fyhrquist, N., Prast-Nielsen, S., Skoog, T., Serra, A., Rodríguez, E., Raap, U., Meller, S., Gyulai, R., Hupé, P., Kere, J., Levi-Schaffer, F., Tsoka, S., Alexander, H. & Nestle, F. O. & 11 others, , Jun 2022, In: Journal of Dermatological Science. 106, 3, p. 132-140 9 p.

Humoral and cellular immunogenicity to a second dose of COVID-19 vaccine BNT162b2 in people receiving methotrexate or targeted immunosuppression: a longitudinal cohort study

Authors: Mahil, S. K., Bechman, K., Raharja, A., Domingo-Vila, C., Baudry, D., Brown, M. A., Cope, A. P., Dasandi, T., Graham, C., Khan, H., Lechmere, T., Malim, M. H., Meynell, F., Pollock, E., Sychowska, K., Barker, J. N., Norton, S., Galloway, J. B., Doores, K. J. & Tree, T. & 1 others, , Jan 2022, In: The Lancet Rheumatology. 4, 1, p. e42-e52

Differences in Clinical Features and Comorbid Burden between HLA-C∗06:02 Carrier Groups in >9,000 People with Psoriasis

Authors: BADBIR & BSTOP Study Groups, Jun 2022, In: Journal of Investigative Dermatology. 142, 6, p. 1617-1628.e10

Comparative Genetic Analysis of Psoriatic Arthritis and Psoriasis for the Discovery of Genetic Risk Factors and Risk Prediction Modeling

Authors: the BADBIR Study Group & the BSTOP study group, Sept 2022, In: Arthritis and Rheumatology. 74, 9, p. 1535-1543 9 p.

Biomarkers of systemic treatment response in people with psoriasis: a scoping review

Authors: Corbett, M., Ramessur, R., Marshall, D., Acencio, M., Ostaszewski, M., Biscaia De Andrade Barbosa, I., Dand, N., Di Meglio, P., Haddad, S., Jensen, A., Koopmann, W., Mahil, S., Rahmatulla, S., Rastrick, J., Saklatvala, J., Weidinger, S., Wright, K., Eyerich, K., Barker, J. & Ndlovu, M. & 3 others, , Oct 2022, In: British Journal of Dermatology. 187, 4, p. 494-506

Biomarkers of disease progression in people with psoriasis: a scoping review

Authors: Ramessur, R., Corbett, M., Marshall, D., Acencio, M., Biscaia De Andrade Barbosa, I., Dand, N., Di Meglio, P., Haddad, S., Jensen, A., Koopmann, W., Mahil, S., Ostaszewski, M., Rahmatulla, S., Rastrick, J., Saklatvala, J., Weidinger, S., Wright, K., Eyerich, K., Ndlovu, M. & Barker, J. & 3 others, , Oct 2022, In: British Journal of Dermatology. 187, 4, p. 481-493 13 p.