Dand, N., Stuart, P. E., Bowes, J., Ellinghaus, D., Nititham, J., Saklatvala, J. R., Teder-Laving, M., Thomas, L. F., Traks, T., Uebe, S., Assmann, G., Baudry, D., Behrens, F., Billi, A. C., Brown, M. A., Burkhardt, H., Capon, F., Chung, R., Curtis, C. J. & Duckworth, M. & 30 others, Ellinghaus, E., FitzGerald, O., Gerdes, S., Griffiths, C. E. M., Gulliver, S., Helliwell, P. S., Ho, P., Hoffmann, P., Holmen, O. L., Huang, Z.-M., Hveem, K., Jadon, D., Köhm, M., Kraus, C., Lamacchia, C., Lee, S. H., Ma, F., Mahil, S. K., McHugh, N., McManus, R., Modalsli, E. H., Nissen, M. J., Nöthen, M., Oji, V., Oksenberg, J. R., Patrick, M. T., Smith, C. H., Di Meglio, P., Barker, J. N. & Simpson, M. A., 28 Feb 2025, In: Nature Communications. 16, 1, p. 2051 1 p., 2051.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Genetic Risk Factors in Childhood Psoriasis

Authors:

Schwarz, C. W., Blegvad, C., Baudry, D., Tosi, I., Lee, S.-H., Chung, R., Tato-Barcia, E., Curtis, C. J., Smith, C. H., Simpson, M. A., Nybo Andersen, A.-M., Barker, J. N., Di Meglio, P., Skov, L. & Dand, N., 19 Feb 2025, (E-pub ahead of print) In: Journal of Investigative Dermatology.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Matrix mechano-sensing at the invasive front induces a cytoskeletal and transcriptional memory supporting metastasis

Authors:

Maiques, O., Sallan, M. C., Laddach, R., Pandya, P., Varela, A., Crosas-Molist, E., Barcelo, J., Courbot, O., Liu, Y., Graziani, V., Arafat, Y., Sewell, J., Rodriguez-Hernandez, I., Fanshawe, B., Jung-Garcia, Y., Imbert, P. R., Grasset, E. M., Albrengues, J., Santacana, M. & Macià, A. & 15 others, Tarragona, J., Matias-Guiu, X., Marti, R. M., Tsoka, S., Gaggioli, C., Orgaz, J. L., Fruhwirth, G. O., Wallberg, F., Betteridge, K., Reyes-Aldasoro, C. C., Haider, S., Braun, A., Karagiannis, S. N., Elosegui-Artola, A. & Sanz-Moreno, V., 14 Feb 2025, In: Nature Communications. 16, 1, p. 1394 1394.

Research output: Contribution to journal › Article › peer-review

Website | Journal

An IgE antibody targeting HER2 identified by clonal selection restricts breast cancer growth via immune-stimulating activities

Authors:

Palhares, L. C. G. F., Grandits, M., Stoker, K., Chauhan, J., Sow, H. S., Fruhwirth, G. O., Tsoka, S., Birtley, J., Partington, L., Wilson, T., Hardaker, E., Karagiannis, S. N., Bax, H. J. & FitzGerald, K., 12 Feb 2025, In: Journal Of Experimental & Clinical Cancer Research. 44, 1, p. 49 49.

Research output: Contribution to journal › Article › peer-review

Website | Journal

The Aryl Hydrocarbon Receptor (AHR): Peacekeeper of the Skin

Authors:

Dawe, H. R. & Di Meglio, P., Feb 2025, In: International Journal of Molecular Sciences. 26, 4, 1618.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Three’s company: Simultaneous trimodal genome engineering using orthologous Cas proteins

Authors:

Three's company: Simultaneous trimodal genome engineering using orthologous Cas proteins

Brooks, I. R. & Jacków-Malinowska, J., 8 Jan 2025, In: Molecular Therapy. 33, 1, p. 9-10 2 p.

Research output: Contribution to journal › Comment/debate › peer-review

Website | Journal

Physiochemical and functional evaluation of the first-in-class anti-cancer IgE antibody drug, MOv18, through process development and good manufacturing practice production

Authors:

Bax, H. J., Chauhan, J., McCraw, A. J., Grandits, M., Stavraka, C., Lentfer, H., Hillyer, T., Carroll, S., Vigor, K., Selkirk, C., Figini, M., Cheeseman, J., Urbanowicz, P. A., Gardner, R. A., Spencer, D. I. R., Westwood, N., Mellor, S., Spicer, J., Josephs, D. H. & Karagiannis, S. N., 2025, In: Mabs. 17, 1, 2451295.

Research output: Contribution to journal › Article › peer-review

Website | Journal

2024

Routine infant skincare advice in the UK: A cross-sectional survey

Authors: Goldsmith, L. P., Roberts, A., Flohr, C., Boyle, R. J., Ussher, M. & Perkin, M. R., Jan 2024, In: Clinical and Experimental Allergy. 54, 1, p. 56-60 5 p.

Website | Journal

Phototherapy for atopic dermatitis: A survey of European practice

Authors: Steyn, M., Gerbens, L. A. A., Spuls, P. I., Mashayekhi, S., Deleuran, M., Barbarot, S., Wollenberg, A., Ferguson, J., Ibbotson, S. & Flohr, C., Mar 2024, In: Journal of the European Academy of Dermatology and Venereology. 38, 3, p. 521-529 9 p.

Website | Journal

Mind and skin: Exploring the links between inflammation, sleep disturbance and neurocognitive function in patients with atopic dermatitis

Authors: Cameron, S., Donnelly, A., Broderick, C., Arichi, T., Bartsch, U., Dazzan, P., Elbeling, J., Godfrey, E., Gringras, P., Heathcote, L. C., Joseph, D., Wood, T. C., Pariante, C., Rubia, K. & Flohr, C., Jan 2024, In: Allergy: European Journal of Allergy and Clinical Immunology. 79, 1, p. 26-36 11 p.

Website | Journal

Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Authors: GBD 2021 Risk Factors Collaborators, Brauer, M., Roth, G. A., Aravkin, A. Y., Zheng, P., Abate, K. H., Abate, Y. H., Abbafati, C., Abbasgholizadeh, R., Abbasi, M. A., Abbasian, M., Abbasifard, M., Abbasi-Kangevari, M., Abd ElHafeez, S., Abd-Elsalam, S., Abdi, P., Abdollahi, M., Abdoun, M., Abdulah, D. M. & Abdullahi, A. & 31 others, , 18 May 2024, In: Lancet. 403, 10440, p. 2162-2203 42 p.

Website | Journal

Executive summary: Consensus treatment guidelines for the use of methotrexate for inflammatory skin disease in pediatric patients

Authors: Brandling-Bennett, H. A., Arkin, L. M., Chiu, Y. E., Hebert, A. A., Callen, J. P., Castelo-Soccio, L., Co, D. O., Cordoro, K. M., Curran, M. L., Dalrymple, A. M., Flohr, C., Gordon, K. B., Hanna, D., Irvine, A. D., Kim, S., Kirkorian, A. Y., Lara-Corrales, I., Lindstrom, J., Paller, A. S. & Reyes, M. & 7 others, , Jun 2024, In: Journal of the American Academy of Dermatology. 90, 6, p. 1271-1275 5 p.

Website | Journal

Development of an intervention for reducing infant bathing frequency

Authors: Goldsmith, L. P., Perkin, M. R., Wahlich, C., Chandrasekaran, L., Cornelius, V., Boyle, R. J., Flohr, C., Roberts, A., Willis, K. & Ussher, M., Feb 2024, In: PLoS ONE. 19, 2 FEBRUARY, e0298335.

Website | Journal

Comparing binary efficacy outcomes for systemic immunomodulatory treatments for atopic dermatitis in a living systematic review and network meta-Analysis

Authors: Drucker, A. M., Lam, M., Elsawi, R., Prieto-Merino, D., Malek, R., Ellis, A. G., Yiu, Z. Z. N., Rochwerg, B., Di Giorgio, S., Arents, B. W. M., Burton, T., Spuls, P. I., Schmitt, J. & Flohr, C., Feb 2024, In: British Journal of Dermatology. 190, 2, p. 184-190 7 p.

Website | Journal | Lay summary

Biomarkers of peanut allergy in children over time

Authors: Foong, R. X., Du Toit, G., van Ree, R., Bahnson, H. T., Radulovic, S., Craven, J., Kwok, M., Jama, Z., Versteeg, S. A., Brough, H. A., Logan, K., Perkin, M. R., Flohr, C., Lack, G. & Santos, A. F., Oct 2024, In: Allergy: European Journal of Allergy and Clinical Immunology. 79, 10, p. 2775-2786 12 p.

Website | Journal

The complex role of the chemokine CX3CL1/Fractalkine in major depressive disorder: A narrative review of preclinical and clinical studies

Authors: Bridge, S., Karagiannis, S. N. & Borsini, A., 28 Apr 2024, In: Brain, Behavior, & Immunity - Health. 38, p. 100778 100778.

Website | Journal

Protective effects of allergic diseases in COVID-19 outcomes: A retrospective cohort study in UK Biobank in the general population and in patients with cancer

Authors: Santaolalla, A., Bax, H. J., Chauhan, J., Josephs, D. H., Van Hemelrijck, M. & Karagiannis, S. N., Apr 2024, In: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 54, 4, p. 297-299 3 p.

Website | Journal

Multiple outcomes of the germline p16INK4a mutation affecting senescence and immunity in human skin

Authors: Subramanian, P., Sayegh, S., Laphanuwat, P., Devine, O. P., Fantecelle, C. H., Sikora, J., Chambers, E. S., Karagiannis, S. N., Gomes, D. C. O., Kulkarni, A., Rustin, M. H. A., Lacy, K. E. & Akbar, A. N., 17 Oct 2024, In: AGING CELL. e14373.

Website | Journal

In Vivo PET Imaging of 89Zr-Labeled Natural Killer Cells and the Modulating Effects of a Therapeutic Antibody

Authors: Pham, T., Chenoweth, A., Patel, N., Banu, A., Osborn, G., Blower, P., Karagiannis, S. N. & Ma, M., 1 Jul 2024, In: Journal of Nuclear Medicine. 65, 7, p. 1035-1042 8 p.

Website | Journal

IgE glycosylation and impact on structure and function: A systematic review

Authors: McCraw, A. J., Palhares, L. C. G. F., Hendel, J. L., Gardner, R. A., Santaolalla, A., Crescioli, S., McDonnell, J., Van Hemelrijck, M., Chenoweth, A., Spencer, D. I. R., Wagner, G. K. & Karagiannis, S. N., 4 Aug 2024, In: Allergy. 79, 10, p. 2625-2661 37 p.

Website | Journal

Granulocytes and mast cells in AllergoOncology-Bridging allergy to cancer: An EAACI position paper

Authors: Pascal, M., Bax, H. J., Bergmann, C., Bianchini, R., Castells, M., Chauhan, J., De Las Vecillas, L., Hartmann, K., Álvarez, E. I., Jappe, U., Jimenez-Rodriguez, T.-W., Knol, E., Levi-Schaffer, F., Mayorga, C., Poli, A., Redegeld, F., Santos, A. F., Jensen-Jarolim, E. & Karagiannis, S. N., Sept 2024, In: Allergy. 79, 9, p. 2319-2345 27 p.

Website | Journal

AllergoOncology: Biomarkers and refined classification for research in the allergy and glioma nexus-A joint EAACI-EANO position paper

Authors: Turner, M. C., Radzikowska, U., Ferastraoaru, D. E., Pascal, M., Wesseling, P., McCraw, A., Backes, C., Bax, H. J., Bergmann, C., Bianchini, R., Cari, L., de Las Vecillas, L., Izquierdo, E., Lind-Holm Mogensen, F., Michelucci, A., Nazarov, P. V., Niclou, S. P., Nocentini, G., Ollert, M. & Preusser, M. & 10 others, , Jun 2024, In: Allergy. 79, 6, p. 1419-1439 21 p.

Website | Journal

Unravelling drivers of cutaneous squamous cell carcinoma in recessive dystrophic epidermolysis bullosa

Authors: Santucci, C., Alexandru, M., Chen, X., Mellerio, J. E., Karagiannis, S. N. & Jackow, J., 1 May 2024, In: Human Immunology. 85, 3, p. 110805 110805.

Website | Journal

Slac2-b Coordinates Extracellular Vesicle Secretion to Regulate Keratinocyte Adhesion and Migration

Authors: Bare, Y., Chan, G. K., Hayday, T., McGrath, J. A. & Parsons, M., 30 Sept 2024, In: Journal of Investigative Dermatology. 141, 3, p. 523-532.e2

Website | Journal

Pain in recessive dystrophic epidermolysis bullosa (RDEB): findings of the Prospective Epidermolysis Bullosa Longitudinal Evaluation Study (PEBLES)

Authors: Jeffs, E., Pillay, E. I., Ledwaba-Chapman, L., Bisquera, A., Robertson, S. J., McGrath, J. A., Wang, Y., Martinez, A. E. & Mellerio, J. E., 11 Oct 2024, In: Orphanet Journal of Rare Diseases. 19, 1, p. 375 1 p., 375.

Website | Journal

Integrating Porous Silicon Nanoneedles within Medical Devices for Nucleic Acid Nanoinjection

Authors: Wang, C., Gu, C., Popp, C., Vashisth, P., Mustfa, S. A., Martella, D. A., Spiteri, C., McLennan, S., Sun, N., Riddle, M., Eide, C. R., Parsons, M., Tolar, J., McGrath, J. A. & Chiappini, C., 11 Jun 2024, In: ACS Nano. 18, 23, p. 14938-14953 16 p.

Website | Journal

Genome-wide meta-analysis implicates variation affecting mast cell biology in urticaria

Authors: McSweeney, S. M., Saklatvala, J., Rispoli, R., Ganier, C., Woszczek, G., Thomas, L., Hveem, K., Løset, M., Dand, N., Tziotzios, C., Simpson, M. & McGrath, J. A., Feb 2024, In: Journal of Allergy and Clinical Immunology. 153, 2, p. 521-526.e11

Website | Journal

Costs of UK community care for individuals with recessive dystrophic epidermolysis bullosa: Findings of the Prospective Epidermolysis Bullosa Longitudinal Evaluation Study

Authors: Jeffs, E., Pillay, E., Ledwaba-Chapman, L., Bisquera, A., Robertson, S., McGrath, J., Wang, Y., Martinez, A., Patel, A. & Mellerio, J. E., Feb 2024, In: Skin Health and Disease. 4, 1, e314.

Website | Journal

Tumor associated macrophages as key contributors and targets in current and future therapies for melanoma

Authors: Habib, S., Osborn, G., Willsmore, Z., Chew, M. W., Jakubow, S., Fitzpatrick, A., Wu, Y., Sinha, K., Lloyd-Hughes, H., Geh, J. L. C., MacKenzie-Ross, A. D., Whittaker, S., Sanz-Moreno, V., Lacy, K. E., Karagiannis, S. N. & Adams, R., 2024, In: Expert Review Of Clinical Immunology. 20, 8, p. 895-911 17 p.

Website | Journal

Chondroitin Sulfate Proteoglycan 4 (CSPG4) as an Emerging Target for Immunotherapy to Treat Melanoma

Authors: Chen, X., Habib, S., Alexandru, M., Chauhan, J., Evan, T., Troka, J. M., Rahimi, A., Esapa, B., Tull, T. J., Ng, W. Z., Fitzpatrick, A., Wu, Y., Geh, J. L. C., Lloyd-Hughes, H., Palhares, L. C. G. F., Adams, R., Bax, H. J., Whittaker, S., Jacków-Malinowska, J. & Karagiannis, S. N., 25 Sept 2024, In: Cancers. 16, 19, 3260.

Website | Journal | Lay summary

Accelarated immune ageing is associated with COVID-19 disease severity

Authors: on behalf of the PHOSP-COVID Study collaborative group, ISARIC4C Investigators, Abel, K., Ahmad, S., Ahmed, R., Ali, M., Allen, R. J., Almeida, P., Anderson, D., Armstrong, L., Armstrong, N., Ashworth, M., Ayoub, A., Baggott, R., Bailey, L., Baldwin, D., Ballard, C., Banerjee, A., Bates, A. & Begum, M. & 279 others, , 11 Jan 2024, (E-pub ahead of print) In: Immunity and Ageing. 21, 1, 6.

Website | Journal

Inflammatory Memory in Psoriasis: From Remission to Recurrence

Authors: Francis, L., Capon, F., Smith, C. H., Haniffa, M. & Mahil, S. K., 16 May 2024, (E-pub ahead of print) In: Journal of Allergy and Clinical Immunology. 154, 1, p. 42-50 9 p.

Website | Journal

Single-cell analysis of psoriasis resolution demonstrates an inflammatory fibroblast state targeted by IL-23 blockade

Authors: Francis, L., McCluskey, D., Ganier, C., Jiang, T., Du-Harpur, X., Gabriel, J., Dhami, P., Kamra, Y., Visvanathan, S., Barker, J., Smith, C. H., Capon, F. & Mahil, S., 30 Jan 2024, In: Nature Communications. 15, 1, 913.

Website | Journal

International Consensus Definition and Diagnostic Criteria for Generalized Pustular Psoriasis from the International Psoriasis Council

Authors: Choon, S. E., Van De Kerkhof, P., Gudjonsson, J. E., De La Cruz, C., Barker, J., Morita, A., Romiti, R., Affandi, A. M., Asawanonda, P., Burden, A. D., Gonzalez, C., Marrakchi, S., Mowla, M. R., Okubo, Y., Oon, H. H., Terui, T., Tsai, T. F., Callis-Duffin, K., Fujita, H. & Jo, S. J. & 14 others, , 17 Jul 2024, In: JAMA dermatology. 160, 7, p. 758-768 11 p.

Website | Journal

A genome-wide meta-analysis of palmoplantar pustulosis implicates Th2 responses and cigarette smoking in disease pathogenesis

Authors: APRICOT and PLUM study team, Sept 2024, In: Journal of Allergy and Clinical Immunology. 154, 3, p. 657-665.e9

Website | Journal

Acceptability of ‘as needed’ biologic therapy in psoriasis: insights from a multi-stakeholder mixed methods study

Authors: Gleeson, D., Naveed, M., Moorhead, L., McAteer, H., Sewell, G., McGuire, A., Weinman, J., Barker, J. N. W. N., Norton, S., Chapman, S. C. E., Smith, C. H. & Mahil, S. K., 1 Aug 2024, In: The British journal of dermatology. 191, 2, p. 243-251 9 p.

Website | Journal | Lay summary

AllergoOncology: Danger signals in allergology and oncology. A European Academy of Allergy and Clinical Immunology (EAACI) Position Paper

Authors:

AllergoOnkologie: Gefahrensignale in der Allergologie und Onkologie Ein Positionspapier der European Academy of Allergy and Clinical Immunology (EAACI)

Translated title of the contribution: Bergmann, C., Poli, A., Agache, I., Bianchini, R., Bax, H. J., Castells, M., Crescioli, S., Dombrowicz, D., Ferastraoaru, D., Fiebiger, E., Gould, H. J., Hartmann, K., Izquierdo, E., Jordakieva, G., Josephs, D. H., Jutel, M., Levi-Schaffer, F., de las Vecillas, L., Lotze, M. T. & Osborn, G. & 11 others, Pascal, M., Redegeld, F., Rosenstreich, D., Roth-Walter, F., Schmidt-Weber, C. B., Shamji, M., Steveling, E. H., Turner, M. C., Untersmayr, E., Jensen-Jarolim, E. & Karagiannis, S. N., Dec 2024, In: ALLERGOLOGIE. 47, 12, p. 771-801 31 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

A scalable and cGMP-compatible autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa

Authors:

Neumayer, G., Torkelson, J. L., Li, S., McCarthy, K., Zhen, H. H., Vangipuram, M., Mader, M. M., Gebeyehu, G., Jaouni, T. M., Jacków-Malinowska, J., Rami, A., Hansen, C., Guo, Z., Gaddam, S., Tate, K. M., Pappalardo, A., Li, L., Chow, G. M., Roy, K. R. & Nguyen, T. M. & 11 others, Tanabe, K., McGrath, P. S., Cramer, A., Bruckner, A., Bilousova, G., Roop, D., Tang, J. Y., Christiano, A., Steinmetz, L. M., Wernig, M. & Oro, A. E., Dec 2024, In: Nature Communications. 15, 1, 5834.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Multiple outcomes of the germline p16^INK4a mutation affecting senescence and immunity in human skin

Authors:

Subramanian, P., Sayegh, S., Laphanuwat, P., Devine, O. P., Fantecelle, C. H., Sikora, J., Chambers, E. S., Karagiannis, S. N., Gomes, D. C. O., Kulkarni, A., Rustin, M. H. A., Lacy, K. E. & Akbar, A. N., 17 Oct 2024, In: AGING CELL. e14373.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Lipid Nanoparticles Efficiently Deliver the Base Editor ABE8e for COL7A1 Correction in Dystrophic Epidermolysis Bullosa Fibroblasts In Vitro

Authors:

Guri-Lamce, I., Alrokh, Y., Graham, C., Maeshima, R., Rognoni, E., Caley, M., Łaczmański, Ł., Hart, S. L., McGrath, J. A. & Jacków-Malinowska, J., Oct 2024, In: Journal of Investigative Dermatology. 144, 10, p. 2314-2317.e3

Research output: Contribution to journal › Article › peer-review

Website | Journal

Biomarkers of peanut allergy in children over time

Authors:

Foong, R. X., Du Toit, G., van Ree, R., Bahnson, H. T., Radulovic, S., Craven, J., Kwok, M., Jama, Z., Versteeg, S. A., Brough, H. A., Logan, K., Perkin, M. R., Flohr, C., Lack, G. & Santos, A. F., Oct 2024, In: Allergy: European Journal of Allergy and Clinical Immunology. 79, 10, p. 2775-2786 12 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Chondroitin Sulfate Proteoglycan 4 (CSPG4) as an Emerging Target for Immunotherapy to Treat Melanoma

Authors:

Chen, X., Habib, S., Alexandru, M., Chauhan, J., Evan, T., Troka, J. M., Rahimi, A., Esapa, B., Tull, T. J., Ng, W. Z., Fitzpatrick, A., Wu, Y., Geh, J. L. C., Lloyd-Hughes, H., Palhares, L. C. G. F., Adams, R., Bax, H. J., Whittaker, S., Jacków-Malinowska, J. & Karagiannis, S. N., 25 Sept 2024, In: Cancers. 16, 19, 3260.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Exploring the Link Between Genetic Predictors of Cardiovascular Disease and Psoriasis

Authors:

Ramessur, R., Saklatvala, J., Budu-Aggrey, A., Ostaszewski, M., Möbus, L., Greco, D., Ndlovu, M., Mahil, S. K., Barker, J. N., Brown, S., Paternoster, L., Dand, N., Simpson, M. A. & Smith, C. H., 18 Sept 2024, In: JAMA Cardiology. 9, 11, p. 1009-1017 9 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Granulocytes and mast cells in AllergoOncology-Bridging allergy to cancer: An EAACI position paper

Authors:

Pascal, M., Bax, H. J., Bergmann, C., Bianchini, R., Castells, M., Chauhan, J., De Las Vecillas, L., Hartmann, K., Álvarez, E. I., Jappe, U., Jimenez-Rodriguez, T.-W., Knol, E., Levi-Schaffer, F., Mayorga, C., Poli, A., Redegeld, F., Santos, A. F., Jensen-Jarolim, E. & Karagiannis, S. N., Sept 2024, In: Allergy. 79, 9, p. 2319-2345 27 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

A genome-wide meta-analysis of palmoplantar pustulosis implicates Th2 responses and cigarette smoking in disease pathogenesis

Authors:

APRICOT and PLUM study team, Sept 2024, In: Journal of Allergy and Clinical Immunology. 154, 3, p. 657-665.e9

Research output: Contribution to journal › Article › peer-review

Website | Journal

IgE glycosylation and impact on structure and function: A systematic review

Authors:

McCraw, A. J., Palhares, L. C. G. F., Hendel, J. L., Gardner, R. A., Santaolalla, A., Crescioli, S., McDonnell, J., Van Hemelrijck, M., Chenoweth, A., Spencer, D. I. R., Wagner, G. K. & Karagiannis, S. N., 4 Aug 2024, In: Allergy. 79, 10, p. 2625-2661 37 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Acceptability of ‘as needed’ biologic therapy in psoriasis: insights from a multi-stakeholder mixed methods study

Authors:

Acceptability of 'as needed' biologic therapy in psoriasis: insights from a multi-stakeholder mixed methods study

Gleeson, D., Naveed, M., Moorhead, L., McAteer, H., Sewell, G., McGuire, A., Weinman, J., Barker, J. N. W. N., Norton, S., Chapman, S. C. E., Smith, C. H. & Mahil, S. K., 1 Aug 2024, In: The British journal of dermatology. 191, 2, p. 243-251 9 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

International Consensus Definition and Diagnostic Criteria for Generalized Pustular Psoriasis from the International Psoriasis Council

Authors:

Choon, S. E., Van De Kerkhof, P., Gudjonsson, J. E., De La Cruz, C., Barker, J., Morita, A., Romiti, R., Affandi, A. M., Asawanonda, P., Burden, A. D., Gonzalez, C., Marrakchi, S., Mowla, M. R., Okubo, Y., Oon, H. H., Terui, T., Tsai, T. F., Callis-Duffin, K., Fujita, H. & Jo, S. J. & 14 others, Merola, J., Mrowietz, U., Puig, L., Thaçi, D., Velásquez, M., Augustine, M., El Sayed, M., Navarini, A. A., Pink, A., Prinz, J., Turki, H., Magalhães, R., Capon, F. & Bachelez, H., 17 Jul 2024, In: JAMA dermatology. 160, 7, p. 758-768 11 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

In Vivo PET Imaging of 89Zr-Labeled Natural Killer Cells and the Modulating Effects of a Therapeutic Antibody

Authors:

Pham, T., Chenoweth, A., Patel, N., Banu, A., Osborn, G., Blower, P., Karagiannis, S. N. & Ma, M., 1 Jul 2024, In: Journal of Nuclear Medicine. 65, 7, p. 1035-1042 8 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Defining disease severity in atopic dermatitis and psoriasis for the application to biomarker research: an interdisciplinary perspective

Authors:

Ramessur, R., Dand, N., Langan, S. M., Saklatvala, J., Fritzsche, M.-C., Holland, S., Arents, B. W. M., McAteer, H., Proctor, A., McMahon, D., Greenwood, M., Buyx, A. M., Messer, T., Weiler, N., Hicks, A., Hecht, P., Weidinger, S., Ndlovu, M. N., Chengliang, D. & Hübenthal, M. & 10 others, Egeberg, A., Paternoster, L., Skov, L., De Jong, E. M. G. J., Middelkamp-Hup, M. A., Mahil, S. K., Barker, J. N., Flohr, C., Brown, S. J. & Smith, C. H., 20 Jun 2024, In: The British journal of dermatology. 191, 1, p. 14-23 10 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

AllergoOncology: Biomarkers and refined classification for research in the allergy and glioma nexus-A joint EAACI-EANO position paper

Authors:

Turner, M. C., Radzikowska, U., Ferastraoaru, D. E., Pascal, M., Wesseling, P., McCraw, A., Backes, C., Bax, H. J., Bergmann, C., Bianchini, R., Cari, L., de Las Vecillas, L., Izquierdo, E., Lind-Holm Mogensen, F., Michelucci, A., Nazarov, P. V., Niclou, S. P., Nocentini, G., Ollert, M. & Preusser, M. & 10 others, Rohr-Udilova, N., Scafidi, A., Toth, R., Van Hemelrijck, M., Weller, M., Jappe, U., Escribese, M. M., Jensen-Jarolim, E., Karagiannis, S. N. & Poli, A., Jun 2024, In: Allergy. 79, 6, p. 1419-1439 21 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Authors:

GBD 2021 Risk Factors Collaborators, Brauer, M., Roth, G. A., Aravkin, A. Y., Zheng, P., Abate, K. H., Abate, Y. H., Abbafati, C., Abbasgholizadeh, R., Abbasi, M. A., Abbasian, M., Abbasifard, M., Abbasi-Kangevari, M., Abd ElHafeez, S., Abd-Elsalam, S., Abdi, P., Abdollahi, M., Abdoun, M., Abdulah, D. M. & Abdullahi, A. & 31 others, Abebe, M., Abedi, A., Abedi, A., Abegaz, T. M., Abeldaño Zuñiga, R. A., Abiodun, O., Abiso, T. L., Aboagye, R. G., Abolhassani, H., Abouzid, M., Aboye, G. B., Abreu, L. G., Abualruz, H., Abubakar, B., Abu-Gharbieh, E., Abukhadijah, H. J. J., Aburuz, S., Abu-Zaid, A., Adane, M. M., Addo, I. Y., Addolorato, G., Adedoyin, R. A., Aden, B., Adetunji, J. B., Adeyeoluwa, T. E., Adha, R., Bernabe, E., Flohr, C., Mazidi, M., Urso, D. & Wang, Y., 18 May 2024, In: Lancet. 403, 10440, p. 2162-2203 42 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Inflammatory Memory in Psoriasis: From Remission to Recurrence

Authors:

Francis, L., Capon, F., Smith, C. H., Haniffa, M. & Mahil, S. K., 16 May 2024, (E-pub ahead of print) In: Journal of Allergy and Clinical Immunology. 154, 1, p. 42-50 9 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Unravelling drivers of cutaneous squamous cell carcinoma in recessive dystrophic epidermolysis bullosa

Authors:

Santucci, C., Alexandru, M., Chen, X., Mellerio, J. E., Karagiannis, S. N. & Jackow, J., 1 May 2024, In: Human Immunology. 85, 3, p. 110805 110805.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Topical gene editing therapeutics using lipid nanoparticles: ‘gene creams’ for genetic skin diseases?

Authors:

Topical gene editing therapeutics using lipid nanoparticles: 'gene creams' for genetic skin diseases?

Guri-Lamce, I., AlRokh, Y., Kim, Y., Maeshima, R., Graham, C., Hart, S. L., McGrath, J. A. & Jacków-Malinowska, J., May 2024, In: British Journal of Dermatology. 190, 5, p. 617-627 11 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Revolutionising healing: Gene Editing’s breakthrough against sickle cell disease

Authors:

Revolutionising healing: Gene Editing's breakthrough against sickle cell disease

Dimitrievska, M., Bansal, D., Vitale, M., Strouboulis, J., Miccio, A., Nicolaides, K. H., El Hoss, S., Shangaris, P. & Jacków-Malinowska, J., May 2024, In: Blood Reviews. 65, p. 101185 101185.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

The complex role of the chemokine CX3CL1/Fractalkine in major depressive disorder: A narrative review of preclinical and clinical studies

Authors:

Bridge, S., Karagiannis, S. N. & Borsini, A., 28 Apr 2024, In: Brain, Behavior, & Immunity - Health. 38, p. 100778 100778.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Protective effects of allergic diseases in COVID-19 outcomes: A retrospective cohort study in UK Biobank in the general population and in patients with cancer

Authors:

Santaolalla, A., Bax, H. J., Chauhan, J., Josephs, D. H., Van Hemelrijck, M. & Karagiannis, S. N., Apr 2024, In: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 54, 4, p. 297-299 3 p.

Research output: Contribution to journal › Letter › peer-review

Website | Journal

Highly efficient biallelic correction of homozygous COL7A1 mutation using ABE8e adenine base editor

Authors:

Brooks, I. R., Alrokh, Y., Kazemizadeh, A., Balon, K., Newby, G., Liu, D. R., Łaczmański, Ł., McGrath, J. A. & Jacków-Malinowska, J., Apr 2024, In: British Journal of Dermatology. 190, 4, p. 583-585 3 p.

Research output: Contribution to journal › Letter › peer-review

Website | Journal

Advanced gene-editing strategy for epidermolysis bullosa simplex

Authors:

Sheriff, A. & Jacków-Malinowska, J., 7 Feb 2024, In: Molecular Therapy. 32, 2, p. 271-272 2 p.

Research output: Contribution to journal › Comment/debate › peer-review

Website | Journal

Single-cell analysis of psoriasis resolution demonstrates an inflammatory fibroblast state targeted by IL-23 blockade

Authors:

Francis, L., McCluskey, D., Ganier, C., Jiang, T., Du-Harpur, X., Gabriel, J., Dhami, P., Kamra, Y., Visvanathan, S., Barker, J., Smith, C. H., Capon, F. & Mahil, S., 30 Jan 2024, In: Nature Communications. 15, 1, 913.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Tumor associated macrophages as key contributors and targets in current and future therapies for melanoma

Authors:

Habib, S., Osborn, G., Willsmore, Z., Chew, M. W., Jakubow, S., Fitzpatrick, A., Wu, Y., Sinha, K., Lloyd-Hughes, H., Geh, J. L. C., MacKenzie-Ross, A. D., Whittaker, S., Sanz-Moreno, V., Lacy, K. E., Karagiannis, S. N. & Adams, R., 2024, In: Expert Review Of Clinical Immunology. 20, 8, p. 895-911 17 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

The role of the skin barrier in food allergy prevention

Authors:

Fay, E., Jones, S., Santos, A. F. & Flohr, C., 1 Jan 2024, Encyclopedia of Food Allergy. Elsevier, p. V3:404-V3:416

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Website | Journal

2023

The future is now: the Global Atopic Dermatitis Atlas (GADA)

Authors: Arents, B. W. M., van Zuuren, E. J., Hughes, O., Fedorowicz, Z. & Flohr, C., Dec 2023, In: British Journal of Dermatology. 189, 6, p. 761-763 3 p.

Website | Journal

Non-biologic systemic treatments for atopic dermatitis: Current state of the art and future directions

Authors: Paolino, A., Alexander, H., Broderick, C. & Flohr, C., May 2023, In: Clinical and Experimental Allergy. 53, 5, p. 495-510 16 p.

Website | Journal

Efficacy and Safety of Tralokinumab in Adolescents with Moderate to Severe Atopic Dermatitis: The Phase 3 ECZTRA 6 Randomized Clinical Trial

Authors: Paller, A. S., Flohr, C., Cork, M., Bewley, A., Blauvelt, A., Hong, H. C. H., Imafuku, S., Schuttelaar, M. L. A., Simpson, E. L., Soong, W., Arlert, P., Lophaven, K. W., Kurbasic, A., Soldbro, L., Vest, N. S. & Wollenberg, A., 21 Jun 2023, In: JAMA dermatology. 159, 6, p. 596-605 10 p.

Website | Journal

Efficacy and safety of ciclosporin versus methotrexate in the treatment of severe atopic dermatitis in children and young people (TREAT): A multicentre parallel group assessor-blinded clinical trial

Authors: on behalf of the TREAT Trial Investigators, Dec 2023, In: British Journal of Dermatology. 189, 6, p. 674-684 11 p.

Website | Journal | Lay summary

Efficacy and safety of abrocitinib monotherapy in adolescents and adults: a post hoc analysis of the phase 3 JAK1 atopic dermatitis efficacy and safety (JADE) REGIMEN clinical trial

Authors: Flohr, C., Cork, M. J., Ardern-Jones, M. R., Eichenfield, L. F., Barbarot, S., Feeney, C., Rojo, R., Lazariciu, I. & Nesnas, J., 2023, In: JOURNAL OF DERMATOLOGICAL TREATMENT. 34, 1, 2200866.

Website | Journal

Dupilumab improves patient-reported symptoms and health-related quality of life in children aged 6–11 years with severe atopic dermatitis

Authors: Flohr, C., Irvine, A. D., Cork, M. J., Simpson, E. L., Wollenberg, A., Deleuran, M., Praestgaard, A., Thomas, R. B. & Rossi, A. B., Aug 2023, In: British Journal of Dermatology. 189, 2, p. 238-240 3 p.

Website | Journal | Lay summary

Comparison of real-world treatment outcomes of systemic immunomodulating therapy in atopic dermatitis patients with dark and light skin types

Authors: TREAT NL registry and UK-Irish A-STAR Study Groups, Mar 2023, In: JAAD International. 10, p. 14-24 11 p.

Website | Journal

Biomarkers associated with the development of comorbidities in patients with atopic dermatitis: A systematic review

Authors: BIOMAP Consortium, Jan 2023, In: Allergy: European Journal of Allergy and Clinical Immunology. 78, 1, p. 84-120 37 p.

Website | Journal

A systematic review of isotretinoin dosing in acne vulgaris

Authors: Daly, A. U., Baptista Gonçalves, R., Lau, E., Bowers, J., Hussaini, N., Charalambides, M., Coumbe, J., Flohr, C. & Layton, A. M., Sept 2023, In: JEADV Clinical Practice. 2, 3, p. 432-449 18 p.

Website | Journal

Target Antigen Attributes and Their Contributions to Clinically Approved Antibody-Drug Conjugates (ADCs) in Haematopoietic and Solid Cancers

Authors: Esapa, B., Jiang, J., Cheung, A., Chenoweth, A., Thurston, D. E. & Karagiannis, S. N., 19 Mar 2023, In: Cancers. 15, 6, 37 p., 1845.

Website | Journal

Safety and anti-tumour activity of the IgE antibody MOv18 in patients with advanced solid tumours expressing folate receptor-alpha: a phase I trial

Authors: Spicer, J., Basu, B., Montes, A., Banerji, U., Kristeleit, R., Miller, R., Veal, G. J., Corrigan, C. J., Till, S. J., Figini, M., Canevari, S., Barton, C., Jones, P., Mellor, S., Carroll, S., Selkirk, C., Nintos, G., Kwatra, V., Funingana, I.-G. & Doherty, G. & 12 others, , 25 Jul 2023, In: Nature Communications. 14, 1, p. 4180 4180.

Website | Journal

Multi-Omic Data Integration and Feature Selection for Survival-based Patient Stratification via Supervised Concrete Autoencoders

Authors: Da Costa Avelar, P., Laddach, R., Karagiannis, S. N., Wu, M. & Tsoka, S., 2023, Lecture Notes in Computer Science.

Website | Journal

Drug repurposing and prediction of multiple interaction types via graph embedding

Authors: Amiri Souri, E., Chenoweth, A., Karagiannis, S. N. & Tsoka, S., 17 May 2023, In: BMC Bioinformatics. 24, 1, p. 202

Website | Journal

B cell profiles, antibody repertoire and reactivity reveal dysregulated responses with autoimmune features in melanoma

Authors: Crescioli, S., Correa, I., Ng, J., Willsmore, Z. N., Laddach, R., Chenoweth, A., Chauhan, J., Di Meo, A., Stewart, A., Kalliolia, E., Alberts, E., Adams, R., Harris, R. J., Mele, S., Pellizzari, G., Black, A. B. M., Bax, H. J., Cheung, A., Nakamura, M. & Hoffmann, R. M. & 23 others, , 8 Jun 2023, In: Nature Communications. 14, 1, 3378.

Website | Journal

Anti-cancer pro-inflammatory effects of an IgE antibody targeting the melanoma-associated antigen chondroitin sulfate proteoglycan 4

Authors: Chauhan, J., Grandits, M., Palhares, L. C. G. F., Mele, S., Nakamura, M., López-Abente, J., Crescioli, S., Laddach, R., Romero-Clavijo, P., Cheung, A., Stavraka, C., Chenoweth, A. M., Sow, H. S., Chiaruttini, G., Gilbert, A. E., Dodev, T., Koers, A., Pellizzari, G., Ilieva, K. M. & Man, F. & 20 others, , 25 Apr 2023, In: Nature Communications. 14, 1, p. 2192

Website | Journal

Loss of RhoE function in dermatofibroma promotes disorganized dermal fibroblast extracellular matrix and increased integrin activation

Authors: Endzhievskaya, S., Hsu, C.-K., Yang, H.-S., Huang, H.-Y., Lin, Y.-C., Lee, J. Y. W., Onoufriadis, A., Takeichi, T., Lee, J.Y.-Y., Shaw, T., McGrath, J. & Parsons, M., 10 Feb 2023, In: Journal of Investigative Dermatology. 143, 8, p. 1487-1497.e9

Website | Journal

Itch in recessive dystrophic epidermolysis bullosa: findings of PEBLES, a prospective register study

Authors: Mellerio, J. E., Pillay, E. I., Ledwaba-Chapman, L., Bisquera, A., Robertson, S. J., Papanikolaou, M., McGrath, J. A., Wang, Y., Martinez, A. E. & Jeffs, E., 9 Aug 2023, In: Orphanet Journal of Rare Diseases. 18, 1, 235.

Website | Journal

Effects of sleep disturbance on dyspnoea and impaired lung function following hospital admission due to COVID-19 in the UK: a prospective multicentre cohort study

Authors: PHOSP-COVID Study Collaborative Group, Chalder, T., Jolley, C. J., Shah, A. M., Man, W. D. C., Jackson, C., Stewart, I. D., Cunningham, P. S., Chalder, T., Harris, V. C., Ho, L. P., Howard, L. S., Jolley, C. J., Jones, M. G., Marks, M., Patel, B., Richardson, M., Rowlands, A. V., Saunders, R. M. & Scott, J. T. & 273 others, , Aug 2023, In: The Lancet Respiratory Medicine. 11, 8, p. 673-684 12 p.

Website | Journal

Determinants of recovery from post-COVID-19 dyspnoea: analysis of UK prospective cohorts of hospitalised COVID-19 patients and community-based controls

Authors: PHOSP-COVID Study Collaborative Group, Pfeffer, P. E., Abel, K., Ahmad, S., Ahmed, R., Ali, M., Allen, R. J., Almeida, P., Anderson, D., Armstrong, L., Armstrong, N., Ashworth, M., Ayoub, A., Baggott, R., Bailey, L., Baldwin, D., Ballard, C., Banerjee, A., Bates, A. & Begum, M. & 276 others, , Jun 2023, In: The Lancet Regional Health - Europe. 29, 100635.

Website | Journal

The importance of illness severity and multimorbidity in the association between mental health and body weight in psoriasis: Cross-sectional and longitudinal analysis

Authors: Pavlova, N. T., Moss-Morris, R., Smith, C., Carr, E., Rayner, L. & Picariello, F., 19 Apr 2022, In: Skin Health and Disease. 2, 4, 12 p., e117.

Website | Journal

Risk of severe COVID-19 outcomes associated with immune-mediated inflammatory diseases and immune-modifying therapies: a nationwide cohort study in the OpenSAFELY platform

Authors: MacKenna, B., Kennedy, N. A., Mehrkar, A., Rowan, A., Galloway, J., Matthewman, J., Mansfield, K. E., Bechman, K., Yates, M., Brown, J., Schultze, A., Norton, S., Walker, A. J., Morton, C. E., Harrison, D., Bhaskaran, K., Rentsch, C. T., Williamson, E., Croker, R. & Bacon, S. & 28 others, , Jul 2022, In: The Lancet Rheumatology. 4, 7, p. e490-e506

Website | Journal

Infection profile of immune-modulatory drugs used in autoimmune diseases: Analysis of summary of product characteristic data

Authors: Ziehfreund, S., Tizek, L., Hangel, N., Fritzsche, M. C., Weidinger, S., Smith, C., Bryce, P. J., Greco, D., van den Bogaard, E. H., Flohr, C., Rastrick, J., Eyerich, S., Buyx, A., Conrad, C., Eyerich, K. & Zink, A., Sept 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 9, p. 1467-1476 10 p.

Website | Journal

Electronic screening for mental illness in patients with psoriasis

Authors: Bechman, K., Hayes, J. F., Mathewman, J., Henderson, A. D., Adesanya, E. I., Mansfield, K. E., Smith, C. H., Galloway, J. & Langan, S. M., Aug 2023, In: British Journal of Dermatology. 189, 2, p. 246-248 3 p.

Website | Journal

Electronic screening for mental illness in patients with psoriasis

Authors: Zuberbier, T., Abdul Latiff, A., Aggelidis, X., Augustin, M., Balan, R. G., Bangert, C., Beck, L., Bieber, T., Bernstein, J. A., Bertolin Colilla, M., Berardi, A., Bedbrook, A., Bindslev-Jensen, C., Bousquet, J., de Bruin-Weller, M., Bruscky, D., Buyuktiryaki, B., Canonica, G. W., Castro, C. & Chanturidze, N. & 30 others, , Sept 2023, In: Clinical and translational allergy. 13, 9, e12299.

Website | Journal

A concept for integrated care pathways for atopic dermatitis—A GA2LEN ADCARE initiative

Website | Journal

Clinical and epidemiological features of psoriasis exacerbations in children with SARS-CoV-2 infection

Authors: Skrek, S., Di Lernia, V., Beauchet, A., Bursztejn, A. C., Belloni Fortina, A., Lesiak, A., Thomas, J., Brzezinski, P., Topkarci, Z., Murashkin, N., Torres, T., Epishev, R., Chiriac, A., McPherson, T., Akinde, M., Maruani, A., Luna, P. C., Vidaurri de la Cruz, H., Mallet, S. & Leducq, S. & 7 others, , Oct 2023, In: Journal of the European Academy of Dermatology and Venereology. 37, 10, p. e1192-e1195

Website | Journal

Nonadherence to systemic immune-modifying therapy in people with psoriasis during the COVID-19 pandemic: findings from a global cross-sectional survey

Authors: PsoProtect study group, 20 Apr 2023, In: The British journal of dermatology. 188, 5, p. 610-617 8 p.

Website | Journal

Manuka honey activates the Aryl Hydrocarbon receptor: implications for skin inflammation

Authors: Alangari, A. A., Ashoori, M. D., Alwan, W., Dawe, H., Stockinger, B., Barker, J. N., Wincent, E. & Di Meglio, P., Aug 2023, In: Pharmacological Research. 194, 106848.

Website | Journal

Genetic validation of psoriasis phenotyping in UK Biobank supports the utility of self-reported data and composite definitions for large genetic and epidemiological studies

Authors: Saklatvala, J. R., Hanscombe, K. B., Mahil, S. K., Tsoi, L. C., Elder, J. T., Barker, J. N., Simpson, M. A., Smith, C. H. & Dand, N., Aug 2023, In: Journal of Investigative Dermatology. 143, 8, p. 1598-1601.e10

Website | Journal

Development of antidrug antibodies against adalimumab maps to variation within the HLA-DR peptide-binding groove

Authors: Biomarkers of Systemic Treatment Outcomes in Psoriasis (BSTOP) Study Group, Tsakok, T., Saklatvala, J., Rispens, T., Loeff, F. C., de Vries, A., Allen, M. H., Barbosa, I. A., Baudry, D., Dasandi, T., Duckworth, M., Meynell, F., Russell, A., Chapman, A., McBride, S., McKenna, K., Perera, G., Ramsay, H., Ramesh, R. & Sands, K. & 10 others, , 22 Feb 2023, In: JCI Insight. 8, 4, e156643.

Website | Journal

Comorbidities of Keloid and Hypertrophic Scars Among Participants in UK Biobank: Comorbidities of excessive scarring

Authors: Ung, C. Y., Warwick, A. N., Onoufriadis, A., Barker, J., Parsons, M., McGrath, J., Shaw, T. & Dand, N., 4 Jan 2023, In: JAMA dermatology. 159, 2, p. 172-181 10 p.

Website | Journal

Clinical profile of patients with acute generalized pustular psoriasis with and without IL36RN mutations in multi-ethnic Johor Bahru, Malaysia

Authors: Choon, S. E., Tok, P. S. K., Wong, K. W., Lim, Y. T., Nanu, N. M., Barker, J. N. & Capon, F., Aug 2023, In: Experimental Dermatology. 32, 8, p. 1263-1271 9 p.

Website | Journal

Characteristics of “Super-Responders” and “Super-Non-Responders” to First Biologic Monotherapy for Psoriasis: A Nested Case-control Study

Authors: BADBIR Study Group, 11 Nov 2023, (E-pub ahead of print) In: The British journal of dermatology.

Website | Journal

Are Janus kinase inhibitors an effective treatment for palmoplantar pustulosis? A critically appraised topic

Authors: BADBIR Study Group, 11 Nov 2023, (E-pub ahead of print) In: The British journal of dermatology.

Website | Journal

Concentrations of Selected Adipocytokines in the Blood Plasma in Proximal Suspensory Desmopathy of Horses, with a Focus on Their Physical Activity—A Pilot Study

Authors:

Nowicka, B., Torres, A., Polkowska, I., Jackow-Nowicka, J., Przewozny, M. & Jackow-Malinowska, J., 22 Dec 2023, In: International Journal of Molecular Sciences. 25, 1, 205.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Characteristics of “Super-Responders” and “Super-Non-Responders” to First Biologic Monotherapy for Psoriasis: A Nested Case-control Study

Authors:

Characteristics of "Super-Responders" and "Super-Non-Responders" to First Biologic Monotherapy for Psoriasis: A Nested Case-control Study

BADBIR Study Group, 11 Nov 2023, (E-pub ahead of print) In: The British journal of dermatology.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Clinical and epidemiological features of psoriasis exacerbations in children with SARS-CoV-2 infection

Authors:

Skrek, S., Di Lernia, V., Beauchet, A., Bursztejn, A. C., Belloni Fortina, A., Lesiak, A., Thomas, J., Brzezinski, P., Topkarci, Z., Murashkin, N., Torres, T., Epishev, R., Chiriac, A., McPherson, T., Akinde, M., Maruani, A., Luna, P. C., Vidaurri de la Cruz, H., Mallet, S. & Leducq, S. & 7 others, Sergeant, M., Zitouni, J., Mahil, S. K., Smith, C. H., Flohr, C., Bachelez, H. & Mahé, E., Oct 2023, In: Journal of the European Academy of Dermatology and Venereology. 37, 10, p. e1192-e1195

Research output: Contribution to journal › Letter › peer-review

Website | Journal

A concept for integrated care pathways for atopic dermatitis—A GA²LEN ADCARE initiative

Authors:

Zuberbier, T., Abdul Latiff, A., Aggelidis, X., Augustin, M., Balan, R. G., Bangert, C., Beck, L., Bieber, T., Bernstein, J. A., Bertolin Colilla, M., Berardi, A., Bedbrook, A., Bindslev-Jensen, C., Bousquet, J., de Bruin-Weller, M., Bruscky, D., Buyuktiryaki, B., Canonica, G. W., Castro, C. & Chanturidze, N. & 30 others, Chong-Neto, H. J., Chu, C. Y., Chularojanamontri, L., Cork, M., Criado, R. F. J., Barredo, L. C., Custovic, A., Darsow, U., Emurlai, A., de Pablo, A., Del Giacco, S., Girolomoni, G., Deleva Jovanova, T., Deleuran, M., Douladiris, N., Duarte, B., Dubakiene, R., Eller, E., Engel-Yeger, B., Ensina, L. F., Filho, N. R., Flohr, C., Fomina, D., Francuzik, W., Galimberti, M. L., Giménez-Arnau, A. M., Godse, K., Mortz, C. G., Siemens, K. & Smith, C., Sept 2023, In: Clinical and translational allergy. 13, 9, e12299.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Electronic screening for mental illness in patients with psoriasis

Authors:

Bechman, K., Hayes, J. F., Mathewman, J., Henderson, A. D., Adesanya, E. I., Mansfield, K. E., Smith, C. H., Galloway, J. & Langan, S. M., Aug 2023, In: British Journal of Dermatology. 189, 2, p. 246-248 3 p.

Research output: Contribution to journal › Letter › peer-review

Website | Journal

Genetic validation of psoriasis phenotyping in UK Biobank supports the utility of self-reported data and composite definitions for large genetic and epidemiological studies

Authors:

Saklatvala, J. R., Hanscombe, K. B., Mahil, S. K., Tsoi, L. C., Elder, J. T., Barker, J. N., Simpson, M. A., Smith, C. H. & Dand, N., Aug 2023, In: Journal of Investigative Dermatology. 143, 8, p. 1598-1601.e10

Research output: Contribution to journal › Letter › peer-review

Website | Journal

Manuka honey activates the Aryl Hydrocarbon receptor: implications for skin inflammation

Authors:

Alangari, A. A., Ashoori, M. D., Alwan, W., Dawe, H., Stockinger, B., Barker, J. N., Wincent, E. & Di Meglio, P., Aug 2023, In: Pharmacological Research. 194, 106848.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Clinical profile of patients with acute generalized pustular psoriasis with and without IL36RN mutations in multi-ethnic Johor Bahru, Malaysia

Authors:

Choon, S. E., Tok, P. S. K., Wong, K. W., Lim, Y. T., Nanu, N. M., Barker, J. N. & Capon, F., Aug 2023, In: Experimental Dermatology. 32, 8, p. 1263-1271 9 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Safety and anti-tumour activity of the IgE antibody MOv18 in patients with advanced solid tumours expressing folate receptor-alpha: a phase I trial

Authors:

Spicer, J., Basu, B., Montes, A., Banerji, U., Kristeleit, R., Miller, R., Veal, G. J., Corrigan, C. J., Till, S. J., Figini, M., Canevari, S., Barton, C., Jones, P., Mellor, S., Carroll, S., Selkirk, C., Nintos, G., Kwatra, V., Funingana, I.-G. & Doherty, G. & 12 others, Gould, H. J., Pellizzari, G., Nakamura, M., Ilieva, K. M., Khiabany, A., Stavraka, C., Chauhan, J., Gillett, C., Pinder, S., Bax, H. J., Josephs, D. H. & Karagiannis, S. N., 25 Jul 2023, In: Nature Communications. 14, 1, p. 4180 4180.

Research output: Contribution to journal › Article › peer-review

Website | Journal

B cell profiles, antibody repertoire and reactivity reveal dysregulated responses with autoimmune features in melanoma

Authors:

Crescioli, S., Correa, I., Ng, J., Willsmore, Z. N., Laddach, R., Chenoweth, A., Chauhan, J., Di Meo, A., Stewart, A., Kalliolia, E., Alberts, E., Adams, R., Harris, R. J., Mele, S., Pellizzari, G., Black, A. B. M., Bax, H. J., Cheung, A., Nakamura, M. & Hoffmann, R. M. & 23 others, Terranova-Barberio, M., Ali, N., Batruch, I., Soosaipillai, A., Prassas, I., Ulndreaj, A., Chatanaka, M. K., Nuamah, R., Kannambath, S., Dhami, P., Geh, J. L. C., MacKenzie Ross, A. D., Healy, C., Grigoriadis, A., Kipling, D., Karagiannis, P., Dunn-Walters, D. K., Diamandis, E. P., Tsoka, S., Spicer, J., Lacy, K. E., Fraternali, F. & Karagiannis, S. N., 8 Jun 2023, In: Nature Communications. 14, 1, 3378.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Drug repurposing and prediction of multiple interaction types via graph embedding

Authors:

Amiri Souri, E., Chenoweth, A., Karagiannis, S. N. & Tsoka, S., 17 May 2023, In: BMC Bioinformatics. 24, 1, p. 202

Research output: Contribution to journal › Article › peer-review

Website | Journal

Cytosine Deaminase Base Editing to Restore COL7A1 in Dystrophic Epidermolysis Bullosa Human: Murine Skin Model

Authors:

Naso, G., Gkazi, S. A., Georgiadis, C., Jayarajan, V., Jacków, J., Fleck, R., Allison, L., Ogunbiyi, O. K., McGrath, J. A., Ilic, D., Di, W. L., Petrova, A. & Qasim, W., May 2023, In: JID Innovations . 3, 3, 100191.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Anti-cancer pro-inflammatory effects of an IgE antibody targeting the melanoma-associated antigen chondroitin sulfate proteoglycan 4

Authors:

Chauhan, J., Grandits, M., Palhares, L. C. G. F., Mele, S., Nakamura, M., López-Abente, J., Crescioli, S., Laddach, R., Romero-Clavijo, P., Cheung, A., Stavraka, C., Chenoweth, A. M., Sow, H. S., Chiaruttini, G., Gilbert, A. E., Dodev, T., Koers, A., Pellizzari, G., Ilieva, K. M. & Man, F. & 20 others, Ali, N., Hobbs, C., Lombardi, S., Lionarons, D. A., Gould, H. J., Beavil, A. J., Geh, J. L. C., MacKenzie Ross, A. D., Healy, C., Calonje, E., Downward, J., Nestle, F. O., Tsoka, S., Josephs, D. H., Blower, P. J., Karagiannis, P., Lacy, K. E., Spicer, J., Karagiannis, S. N. & Bax, H. J., 25 Apr 2023, In: Nature Communications. 14, 1, p. 2192

Research output: Contribution to journal › Article › peer-review

Website | Journal

Nonadherence to systemic immune-modifying therapy in people with psoriasis during the COVID-19 pandemic: findings from a global cross-sectional survey

Authors:

PsoProtect study group, 20 Apr 2023, In: The British journal of dermatology. 188, 5, p. 610-617 8 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Weller et al., T-independent responses to polysaccharides in humans mobilize marginal zone B cells pre-diversified against gut bacterial antigens[1]

Authors:

Spencer, J., Tull, T. J. & Bemark, M., 1 Apr 2023, In: Immunology Letters. 256-257, p. 66-67 2 p.

Research output: Contribution to journal › Letter › peer-review

Website | Journal

Are Janus kinase inhibitors an effective treatment for palmoplantar pustulosis? A critically appraised topic

Authors:

Gleeson, D., Barker, J. N. W. N., Capon, F., Pink, A. E., Woolf, R. T., Smith, C. H. & Mahil, S. K., Apr 2023, In: The British journal of dermatology. 188, 4, p. 471-473 3 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Target Antigen Attributes and Their Contributions to Clinically Approved Antibody-Drug Conjugates (ADCs) in Haematopoietic and Solid Cancers

Authors:

Esapa, B., Jiang, J., Cheung, A., Chenoweth, A., Thurston, D. E. & Karagiannis, S. N., 19 Mar 2023, In: Cancers. 15, 6, 37 p., 1845.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Development of antidrug antibodies against adalimumab maps to variation within the HLA-DR peptide-binding groove

Authors:

Biomarkers of Systemic Treatment Outcomes in Psoriasis (BSTOP) Study Group, Tsakok, T., Saklatvala, J., Rispens, T., Loeff, F. C., de Vries, A., Allen, M. H., Barbosa, I. A., Baudry, D., Dasandi, T., Duckworth, M., Meynell, F., Russell, A., Chapman, A., McBride, S., McKenna, K., Perera, G., Ramsay, H., Ramesh, R. & Sands, K. & 10 others, Shipman, A., Burden, A. D., Griffiths, C. E., Reynolds, N. J., Warren, R. B., Mahil, S., Barker, J., Dand, N., Smith, C. & Simpson, M. A., 22 Feb 2023, In: JCI Insight. 8, 4, e156643.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Challenges of Gene Editing Therapies for Genodermatoses

Authors:

Brooks, I. R., Sheriff, A., Moran, D., Wang, J. & Jacków, J., Feb 2023, In: International Journal of Molecular Sciences. 24, 3, 2298.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Comorbidities of Keloid and Hypertrophic Scars Among Participants in UK Biobank: Comorbidities of excessive scarring

Authors:

Ung, C. Y., Warwick, A. N., Onoufriadis, A., Barker, J., Parsons, M., McGrath, J., Shaw, T. & Dand, N., 4 Jan 2023, In: JAMA dermatology. 159, 2, p. 172-181 10 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Multi-omic Data Integration and Feature Selection for Survival-Based Patient Stratification via Supervised Concrete Autoencoders

Authors:

da Costa Avelar, P. H., Laddach, R., Karagiannis, S. N., Wu, M. & Tsoka, S., 2023, Machine Learning, Optimization, and Data Science - 8th International Workshop, LOD 2022, Revised Selected Papers. Nicosia, G., Giuffrida, G., Ojha, V., La Malfa, E., La Malfa, G., Pardalos, P., Di Fatta, G. & Umeton, R. (eds.). Springer Science and Business Media Deutschland GmbH, p. 47-61 15 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 13811 LNCS).

Research output: Chapter in Book/Report/Conference proceeding › Conference paper › peer-review

Website | Journal

2022

Topical steroid withdrawal syndrome: time to bridge the gap

Authors: Cotter, C., Burton, T., Proctor, A., Moss, C. & Flohr, C., Nov 2022, In: British Journal of Dermatology. 187, 5, p. 780-781 2 p.

Website | Journal

Randomized controlled pilot trial with ion-exchange water softeners to prevent eczema (SOFTER trial)

Authors: Jabbar-Lopez, Z. K., Ezzamouri, B., Briley, A., Greenblatt, D., Gurung, N., Chalmers, J. R., Thomas, K. S., Frost, T., Kezic, S., Common, J. E. A., Danby, S., Cork, M. J., Peacock, J. L. & Flohr, C., 1 Mar 2022, In: Clinical and Experimental Allergy. 52, 3, p. 405-415 11 p.

Website | Journal

Atopic dermatitis and risk of autoimmune conditions: Population-based cohort study

Authors: de Lusignan, S., Alexander, H., Broderick, C., Dennis, J., McGovern, A., Feeney, C. & Flohr, C., Sept 2022, In: Journal of Allergy and Clinical Immunology. 150, 3, p. 709-713 5 p.

Website | Journal

A national audit of oral propranolol for the treatment of infantile haemangiomas

Authors: Cotter, C., Solman, L. & Flohr, C., Jan 2022, In: British Journal of Dermatology. 186, 1, p. 189-191 3 p.

Website | Journal

Special Issue “Antibody Engineering for Cancer Immunotherapy”

Authors: Crescioli, S., White, A. L. & Karagiannis, S. N., 15 Apr 2022, In: Antibodies (Basel, Switzerland). 11, 2, 29.

Website | Journal

Regulatory B cell repertoire defects predispose lung cancer patients to immune-related toxicity following checkpoint blockade

Authors: Patel, A. J., Willsmore, Z. N., Khan, N., Richter, A., Naidu, B., Drayson, M. T., Papa, S., Cope, A., Karagiannis, S. N., Perucha, E. & Middleton, G. W., 7 Jun 2022, In: Nature Communications. 13, 1, p. 3148 3148.

Website | Journal

Novel drug-target interactions via link prediction and network embedding

Authors: Amiri Souri, E., Laddach, R., Karagiannis, S. N., Papageorgiou, L. G. & Tsoka, S., 4 Apr 2022, In: BMC Bioinformatics. 23, 1, 121.

Website | Journal

Long-term effects of COVID-19 on cancer patients: the experience from Guy’s Cancer Centre

Authors: Monroy-Iglesias, M. J., Tremble, K., Russell, B., Moss, C., Dolly, S., Sita-Lumsden, A., Cortellini, A., Pinato, D. J., Rigg, A., Karagiannis, S. N. & Hemelrijck, M. V., 29 Sept 2022, (E-pub ahead of print) In: Future Oncology.

Website | Journal

Is There a Role for Exercise When Treating Patients with Cancer with Immune Checkpoint Inhibitors? A Scoping Review

Authors: Handford, J., Chen, M., Rai, R., Moss, C. L., Enting, D., Peat, N., Karagiannis, S. N., Van Hemelrijck, M. & Russell, B., Oct 2022, In: Cancers. 14, 20, 5039.

Website | Journal

Immune cell-antibody interactions in health and disease

Authors: Karagiannis, S. N. & Arnold, J. N., 22 Jul 2022, In: Clinical and Experimental Immunology. 209, 1, p. 1-3 3 p.

Website | Journal

Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes

Authors: McCraw, A., Gardner, R. A., Davies, A. M., Spencer, D. I. R., Grandits, M., Wagner, G. K., McDonnell, J., Karagiannis, S. N., Chenoweth, A. & Crescioli, S., 3 Nov 2022, In: International Journal of Molecular Sciences. 23, 21, 22 p., 13455.

Website | Journal

Enriched circulating and tumor-resident TGF-β+ regulatory B cells in patients with melanoma promote FOXP3+ Tregs

Authors: Harris, R. J., Willsmore, Z., Laddach, R., Crescioli, S., Chauhan, J., Cheung, A., Black, A., Geh, J. L. C., MacKenzie Ross, A. D., Healy, C., Tsoka, S., Spicer, J., Lacy, K. E. & Karagiannis, S. N., 28 Jul 2022, In: OncoImmunology. 11, 1, p. 2104426 2104426.

Website | Journal

Clinical and Translational Significance of Basophils in Patients with Cancer

Authors: Chauhan, J., Stavraka, C., Grandits, M., Gusmao Ferreira, L. C., Josephs, D., Lacy, K. E., Spicer, J., Bax, H. & Karagiannis, S. N., 27 Jan 2022, In: Cells. 11, 3, 20 p., 438.

Website | Journal

CDK Inhibition Primes for Anti-PD-L1 Treatment in Triple-Negative Breast Cancer Models

Authors: Cheung, A., Chenoweth, A. M., Quist, J., Sow, H. S., Malaktou, C., Ferro, R., Hoffmann, R. M., Osborn, G., Sachouli, E., French, E., Marlow, R., Lacy, K. E., Papa, S., Grigoriadis, A. & Karagiannis, S. N., 11 Jul 2022, In: Cancers. 14, 14, 21 p., 3361.

Website | Journal

BRAF inhibitors and their immunological effects in malignant melanoma

Authors: Adams, R., Coumbe, J. E. M., Coumbe, B. G. T., Thomas, J., Willsmore, Z., Dimitrievska, M., Yasuzawa-Parker, M., Hoyle, M., Ingar, S., Geh, J., MacKenzie Ross, A., Healy, C., Papa, S., Lacy, K. E. & Karagiannis, S. N., 23 Feb 2022, (E-pub ahead of print) In: Expert Review Of Clinical Immunology. 18, 4, p. 347-362 16 p.

Website | Journal

Antibodies as biomarkers for cancer risk: A systematic review

Authors: Monroy-Iglesias, M. J., Crescioli, S., Beckmann, K., Le, N., Karagiannis, S. N., Van Hemelrijck, M. & Santaolalla, A., Jul 2022, In: Clinical and Experimental Immunology. 209, 1, p. 46-63 18 p.

Website | Journal

AllergoOncology: Danger signals in Allergology and Oncology: A European Academy of Allergy and Clinical Immunology (EAACI) Position Paper

Authors: Bergmann, C., Poli, A., Agache, I., Bianchini, R., Bax, H. J., Castells, M., Crescioli, S., Dombrowicz, D., Ferastraoaru, D., Fiebiger, E., Gould, H. J., Hartmann, K., Izquierdo, E., Jordakieva, G., Josephs, D. H., Jutel, M., Levi-Schaffer, F., de Las Vecillas, L., Lotze, M. T. & Osborn, G. & 11 others, , Sept 2022, In: Allergy: European Journal of Allergy and Clinical Immunology. 77, 9, p. 2594-2617 24 p.

Website | Journal

The associated burden of mental health conditions in alopecia areata: a population-based study in UK primary care

Authors: Macbeth, A. E., Holmes, S., Harries, M., Chiu, W. S., Tziotzios, C., de Lusignan, S., Messenger, A. G. & Thompson, A. R., Jul 2022, In: British Journal of Dermatology. 187, 1, p. 73-81 9 p.

Website | Journal

WNT10A variant and severe scoliosis?

Authors: Kantaputra, P., Olsen, B. & McGrath, J. A., May 2022, In: Journal of Dermatology. 49, 5, p. e183-e184

Website | Journal

Transcriptomic response of peripheral blood mononuclear cells to secukinumab in an 8-year-old boy with juvenile generalized pustular psoriasis

Authors: Hou, P. C., Aala, W., Lee, Y. R., Guevara, B. E. K., Chen, P. C., McGrath, J. A. & Hsu, C. K., May 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 5, p. e378-e381

Website | Journal

Transcriptomic Analysis of Blaschko-Linear Psoriasis Reveals Shared and Distinct Features with Psoriasis Vulgaris

Authors: Onoufriadis, A., Niazi, U., Dimitrakopoulou, K., Reich, J., Ainali, C., Papanikolaou, M., Kesidou, E., Hsu, C. K., Saqi, M., McGrath, J. A. & Reich, K., Feb 2022, In: Journal of Investigative Dermatology. 142, 2, p. 489-493 5 p.

Website | Journal

The Past and Future of Rare Skin Disease Research and Therapy

Authors: Onoufriadis, A. & Mcgrath, J. A., Apr 2022, In: Journal of Investigative Dermatology. 142, 4, p. 1010-1014 5 p.

Website | Journal

The epidemiology of epidermolysis bullosa in England and Wales: data from the national epidermolysis bullosa database

Authors: Petrof, G., Papanikolaou, M., Martinez, A. E., Mellerio, J. E., McGrath, J. A., Bardhan, A., Harper, N., Heagerty, A., Ogboli, M., Chiswell, C. & Moss, C., May 2022, In: British Journal of Dermatology. 186, 5, p. 843-848 6 p.

Website | Journal

Single-cell transcriptomics in human skin research: available technologies, technical considerations and disease applications

Authors: Theocharidis, G., Tekkela, S., Veves, A., McGrath, J. A. & Onoufriadis, A., May 2022, In: Experimental Dermatology. 31, 5, p. 655-673 19 p.

Website | Journal

Restoring type VII collagen in skin

Authors: Lwin, S. M. & McGrath, J. A., 13 May 2022, In: Med. 3, 5, p. 273-275 3 p.

Website | Journal

Plasma metabolomic profiling reflects the malnourished and chronic inflammatory state in recessive dystrophic epidermolysis bullosa

Authors: Chen, Y. F., Lu, H. C., Hou, P. C., Lin, Y. C., Aala, W., Onoufriadis, A., McGrath, J. A., Chen, Y. L. & Hsu, C. K., Aug 2022, In: Journal of Dermatological Science. 107, 2, p. 82-88 7 p.

Website | Journal

P63 targeted deletion under the FOXN1 promoter disrupts pre-and post-natal thymus development, function and maintenance as well as induces severe hair loss

Authors: Stefanski, H. E., Xing, Y., Nicholls, J., Jonart, L., Goren, E., Taylor, P. A., Mills, A. A., Riddle, M., McGrath, J., Tolar, J., Hollander, G. A. & Blazar, B. R., Jan 2022, In: PLoS ONE. 17, 1 1, e0261770.

Website | Journal

Mutations in the ribosome biogenesis factor gene LTV1 are linked to LIPHAK syndrome, a novel poikiloderma-like disorder

Authors: Genomics England Research Consortium, 22 Jun 2022, In: Human Molecular Genetics. 31, 12, p. 1970-1978 9 p.

Website | Journal

Metabolic syndrome and comorbidities in patients with psoriasis: a community-based case-control study from the Nagahama cohort in Japan

Authors: Endo, Y., Tabara, Y., Kawaguchi, T., Onoufriadis, A., McGrath, J. A., Matsuda, F. & Kabashima, K., Jan 2022, In: European journal of dermatology : EJD. 32, 1, p. 86-93 8 p.

Website | Journal

Incontinentia pigmenti in a male infant and a proposed diagnostic algorithm

Authors: Yang, M. C., Lin, Y. C., Huang, C. H., Ko, T. M., Tsai, M. C., Kuo, P. L., Lee, J. Y. Y., McGrath, J. A. & Hsu, C. K., Jul 2022, In: Clinical and Experimental Dermatology. 47, 7, p. 1366-1368 3 p.

Website | Journal

Collagen VII maintains proteostasis in dermal fibroblasts by scaffolding TANGO1 cargo

Authors: Cao, Q., Tartaglia, G., Alexander, M., Park, P. H., Poojan, S., Farshchian, M., Fuentes, I., Chen, M., McGrath, J. A., Palisson, F., Salas-Alanis, J. & South, A. P., Aug 2022, In: Matrix Biology. 111, p. 226-244 19 p.

Website | Journal

Clinical characteristics of male frontal fibrosing alopecia: a single-centre case series from London, UK

Authors: Rayinda, T., McSweeney, S. M., Dand, N., Fenton, D. A., McGrath, J. A. & Tziotzios, C., Jan 2022, In: British Journal of Dermatology. 186, 1, p. 195-197 3 p.

Website | Journal

Autosomal dominant epidermolysis bullosa simplex exacerbated by hyperkeratotic scabies

Authors: Lin, Y. C., Tu, W. T., Hou, P. C., Huang, H. Y., Chen, P. C., Chang, C. H., Lee, J. Y. Y., McGrath, J. A. & Hsu, C. K., Aug 2022, In: Journal of Dermatology. 49, 8, p. e283-e284

Website | Journal

Autoinflammatory Keratinization Disease With Hepatitis and Autism Reveals Roles for JAK1 Kinase Hyperactivity in Autoinflammation

Authors: Takeichi, T., Lee, J. Y. W., Okuno, Y., Miyasaka, Y., Murase, Y., Yoshikawa, T., Tanahashi, K., Nishida, E., Okamoto, T., Ito, K., Muro, Y., Sugiura, K., Ohno, T., McGrath, J. A. & Akiyama, M., 3 Jan 2022, In: Frontiers in Immunology. 12, 737747.

Website | Journal

A clinician’s guide to omics resources in dermatology

Authors: Doolan, B. J., McGrath, J. A. & Onoufriadis, A., May 2022, In: Clinical and Experimental Dermatology. 47, 5, p. 858-866 9 p.

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Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function

Authors: MuTHER Consortium, Jan 2022, In: Nature genetics. 54, 1, p. 18-29 12 p.

Website | Journal

Damaging alleles affecting multiple CARD14 domains are associated with palmoplantar pustulosis

Authors: Niaouris, T., Hernandez Cordero, A., Haddad, S., Hassi, K., Benzian Olsson, N., Bugarin Diz, C., Burden, A. D., Cooper, H., Griffiths, C. E., Parslew, R., Pink, A. E., Reynolds, N. J., Wahie, S., Warren, R. B., Wright, A., Simpson, M., Baum, P., Visvanathan, S., Barker, J. N. & Smith, C. H. & 1 others, , 26 Sept 2022, (Accepted/In press) In: Journal of Investigative Dermatology.

Website | Journal

Executive summary: The 2022 British Society for Rheumatology guideline for the treatment of psoriatic arthritis with biologic and targeted synthetic DMARDs

Authors: Tucker, L., Allen, A., Chandler, D., Ciurtin, C., Dick, A., Foulkes, A., Gullick, N., Helliwell, P., Jadon, D., Jones, G., Kyle, S., Madhok, V., McHugh, N., Parkinson, A., Raine, T., Siebert, S., Smith, C., Tillett, W. & Coates, L. C., 30 Aug 2022, In: Rheumatology (Oxford, England). 61, 9, p. 3514-3520 7 p.

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Drug Survival Associated with Effectiveness and Safety of Treatment with Guselkumab, Ixekizumab, Secukinumab, Ustekinumab, and Adalimumab in Patients with Psoriasis

Authors: Yiu, Z. Z. N., Becher, G., Kirby, B., Laws, P., Reynolds, N. J., Smith, C. H., Warren, R. B. & Griffiths, C. E. M., Oct 2022, In: JAMA dermatology. 158, 10, p. 1131-1141 11 p.

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Genome-wide association meta-analysis identifies 29 new acne susceptibility loci

Authors: Mitchell, B. L., Saklatvala, J. R., Dand, N., Hagenbeek, F. A., Li, X., Min, J. L., Thomas, L., Bartels, M., Jan Hottenga, J., Lupton, M. K., Boomsma, D. I., Dong, X., Hveem, K., Løset, M., Martin, N. G., Barker, J. N., Han, J., Smith, C. H., Rentería, M. E. & Simpson, M. A., Dec 2022, In: Nature Communications. 13, 1, 702.

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The Impact of Immune-Modifying Treatments for Skin Diseases on the Immune Response to COVID-19 Vaccines: a Narrative Review

Authors: Liew, S. Y., Tree, T., Smith, C. H. & Mahil, S. K., Dec 2022, In: Current Dermatology Reports. 11, 4, p. 263-288 26 p.

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Children with psoriasis and COVID-19: factors associated with an unfavourable COVID-19 course, and the impact of infection on disease progression (Chi-PsoCov registry)

Authors: the Groupe de Recherche sur le Psoriasis (GrPso) of the Société Française de Dermatologie, the Groupe de recherche de la Société Française de Dermatologie Pédiatrique (GR SFDP), the PsoProtect study group, the British Society of Paediatric Dermatology (BPSD), and the Società Italiana di Dermatologia Pediatrica (S.I.Der.P.), Nov 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 11, p. 2076-2086 11 p.

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Vaccine hesitancy and access to psoriasis care during the COVID-19 pandemic: findings from a global patient-reported cross-sectional survey

Authors: PsoProtect study group, Bechman, K., Cook, E. S., Dand, N., Yiu, Z. Z. N., Tsakok, T., Meynell, F., Coker, B., Vincent, A., Bachelez, H., Barbosa, I., Brown, M. A., Capon, F., Contreras, C. R., De La Cruz, C., Di Meglio, P., Gisondi, P., Jullien, D., Kelly, J. & Lambert, J. & 20 others, , Aug 2022, In: The British journal of dermatology. 187, 2, p. 254-256 3 p.

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Single-cell analysis implicates Th17 to Th2 cell plasticity in the pathogenesis of palmoplantar pustulosis

Authors: APRICOT and PLUM study team, Oct 2022, In: Journal of Allergy and Clinical Immunology. 150, 4, p. 882-893 12 p.

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Influence of FLG loss-of-function mutations in host–microbe interactions during atopic skin inflammation

Authors: Oláh, P., Szlávicz, E., Kuchner, M., Nemmer, J., Zeeuwen, P., Lefèvre-Utile, A., Fyhrquist, N., Prast-Nielsen, S., Skoog, T., Serra, A., Rodríguez, E., Raap, U., Meller, S., Gyulai, R., Hupé, P., Kere, J., Levi-Schaffer, F., Tsoka, S., Alexander, H. & Nestle, F. O. & 11 others, , Jun 2022, In: Journal of Dermatological Science. 106, 3, p. 132-140 9 p.

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Humoral and cellular immunogenicity to a second dose of COVID-19 vaccine BNT162b2 in people receiving methotrexate or targeted immunosuppression: a longitudinal cohort study

Authors: Mahil, S. K., Bechman, K., Raharja, A., Domingo-Vila, C., Baudry, D., Brown, M. A., Cope, A. P., Dasandi, T., Graham, C., Khan, H., Lechmere, T., Malim, M. H., Meynell, F., Pollock, E., Sychowska, K., Barker, J. N., Norton, S., Galloway, J. B., Doores, K. J. & Tree, T. & 1 others, , Jan 2022, In: The Lancet Rheumatology. 4, 1, p. e42-e52

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Differences in Clinical Features and Comorbid Burden between HLA-C∗06:02 Carrier Groups in >9,000 People with Psoriasis

Authors: BADBIR & BSTOP Study Groups, Jun 2022, In: Journal of Investigative Dermatology. 142, 6, p. 1617-1628.e10

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Comparative Genetic Analysis of Psoriatic Arthritis and Psoriasis for the Discovery of Genetic Risk Factors and Risk Prediction Modeling

Authors: the BADBIR Study Group & the BSTOP study group, Sept 2022, In: Arthritis and Rheumatology. 74, 9, p. 1535-1543 9 p.

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Biomarkers of systemic treatment response in people with psoriasis: a scoping review

Authors: Corbett, M., Ramessur, R., Marshall, D., Acencio, M., Ostaszewski, M., Biscaia De Andrade Barbosa, I., Dand, N., Di Meglio, P., Haddad, S., Jensen, A., Koopmann, W., Mahil, S., Rahmatulla, S., Rastrick, J., Saklatvala, J., Weidinger, S., Wright, K., Eyerich, K., Barker, J. & Ndlovu, M. & 3 others, , Oct 2022, In: British Journal of Dermatology. 187, 4, p. 494-506

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Biomarkers of disease progression in people with psoriasis: a scoping review

Authors: Ramessur, R., Corbett, M., Marshall, D., Acencio, M., Biscaia De Andrade Barbosa, I., Dand, N., Di Meglio, P., Haddad, S., Jensen, A., Koopmann, W., Mahil, S., Ostaszewski, M., Rahmatulla, S., Rastrick, J., Saklatvala, J., Weidinger, S., Wright, K., Eyerich, K., Ndlovu, M. & Barker, J. & 3 others, , Oct 2022, In: British Journal of Dermatology. 187, 4, p. 481-493 13 p.

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ABE8e adenine base editor precisely and efficiently corrects a recurrent COL7A1 nonsense mutation

Authors:

Sheriff, A., Guri, I., Zebrowska, P., Llopis-Hernandez, V., Brooks, I. R., Tekkela, S., Subramaniam, K., Gebrezgabher, R., Naso, G., Petrova, A., Balon, K., Onoufriadis, A., Kujawa, D., Kotulska, M., Newby, G., Łaczmański, Ł., Liu, D. R., McGrath, J. A. & Jacków, J., 16 Dec 2022, In: Scientific Reports. 12, 1, 19643.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Human B cells

Authors:

Spencer, J., Bemark, M. & Tull, T. J., Dec 2022, In: Clinical and Experimental Immunology. 210, 3, p. 199-200 2 p.

Research output: Contribution to journal › Editorial › peer-review

Website | Journal

Human B-cell subset identification and changes in inflammatory diseases

Authors:

Velounias, R. L. & Tull, T. J., Dec 2022, In: Clinical and Experimental Immunology. 210, 3, p. 201-216 16 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

The Impact of Immune-Modifying Treatments for Skin Diseases on the Immune Response to COVID-19 Vaccines: a Narrative Review

Authors:

Liew, S. Y., Tree, T., Smith, C. H. & Mahil, S. K., Dec 2022, In: Current Dermatology Reports. 11, 4, p. 263-288 26 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Genome-wide association meta-analysis identifies 29 new acne susceptibility loci

Authors:

Mitchell, B. L., Saklatvala, J. R., Dand, N., Hagenbeek, F. A., Li, X., Min, J. L., Thomas, L., Bartels, M., Jan Hottenga, J., Lupton, M. K., Boomsma, D. I., Dong, X., Hveem, K., Løset, M., Martin, N. G., Barker, J. N., Han, J., Smith, C. H., Rentería, M. E. & Simpson, M. A., Dec 2022, In: Nature Communications. 13, 1, 702.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Infection profile of immune-modulatory drugs used in autoimmune diseases: Analysis of summary of product characteristic data

Authors:

Dey, M., Bechman, K., Zhao, S., Fragoulis, G. E., Smith, C., Cope, A., Nikiphorou, E., Hyrich, K. L. & Galloway, J., 23 Nov 2022, In: RMD Open. 8, 2, 002621.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes

Authors:

Bax, H., Chauhan, J., Stavraka, C., Santaolalla, A., Osborn, G., Khiabany, A., Grandits, M., Lopez-Abente Muroz, J., Gusmao Ferreira, L. C., Chan Wah Hak, C., Robinson, A., Pope, A., Woodman, N., Naceur-Lombardelli, C., Malas, S., Nakamura, M., Coumbe, J. E. M., Laddach, R., Mele, S. & Crescioli, S. & 16 others, Black, A., Lombardi, S., Canevari, S., Figini, M., Sayasneh, A., Tsoka, S., FitzGerald, K., Gillett, C., Pinder, S., Van Hemelrijck, M., Kristeleit, R., Ghosh, S., Montes, A., Spicer, J., Karagiannis, S. N. & Josephs, D., 19 Nov 2022, (E-pub ahead of print) In: British Journal of Cancer. 128, p. 342-353 12 p., https://doi.org/10.1038/s41416-022-02031-x.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Generation and Characterization of Native and Sialic Acid-Deficient IgE

Authors:

McCraw, A., Gardner, R. A., Davies, A. M., Spencer, D. I. R., Grandits, M., Wagner, G. K., McDonnell, J., Karagiannis, S. N., Chenoweth, A. & Crescioli, S., 3 Nov 2022, In: International Journal of Molecular Sciences. 23, 21, 22 p., 13455.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Infection profile of immune-modulatory drugs used in autoimmune diseases: analysis of summary of product characteristic data

Authors:

Dey, M., Bechman, K., Zhao, S., Fragoulis, G. E., Smith, C., Cope, A., Nikiphorou, E., Hyrich, K. L. & Galloway, J., Nov 2022, In: RMD Open. 8, 2

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Children with psoriasis and COVID-19: factors associated with an unfavourable COVID-19 course, and the impact of infection on disease progression (Chi-PsoCov registry)

Authors:

the Groupe de Recherche sur le Psoriasis (GrPso) of the Société Française de Dermatologie, the Groupe de recherche de la Société Française de Dermatologie Pédiatrique (GR SFDP), the PsoProtect study group, the British Society of Paediatric Dermatology (BPSD), and the Società Italiana di Dermatologia Pediatrica (S.I.Der.P.), Nov 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 11, p. 2076-2086 11 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Infection profile of immune-modulatory drugs used in autoimmune diseases: Analysis of summary of product characteristic data

Authors:

Dey, M., Bechman, K., Zhao, S. S., Fragoulis, G. E., Smith, C. H., Cope, A., Nikiphorou, E., Hyrich, K. L. & Galloway, J., 10 Oct 2022, (Accepted/In press) In: RMD Open.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Influencing tumor-associated macrophages in malignant melanoma with monoclonal antibodies

Authors:

Adams, R., Osborn, G., Mukhia, B., Laddach, R., Willsmore, Z., Chenoweth, A., Geh, J. L. C., MacKenzie Ross, A. D., Healy, C., Barber, L., Tsoka, S., Sanz-Moreno, V., Lacy, K. E. & Karagiannis, S. N., 3 Oct 2022, In: OncoImmunology. 11, 1, 17 p., 2127284.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Drug Survival Associated with Effectiveness and Safety of Treatment with Guselkumab, Ixekizumab, Secukinumab, Ustekinumab, and Adalimumab in Patients with Psoriasis

Authors:

Yiu, Z. Z. N., Becher, G., Kirby, B., Laws, P., Reynolds, N. J., Smith, C. H., Warren, R. B. & Griffiths, C. E. M., Oct 2022, In: JAMA dermatology. 158, 10, p. 1131-1141 11 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Biomarkers of disease progression in people with psoriasis: a scoping review

Authors:

Ramessur, R., Corbett, M., Marshall, D., Acencio, M., Biscaia De Andrade Barbosa, I., Dand, N., Di Meglio, P., Haddad, S., Jensen, A., Koopmann, W., Mahil, S., Ostaszewski, M., Rahmatulla, S., Rastrick, J., Saklatvala, J., Weidinger, S., Wright, K., Eyerich, K., Ndlovu, M. & Barker, J. & 3 others, Skov, L., Conrad, C. & Smith, C., Oct 2022, In: British Journal of Dermatology. 187, 4, p. 481-493 13 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Single-cell analysis implicates Th17 to Th2 cell plasticity in the pathogenesis of palmoplantar pustulosis

Authors:

APRICOT and PLUM study team, Oct 2022, In: Journal of Allergy and Clinical Immunology. 150, 4, p. 882-893 12 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Is There a Role for Exercise When Treating Patients with Cancer with Immune Checkpoint Inhibitors? A Scoping Review

Authors:

Handford, J., Chen, M., Rai, R., Moss, C. L., Enting, D., Peat, N., Karagiannis, S. N., Van Hemelrijck, M. & Russell, B., Oct 2022, In: Cancers. 14, 20, 5039.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Biomarkers of systemic treatment response in people with psoriasis: a scoping review

Authors:

BIOMAP Consortium, Corbett, M., Ramessur, R., Marshall, D., Acencio, M. L., Ostaszewski, M., Barbosa, I. A., Dand, N., Di Meglio, P., Haddad, S., Jensen, A. H. M., Koopmann, W., Mahil, S. K., Rahmatulla, S., Rastrick, J., Saklatvala, J., Weidinger, S., Wright, K., Eyerich, K. & Barker, J. N. & 4 others, Ndlovu, M., Conrad, C., Skov, L. & Smith, C. H., Oct 2022, In: British Journal of Dermatology. 187, 4, p. 494-506 13 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Long-term effects of COVID-19 on cancer patients: the experience from Guy’s Cancer Centre

Authors:

Long-term effects of COVID-19 on cancer patients: the experience from Guy's Cancer Centre

Monroy-Iglesias, M. J., Tremble, K., Russell, B., Moss, C., Dolly, S., Sita-Lumsden, A., Cortellini, A., Pinato, D. J., Rigg, A., Karagiannis, S. N. & Hemelrijck, M. V., 29 Sept 2022, (E-pub ahead of print) In: Future Oncology.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Damaging alleles affecting multiple CARD14 domains are associated with palmoplantar pustulosis

Authors:

Niaouris, T., Hernandez Cordero, A., Haddad, S., Hassi, K., Benzian Olsson, N., Bugarin Diz, C., Burden, A. D., Cooper, H., Griffiths, C. E., Parslew, R., Pink, A. E., Reynolds, N. J., Wahie, S., Warren, R. B., Wright, A., Simpson, M., Baum, P., Visvanathan, S., Barker, J. N. & Smith, C. H. & 1 others, Capon, F., 26 Sept 2022, (Accepted/In press) In: Journal of Investigative Dermatology.

Research output: Contribution to journal › Letter › peer-review

Website | Journal

Comparative Genetic Analysis of Psoriatic Arthritis and Psoriasis for the Discovery of Genetic Risk Factors and Risk Prediction Modeling

Authors:

the BADBIR Study Group & the BSTOP study group, Sept 2022, In: Arthritis and Rheumatology. 74, 9, p. 1535-1543 9 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Requirements and expectations of high-quality biomarkers for atopic dermatitis and psoriasis in 2021—a two-round Delphi survey among international experts

Authors:

Ziehfreund, S., Tizek, L., Hangel, N., Fritzsche, M. C., Weidinger, S., Smith, C., Bryce, P. J., Greco, D., van den Bogaard, E. H., Flohr, C., Rastrick, J., Eyerich, S., Buyx, A., Conrad, C., Eyerich, K. & Zink, A., Sept 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 9, p. 1467-1476 10 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

AllergoOncology: Danger signals in Allergology and Oncology: A European Academy of Allergy and Clinical Immunology (EAACI) Position Paper

Authors:

Bergmann, C., Poli, A., Agache, I., Bianchini, R., Bax, H. J., Castells, M., Crescioli, S., Dombrowicz, D., Ferastraoaru, D., Fiebiger, E., Gould, H. J., Hartmann, K., Izquierdo, E., Jordakieva, G., Josephs, D. H., Jutel, M., Levi-Schaffer, F., de Las Vecillas, L., Lotze, M. T. & Osborn, G. & 11 others, Pascal, M., Redegeld, F., Rosenstreich, D., Roth-Walter, F., Schmidt-Weber, C. B., Shamji, M., Steveling, E. H., Turner, M. C., Untersmayr, E., Jensen-Jarolim, E. & Karagiannis, S. N., Sept 2022, In: Allergy: European Journal of Allergy and Clinical Immunology. 77, 9, p. 2594-2617 24 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Atopic dermatitis and risk of autoimmune conditions: Population-based cohort study

Authors:

de Lusignan, S., Alexander, H., Broderick, C., Dennis, J., McGovern, A., Feeney, C. & Flohr, C., Sept 2022, In: Journal of Allergy and Clinical Immunology. 150, 3, p. 709-713 5 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Executive summary: The 2022 British Society for Rheumatology guideline for the treatment of psoriatic arthritis with biologic and targeted synthetic DMARDs

Authors:

Tucker, L., Allen, A., Chandler, D., Ciurtin, C., Dick, A., Foulkes, A., Gullick, N., Helliwell, P., Jadon, D., Jones, G., Kyle, S., Madhok, V., McHugh, N., Parkinson, A., Raine, T., Siebert, S., Smith, C., Tillett, W. & Coates, L. C., 30 Aug 2022, In: Rheumatology (Oxford, England). 61, 9, p. 3514-3520 7 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Vaccine hesitancy and access to psoriasis care during the COVID-19 pandemic: findings from a global patient-reported cross-sectional survey

Authors:

PsoProtect study group, Bechman, K., Cook, E. S., Dand, N., Yiu, Z. Z. N., Tsakok, T., Meynell, F., Coker, B., Vincent, A., Bachelez, H., Barbosa, I., Brown, M. A., Capon, F., Contreras, C. R., De La Cruz, C., Di Meglio, P., Gisondi, P., Jullien, D., Kelly, J. & Lambert, J. & 20 others, Lancelot, C., Langan, S. M., Mason, K. J., McAteer, H., Moorhead, L., Naldi, L., Norton, S., Puig, L., Spuls, P. I., Torres, T., Urmston, D., Vesty, A., Warren, R. B., Waweru, H., Weinman, J., Griffiths, C. M., Barker, J. N., Smith, C. H., Galloway, J. B. & Mahil, S. K., Aug 2022, In: The British journal of dermatology. 187, 2, p. 254-256 3 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Enriched circulating and tumor-resident TGF-β+ regulatory B cells in patients with melanoma promote FOXP3+ Tregs

Authors:

Harris, R. J., Willsmore, Z., Laddach, R., Crescioli, S., Chauhan, J., Cheung, A., Black, A., Geh, J. L. C., MacKenzie Ross, A. D., Healy, C., Tsoka, S., Spicer, J., Lacy, K. E. & Karagiannis, S. N., 28 Jul 2022, In: OncoImmunology. 11, 1, p. 2104426 2104426.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Immune cell-antibody interactions in health and disease

Authors:

Karagiannis, S. N. & Arnold, J. N., 22 Jul 2022, In: Clinical and Experimental Immunology. 209, 1, p. 1-3 3 p.

Research output: Contribution to journal › Article

Website | Journal

CDK Inhibition Primes for Anti-PD-L1 Treatment in Triple-Negative Breast Cancer Models

Authors:

Cheung, A., Chenoweth, A. M., Quist, J., Sow, H. S., Malaktou, C., Ferro, R., Hoffmann, R. M., Osborn, G., Sachouli, E., French, E., Marlow, R., Lacy, K. E., Papa, S., Grigoriadis, A. & Karagiannis, S. N., 11 Jul 2022, In: Cancers. 14, 14, 21 p., 3361.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Risk of severe COVID-19 outcomes associated with immune-mediated inflammatory diseases and immune-modifying therapies: a nationwide cohort study in the OpenSAFELY platform

Authors:

MacKenna, B., Kennedy, N. A., Mehrkar, A., Rowan, A., Galloway, J., Matthewman, J., Mansfield, K. E., Bechman, K., Yates, M., Brown, J., Schultze, A., Norton, S., Walker, A. J., Morton, C. E., Harrison, D., Bhaskaran, K., Rentsch, C. T., Williamson, E., Croker, R. & Bacon, S. & 28 others, Hickman, G., Ward, T., Davy, S., Green, A., Fisher, L., Hulme, W., Bates, C., Curtis, H. J., Tazare, J., Eggo, R. M., Evans, D., Inglesby, P., Cockburn, J., McDonald, H. I., Tomlinson, L. A., Mathur, R., Wong, A. Y. S., Forbes, H., Parry, J., Hester, F., Harper, S., Douglas, I. J., Smeeth, L., Lees, C. W., Evans, S. J. W., Goldacre, B., Smith, C. H. & Langan, S. M., Jul 2022, In: The Lancet Rheumatology. 4, 7, p. e490-e506

Research output: Contribution to journal › Article › peer-review

Website | Journal

Antibodies as biomarkers for cancer risk: A systematic review

Authors:

Monroy-Iglesias, M. J., Crescioli, S., Beckmann, K., Le, N., Karagiannis, S. N., Van Hemelrijck, M. & Santaolalla, A., Jul 2022, In: Clinical and Experimental Immunology. 209, 1, p. 46-63 18 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Regulatory B cell repertoire defects predispose lung cancer patients to immune-related toxicity following checkpoint blockade

Authors:

Patel, A. J., Willsmore, Z. N., Khan, N., Richter, A., Naidu, B., Drayson, M. T., Papa, S., Cope, A., Karagiannis, S. N., Perucha, E. & Middleton, G. W., 7 Jun 2022, In: Nature Communications. 13, 1, p. 3148 3148.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Differences in Clinical Features and Comorbid Burden between HLA-C∗06:02 Carrier Groups in >9,000 People with Psoriasis

Authors:

BADBIR & BSTOP Study Groups, Jun 2022, In: Journal of Investigative Dermatology. 142, 6, p. 1617-1628.e10

Research output: Contribution to journal › Article › peer-review

Website | Journal

Influence of FLG loss-of-function mutations in host–microbe interactions during atopic skin inflammation

Authors:

Oláh, P., Szlávicz, E., Kuchner, M., Nemmer, J., Zeeuwen, P., Lefèvre-Utile, A., Fyhrquist, N., Prast-Nielsen, S., Skoog, T., Serra, A., Rodríguez, E., Raap, U., Meller, S., Gyulai, R., Hupé, P., Kere, J., Levi-Schaffer, F., Tsoka, S., Alexander, H. & Nestle, F. O. & 11 others, Schröder, J. M., Weidinger, S., van den Bogaard, E., Soumelis, V., Greco, D., Barker, J., Lauerma, A., Ranki, A., Andersson, B., Alenius, H. & Homey, B., Jun 2022, In: Journal of Dermatological Science. 106, 3, p. 132-140 9 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

The importance of illness severity and multimorbidity in the association between mental health and body weight in psoriasis: Cross-sectional and longitudinal analysis

Authors:

Pavlova, N. T., Moss-Morris, R., Smith, C., Carr, E., Rayner, L. & Picariello, F., 19 Apr 2022, In: Skin Health and Disease. 2, 4, 12 p., e117.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Special Issue “Antibody Engineering for Cancer Immunotherapy”

Authors:

Special Issue "Antibody Engineering for Cancer Immunotherapy"

Crescioli, S., White, A. L. & Karagiannis, S. N., 15 Apr 2022, In: Antibodies (Basel, Switzerland). 11, 2, 29.

Research output: Contribution to journal › Editorial › peer-review

Website | Journal

Novel drug-target interactions via link prediction and network embedding

Authors:

Amiri Souri, E., Laddach, R., Karagiannis, S. N., Papageorgiou, L. G. & Tsoka, S., 4 Apr 2022, In: BMC Bioinformatics. 23, 1, 121.

Research output: Contribution to journal › Article › peer-review

Website | Journal

A multi-organ chip with matured tissue niches linked by vascular flow

Authors:

Ronaldson-Bouchard, K., Teles, D., Yeager, K., Tavakol, D. N., Zhao, Y., Chramiec, A., Tagore, S., Summers, M., Stylianos, S., Tamargo, M., Lee, B. M., Halligan, S. P., Abaci, E. H., Guo, Z., Jacków, J., Pappalardo, A., Shih, J., Soni, R. K., Sonar, S. & German, C. & 6 others, Christiano, A. M., Califano, A., Hirschi, K. K., Chen, C. S., Przekwas, A. & Vunjak-Novakovic, G., Apr 2022, In: Nature Biomedical Engineering. 6, 4, p. 351-371 21 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Two subsets of human marginal zone B cells resolved by global analysis of lymphoid tissues and blood

Authors:

Siu, J. H. Y., Pitcher, M. J., Tull, T. J., Velounias, R. L., Guesdon, W., Montorsi, L., Mahbubani, K. T., Ellis, R., Dhami, P., Todd, K., Kadolsky, U. D., Kleeman, M., D'Cruz, D. P., Saeb-Parsy, K., Bemark, M., Pettigrew, G. J. & Spencer, J., 18 Mar 2022, In: Science Immunology. 7, 69, p. eabm9060

Research output: Contribution to journal › Article › peer-review

Website | Journal

BRAF inhibitors and their immunological effects in malignant melanoma

Authors:

Adams, R., Coumbe, J. E. M., Coumbe, B. G. T., Thomas, J., Willsmore, Z., Dimitrievska, M., Yasuzawa-Parker, M., Hoyle, M., Ingar, S., Geh, J., MacKenzie Ross, A., Healy, C., Papa, S., Lacy, K. E. & Karagiannis, S. N., 23 Feb 2022, (E-pub ahead of print) In: Expert Review Of Clinical Immunology. 18, 4, p. 347-362 16 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Clinical and Translational Significance of Basophils in Patients with Cancer

Authors:

Chauhan, J., Stavraka, C., Grandits, M., Gusmao Ferreira, L. C., Josephs, D., Lacy, K. E., Spicer, J., Bax, H. & Karagiannis, S. N., 27 Jan 2022, In: Cells. 11, 3, 20 p., 438.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Targeting Cancer with CRISPR/Cas9-Based Therapy

Authors:

Balon, K., Sheriff, A., Jacków, J. & Łaczmański, Ł., 5 Jan 2022, In: International Journal of Molecular Sciences. 23, 1, 573.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Humoral and cellular immunogenicity to a second dose of COVID-19 vaccine BNT162b2 in people receiving methotrexate or targeted immunosuppression: a longitudinal cohort study

Authors:

Mahil, S. K., Bechman, K., Raharja, A., Domingo-Vila, C., Baudry, D., Brown, M. A., Cope, A. P., Dasandi, T., Graham, C., Khan, H., Lechmere, T., Malim, M. H., Meynell, F., Pollock, E., Sychowska, K., Barker, J. N., Norton, S., Galloway, J. B., Doores, K. J. & Tree, T. & 1 others, Smith, C. H., Jan 2022, In: The Lancet Rheumatology. 4, 1, p. e42-e52

Research output: Contribution to journal › Article › peer-review

Website | Journal

Engineering human skin model innervated with itch sensory neuron-like cells differentiated from induced pluripotent stem cells

Authors:

Guo, Z., Tong, C. K., Jacków, J., Doucet, Y. S., Abaci, H. E., Zeng, W., Hansen, C., Hayashi, R., DeLorenzo, D., Rami, A., Pappalardo, A., Lumpkin, E. A. & Christiano, A. M., Jan 2022, In: Bioengineering and Translational Medicine. 7, 1, e10247.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function

Authors:

MuTHER Consortium, Jan 2022, In: Nature genetics. 54, 1, p. 18-29 12 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

2021

Application of information theoretic feature selection and machine learning methods for the development of genetic risk prediction models

Authors:

BADBIR Study Group & BSTOP study group, Dec 2021, In: Scientific Reports. 11, 1, 23335.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Spectrum of mutational signatures in T-cell lymphoma reveals a key role for UV radiation in cutaneous T-cell lymphoma

Authors:

Genomics England Research Consortium, Dec 2021, In: Scientific Reports. 11, 1, 3962.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Exploring the role of immune pathways in the risk and development of depression in adolescence: research protocol of the IDEA-FLAME study

Authors:

Mondelli, V., Cattaneo, A., Nikkheslat, N., Souza, L., Walsh, A., Zajkowska, Z., Zonca, V., Marizzoni, M., Fisher, H., Kohrt, B. A., Kieling, C. & Di Meglio, P., 1 Dec 2021, In: Brain, Behavior, & Immunity - Health. 18

Research output: Contribution to journal › Article › peer-review

Website | Journal

Macrophages in ovarian cancer and their interactions with monoclonal antibody therapies

Authors:

Osborn, G., Stavraka, C., Adams, R., Sayasneh, A., Ghosh, S., Montes, A., Lacy, K. E., Kristeleit, R., Spicer, J., Josephs, D., Arnold, J. & Karagiannis, S. N., 22 Nov 2021, (E-pub ahead of print) In: Clin Exp Immunol.

Research output: Contribution to journal › Article › peer-review

Website | Journal

DIFFERENCES IN CLINICAL FEATURES AND COMORBID BURDEN BETWEEN HLA-C*06:02 CARRIER GROUPS IN MORE THAN 9,000 PEOPLE WITH PSORIASIS

Authors:

Douroudis, K., Ramessur, R., Biscaia De Andrade Barbosa, I., Baudry, D., Duckworth, M., Angit, C., Capon, F., Chung, R., Curtis, C., DiMeglio, P., Goudling, J., Griffiths, C., Lee, S., Mahil, S., Parslew, R., Reynolds, N., Shipman, A., warren, R., Yiu, Z. & Simpson, M. & 3 others, Barker, J., Dand, N. & Smith, C., 21 Nov 2021, In: Journal of Investigative Dermatology.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Glycoengineering of Therapeutic Antibodies with Small Molecule Inhibitors

Authors:

Li, S., McCraw, A. J., Gardner, R. A., Spencer, D. I. R., Karagiannis, S. N. & Wagner, G. K., 4 Nov 2021, In: Antibodies (Basel, Switzerland). 10, 4, 20 p., 44.

Research output: Contribution to journal › Article › peer-review

Website | Journal

The BIOMarkers in Atopic Dermatitis and Psoriasis (BIOMAP) glossary: developing a lingua franca to facilitate data harmonization and cross-cohort analyses

Authors:

the BIOMAP consortium, Broderick, C., Christian, N., Apfelbacher, C., Bosma, A. L., Dand, N., Ghosh, S., Hangel, N., Hübenthal, M., Middelkamp-Hup, M. A., Min, J. L., Musters, A. H., Paternoster, L., Rodríguez, E., Satagopam, V., Scordis, P., Spuls, P. I., Szymczak, S., Weidinger, S. & Smith, C. H. & 1 others, Flohr, C., Nov 2021, In: British Journal of Dermatology. 185, 5, p. 1066-1069 4 p.

Research output: Contribution to journal › Letter › peer-review

Website | Journal

Patient preferences for stratified medicine in psoriasis: a discrete choice experiment

Authors:

the PSORT Consortium, Nov 2021, In: British Journal of Dermatology. 185, 5, p. 978-987 10 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Chemokine Pathways in Cutaneous Melanoma: Their Modulation by Cancer and Exploitation by the Clinician

Authors:

Adams, R., Moser, B., Karagiannis, S. N. & Lacy, K. E., 1 Nov 2021, In: Cancers. 13, 22, 5625.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Ancestral patterns of recessive dystrophic epidermolysis bullosa mutations in Hispanic populations suggest sephardic ancestry

Authors:

Warshauer, E. M., Brown, A., Fuentes, I., Shortt, J., Gignoux, C., Montinaro, F., Metspalu, M., Youssefian, L., Vahidnezhad, H., Jacków, J., Christiano, A. M., Uitto, J., Fajardo-Ramírez, Ó. R., Salas-Alanis, J. C., McGrath, J. A., Consuegra, L., Rivera, C., Maier, P. A., Runfeldt, G. & Behar, D. M. & 8 others, Skorecki, K., Sprecher, E., Palisson, F., Norris, D. A., Bruckner, A. L., Kogut, I., Bilousova, G. & Roop, D. R., Nov 2021, In: American Journal of Medical Genetics, Part A. 185, 11, p. 3390-3400 11 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Anakinra for palmoplantar pustulosis: results from a randomized, double-blind, multicentre, two-staged, adaptive placebo-controlled trial (APRICOT)

Authors:

the APRICOT Study Group, 12 Oct 2021, (E-pub ahead of print) In: British Journal of Dermatology.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Is there a role for physical activity when treating patients with cancer with immune checkpoint inhibitors? Protocol for a scoping review

Authors:

Chen, M., Raj, R., Fox, L., Moss, C. L., George, G., Karagiannis, S. N., Enting, D., Joseph, M., Peat, N., Russell, B. & Van Hemelrijck, M., 8 Oct 2021, In: BMJ Open. 11, 10, p. e046052 e046052.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Going through a rough patch: oral adverse effects of secukinumab

Authors:

Yogarajah, S., Mahendran, K., Barker, J., Setterfield, J. & Carey, B., 8 Oct 2021, (E-pub ahead of print) In: Oral Surgery.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Describing the burden of the COVID-19 pandemic in people with psoriasis: findings from a global cross-sectional study

Authors:

PsoProtect study group, Oct 2021, In: Journal of the European Academy of Dermatology and Venereology : JEADV. 35, 10, p. e636-e640

Research output: Contribution to journal › Article › peer-review

Website | Journal

Association between Tumor Necrosis Factor Inhibitors and the Risk of Hospitalization or Death among Patients with Immune-Mediated Inflammatory Disease and COVID-19

Authors:

Izadi, Z., Brenner, E. J., Mahil, S. K., Dand, N., Yiu, Z. Z. N., Yates, M., Ungaro, R. C., Zhang, X., Agrawal, M., Colombel, J. F., Gianfrancesco, M. A., Hyrich, K. L., Strangfeld, A., Carmona, L., Mateus, E. F., Lawson-Tovey, S., Klingberg, E., Cuomo, G., Caprioli, M. & Cruz-Machado, A. R. & 45 others, Mazeda Pereira, A. C., Hasseli, R., Pfeil, A., Lorenz, H. M., Hoyer, B. F., Trupin, L., Rush, S., Katz, P., Schmajuk, G., Jacobsohn, L., Seet, A. M., Al Emadi, S., Wise, L., Gilbert, E. L., Duarte-García, A., Valenzuela-Almada, M. O., Isnardi, C. A., Quintana, R., Soriano, E. R., Hsu, T. Y. T., D'Silva, K. M., Sparks, J. A., Patel, N. J., Xavier, R. M., Marques, C. D. L., Kakehasi, A. M., Flipo, R. M., Claudepierre, P., Cantagrel, A., Goupille, P., Wallace, Z. S., Bhana, S., Costello, W., Grainger, R., Hausmann, J. S., Liew, J. W., Sirotich, E., Sufka, P., Robinson, P. C., Machado, P. M., Griffiths, C. E. M., Barker, J. N., Smith, C. H., Yazdany, J. & Kappelman, M. D., 1 Oct 2021, In: JAMA Network open. 4, 10, p. e2129639

Research output: Contribution to journal › Article › peer-review

Website | Journal

Dermatology COVID-19 Registries: Updates and Future Directions

Authors:

Freeman, E. E., Chamberlin, G. C., McMahon, D. E., Hruza, G. J., Wall, D., Meah, N., Sinclair, R., Balogh, E. A., Feldman, S. R., Lowes, M. A., Marzano, A. V., Naik, H. B., Castelo-Soccio, L., Lara-Corrales, I., Cordoro, K. M., Mahil, S. K., Griffiths, C. E. M., Smith, C. H., Irvine, A. D. & Spuls, P. I. & 2 others, Flohr, C. & French, L. E., 1 Oct 2021, In: Dermatologic clinics. 39, 4, p. 575-585 11 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

The power and potential of BIOMAP to elucidate host-microbiome interplay in skin inflammatory diseases

Authors:

Alenius, H., Sinkko, H., Moitinho-Silva, L., Rodriguez, E., Broderick, C., Alexander, H., Reiger, M., Hjelmsø, M. H., Fyhrquist, N., Olah, P., Bryce, P., Smith, C., Koning, F., Eyerich, K., Greco, D., van den Bogaard, E. H., Neumann, A. U., Traidl-Hoffmann, C., Homey, B. & Flohr, C. & 3 others, Bønnelykke, K., Stokholm, J. & Weidinger, S., Oct 2021, In: Experimental Dermatology. 30, 10, p. 1517-1531 15 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Defining trajectories of response in patients with psoriasis treated with biologic therapies

Authors:

the BADBIR Study Group & the PSORT Consortium, Oct 2021, In: British Journal of Dermatology. 185, 4, p. 825-835 11 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

There is no proven association between sensitization to benzyl salicylate and frontal fibrosing alopecia

Authors:

Rayinda, T., McSweeney, S. M., McFadden, J. P., White, I. R., McGrath, J. A. & Tziotzios, C., Oct 2021, In: Contact Dermatitis. 85, 4, p. 483-484 2 p.

Research output: Contribution to journal › Letter › peer-review

Website | Journal

Health Economic Assessment of Optimal Biological Treatment for Moderate-to-Severe Psoriasis

Authors:

Barker, J., Baker, H., Nadeem, A., Gu, D. H. & Girolomoni, G., 1 Oct 2021, In: CLINICAL DRUG INVESTIGATION. 41, 11, p. 1011-1020 10 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Insights from IgE immune surveillance in allergy and cancer for anti-tumour IgE treatments

Authors:

McCraw, A., Chauhan, J., Stavraka, C., Osborn, G., Grandits, M., Lopez-Abente Muroz, J., Josephs, D., Spicer, J., Wagner, G. K., Karagiannis, S. N., Chenoweth, A. & Crescioli, S., 4 Sept 2021, In: Cancers. 13, 17, 17 p., 4460.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Cancer Grade Model: a multi-gene machine learning-based risk classification for improving prognosis in breast cancer

Authors:

Amiri Souri, E., Chenoweth, A., Cheung, A., Karagiannis, S. N. & Tsoka, S., 31 Aug 2021, In: British Journal of Cancer; Nature Research. 125, 5, p. 748-758 11 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

B lymphocytes accumulate and proliferate in human skin at sites of cutaneous antigen challenge

Authors:

Egbuniwe, I. U., Harris, R. J., Nakamura, M., Nestle, F. O., Akbar, A. N., Karagiannis, S. N. & Lacy, K. E., 26 Aug 2021, (E-pub ahead of print) In: Journal of Investigative Dermatology.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Tumor-Infiltrating B Lymphocyte Profiling Identifies IgG-Biased, Clonally Expanded Prognostic Phenotypes In Triple-Negative Breast Cancer

Authors:

Harris, R. J., Cheung, A., Ng, J. C. F., Laddach, R., Chenoweth, A. M., Crescioli, S., Fittall, M., Dominguez-Rodriguez, D., Roberts, J., Levi, D., Liu, F., Alberts, E., Quist, J., Santaolalla, A., Pinder, S. E., Gillett, C., Hammar, N., Irshad, S., van Hemelrijck, M. & Dunn-Walters, D. K. & 7 others, Fraternali, F., Spicer, J. F., Lacy, K. E., Tsoka, S., Grigoriadis, A., Tutt, A. N. J. & Karagiannis, S. N., 15 Aug 2021, In: Cancer Research. 81, 16, p. 4290-4304 15 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Guardians of the barrier: Microbiota engage AHR in keratinocytes to mantain skin homeostasis

Authors:

Alwan, W. & Di Meglio, P., 11 Aug 2021, In: Cell Host & Microbe. 29, 8, p. 1213-1216 4 p.

Research output: Contribution to journal › Comment/debate › peer-review

Website | Journal

Enhanced NF-κB signaling in type-2 dendritic cells at baseline predicts non-response to adalimumab in psoriasis

Authors:

Andres Ejarque, R., Ale, H. B. A., Grys, K., Tosi, I., Solanky, S., Ainali, C., Catak, Z., Sreeneebus, H., Saklatvala, J., Dand, N., de Rinaldis, E., Chapman, A., Nestle, F., Barnes, M. R., Richard, W., Reynolds, N. J., Griffiths, C., Barker, J., Smith, C. & Di Meglio, P. & 1 others, COnsortium, P., 6 Aug 2021, In: Nature Communications. 12, 1, p. 4741 1 p., 4741.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Risks of basal cell and squamous cell carcinoma in psoriasis patients after treatment with biologic vs non-biologic systemic therapies

Authors:

the BADBIR Study Group, Aug 2021, In: Journal of the European Academy of Dermatology and Venereology. 35, 8, p. e496-e498

Research output: Contribution to journal › Letter › peer-review

Website | Journal

Characteristics and skin cancer risk of psoriasis patients with a history of skin cancer in BADBIR

Authors:

the BADBIR Study Group, Aug 2021, In: Journal of the European Academy of Dermatology and Venereology. 35, 8, p. e498-e501

Research output: Contribution to journal › Letter › peer-review

Website | Journal

Meeting Report: Psoriasis Stratification to Optimize Relevant Therapy Showcase

Authors:

PSORT consortium, Aug 2021, In: Journal of Investigative Dermatology. 141, 8, p. 1872-1878 7 p.

Research output: Contribution to journal › Comment/debate › peer-review

Website | Journal

Castration-mediated IL-8 promotes myeloid infiltration and prostate cancer progression

Authors:

Lopez-Bujanda, Z. A., Haffner, M. C., Chaimowitz, M. G., Chowdhury, N., Venturini, N. J., Patel, R. A., Obradovic, A., Hansen, C. S., Jacków, J., Maynard, J. P., Sfanos, K. S., Abate-Shen, C., Bieberich, C. J., Hurley, P. J., Selby, M. J., Korman, A. J., Christiano, A. M., De Marzo, A. M. & Drake, C. G., Aug 2021, In: Nature Cancer. 2, 8, p. 803-818 16 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Antiviral antibody responses to systemic administration of an oncolytic RNA virus: the impact of standard concomitant anticancer chemotherapies

Authors:

Roulstone, V., Mansfield, D., Harris, R., Twigger, K., White, C., de Bono, J. S., Spicer, J., Karagiannis, S. N., Vile, R., Pandha, H., Melcher, A. & Harrington, K., 22 Jul 2021, In: Journal for ImmunoTherapy of Cancer. 9, 7, e002673.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Translational aspects of biologicals: monoclonal antibodies and antibody-drug conjugates as examples

Authors:

Karagiannis, S. N., Hoffmann, M., Nakamura, M., Crescioli, S., Bax, H. J., Chenoweth, A., Cheung, A., Tsoka, S., Spicer, J., Lacy, K. E. & Thurston, D., 15 Jul 2021, Principles of Translational Science in Medicine: From Bench to Bedside, Third Edition. Wehling, M. (ed.). 3rd ed. Academic Press, p. 329-350 22 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Website | Journal

Risk mitigating behaviours in people with inflammatory skin and joint disease during the COVID-19 pandemic differ by treatment type: a cross-sectional patient survey

Authors:

Mahil, S. K., Yates, M., Langan, S. M., Yiu, Z. Z. N., Tsakok, T., Dand, N., Mason, K. J., Mcateer, H., Meynell, F., Coker, B., Vincent, A., Urmston, D., Vesty, A., Kelly, J., Lancelot, C., Moorhead, L., Bachelez, H., Bruce, I. N., Capon, F. & Contreras, C. R. & 23 others, Cope, A. P., De la cruz, C., Di Meglio, P., Gisondi, P., Hyrich, K., Jullien, D., Lambert, J., Marzo‐ortega, H., Mcinnes, I., Naldi, L., Norton, S., Puig, L., Sengupta, R., Spuls, P., Torres, T., Warren, R. B., Waweru, H., Weinman, J., Griffiths, C. E. M., Barker, J. N., Brown, M. A., Galloway, J. B. & Smith, C. H., 1 Jul 2021, In: British Journal of Dermatology. 185, 1, p. 80-90

Research output: Contribution to journal › Article › peer-review

Website | Journal

Psychosocial aspects of obesity in adults with psoriasis: A systematic review

Authors:

Pavlova, N. T., Kioskli, K., Smith, C., Picariello, F., Rayner, L. & Moss-Morris, R., Jun 2021, In: Skin Health and Disease. 1, 2, e33.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Learning from disease registries during a pandemic: Moving toward an international federation of patient registries

Authors:

Wall, D., Alhusayen, R., Arents, B., Apfelbacher, C., Balogh, E. A., Bokhari, L., Bloem, M., Bosma, A. L., Burton, T., Castelo-Soccio, L., Fagan, N., Feldman, S. R., Fletcher, G., Flohr, C., Freeman, E., French, L. E., Griffiths, C. E. M., Hruza, G. J., Ingram, J. R. & Kappelman, M. D. & 14 others, Lara-Corrales, I., Lim, H. W., Meah, N., McMahon, D. E., Mahil, S. K., McNicoll, I., Musters, A., Naik, H. B., Sinclair, R., Smith, C. H., Spuls, P., Tobin, D. J., York, K. & Irvine, A. D., 1 May 2021, In: Clinics in Dermatology. 39, 3, p. 467-478 12 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Human marginal zone B cell development from early T2 progenitors

Authors:

Spencer, J., Tull, T., Pitcher, M., Guesdon, W., Siu, J. H., Lebraro-Fernandez, C., Zhao, Y., Petrov, N., Heck, S., Ellis, R., Dhami, P., kadolsky, U., Kleeman, M., Kamra, Y., Fear, D., John, S., Jassem, W., Groves, R., Sanderson, J. D. & Robson, M. & 2 others, D’Cruz, D. & Bemark, M., 5 Apr 2021, In: Journal of Experimental Medicine. 218, 4, e20202001.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Real-world effectiveness and tolerability of dupilumab in adult atopic dermatitis: a single-centre, prospective 1-year observational cohort study of the first 100 patients treated

Authors:

Sears, A. V., Woolf, R. T., Gribaleva, E., Abdelrahman, W., Robbie, S., Menon, B., Kirkham, B., Smith, C. H. & Pink, A. E., Apr 2021, In: British Journal of Dermatology. 184, 4, p. 755-757 3 p.

Research output: Contribution to journal › Letter › peer-review

Website | Journal

Association of Patient Mental Health Status With the Level of Agreement Between Patient and Physician Ratings of Psoriasis Severity

Authors:

Carr, E., Mahil, S. K., Brailean, A., Dasandi, T., Pink, A. E., Barker, J., Rayner, L., Turner, M., Goldsmith, K. & Smith, C. H., Apr 2021, In: JAMA dermatology. 157, 4, p. 413-420 8 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Combined anti-PD-1 and anti-CTLA-4 checkpoint blockade: treatment of melanoma and immune mechanisms of action

Authors:

Willsmore, Z. N., Coumbe, B. G. T., Crescioli, S., Reci, S., Gupta, A., Harris, R. J., Chenoweth, A., Chauhan, J., Bax, H. J., McCraw, A., Cheung, A., Osborn, G., Hoffmann, R. M., Nakamura, M., Laddach, R., Geh, J. L. C., Ross, A. M., Healy, C., Tsoka, S. & Spicer, J. F. & 4 others, Josephs, D. H., Papa, S., Lacy, K. E. & Karagiannis, S. N., Mar 2021, In: European Journal of Immunology. 51, 3, p. 544-556 13 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

B Cells in Patients With Melanoma: Implications for Treatment With Checkpoint Inhibitor Antibodies

Authors:

Willsmore, Z. N., Harris, R. J., Crescioli, S., Hussein, K., Kakkassery, H., Thapa, D., Cheung, A., Chauhan, J., Bax, H. J., Chenoweth, A., Laddach, R., Osborn, G., McCraw, A., Hoffmann, R. M., Nakamura, M., Geh, J. L., MacKenzie-Ross, A., Healy, C., Tsoka, S. & Spicer, J. F. & 4 others, Papa, S., Barber, L., Lacy, K. E. & Karagiannis, S. N., 25 Jan 2021, In: Frontiers in Immunology. 11, 622442.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Reprogramming and differentiation of cutaneous squamous cell carcinoma cells in recessive dystrophic epidermolysis bullosa

Authors:

Rami, A., Łaczmański, Ł., Jacków-Nowicka, J. & Jacków, J., 1 Jan 2021, In: International Journal of Molecular Sciences. 22, 1, p. 1-14 14 p., 245.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Factors associated with adverse COVID-19 outcomes in patients with psoriasis – insights from a global registry-based study

Authors:

Factors associated with adverse COVID-19 outcomes in patients with psoriasis - insights from a global registry-based study

PsoProtect study group, Jan 2021, In: Journal of Allergy and Clinical Immunology. 147, 1, p. 60-71 12 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Quantitative Evaluation of Biologic Therapy Options for Psoriasis: A Systematic Review and Network Meta-Analysis–Correction

Authors:

Smith, C. H., Mahil, S. K., Yiu, Z. Z. N., Bale, T., Burden, A. D., Coates, L. C., McGuire, A., Murphy, R., Owen, C. M., Parslew, R., Uthman, O. A., Woolf, R. T., Manounah, L., Ezejimofor, M. C., Exton, L. S. & Mohd Mustapa, M. F., Jan 2021, In: Journal of Investigative Dermatology. 141, 1, p. 177-181 5 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

2020

CYP1A1 enzymatic activity influences skin inflammation via regulation of the AHR pathway

Authors:

Kyoreva, M., Li, Y., Hoosenally, M., Hardman-Smart, J., Morrison, K., Tosi, I., Tolaini, M., Barinaga, G., Stockinger, B., Mrowietz, U., Nestle, F., Smith, C., Barker, J. & Di Meglio, P., 29 Dec 2020, (E-pub ahead of print) In: Journal of Investigative Dermatology.

Research output: Contribution to journal › Article › peer-review

Website | Journal

IgE antibodies against cancer: efficacy and safety

Authors:

Chauhan, J., McCraw, A. J., Nakamura, M., Osborn, G., Sow, H. S., Stavraka, C., Josephs, D., Spicer, J., Karagiannis, S. N. & Bax, H., 1 Dec 2020, In: Antibodies (Basel, Switzerland). 9, 4, p. 1-27 27 p., 55.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

The British Association of Dermatologists Biologics and Immunomodulators Register: a centenary celebration of research collaboration in British dermatology

Authors:

the BADBIR Study Group, Dec 2020, In: British Journal of Dermatology. 183, 6, p. 981-983 3 p.

Research output: Contribution to journal › Editorial › peer-review

Website | Journal

In chronic plaque psoriasis, roflumilast cream safely increased likelihood of clear or almost clear state at 6 weeks

Authors:

Mahil, S. K. & Smith, C. H., 17 Nov 2020, In: Annals of internal medicine. 173, 10, p. JC55

Research output: Contribution to journal › Article › peer-review

Website | Journal

IgE Activates Monocytes from Cancer Patients to Acquire a Pro-Inflammatory Phenotype

Authors:

Nakamura, M., Souri, E. A., Osborn, G., Laddach, R., Chauhan, J., Stavraka, C., Lombardi, S., Black, A., Khiabany, A., Khair, D. O., Figini, M., Winship, A., Ghosh, S., Montes, A., Spicer, J. F., Bax, H. J., Josephs, D. H., Lacy, K. E., Tsoka, S. & Karagiannis, S. N., 15 Nov 2020, In: Cancers. 12, 11, p. 1-19 19 p., 3376.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Clinical Impact of Antibodies against Ustekinumab in Psoriasis: An Observational, Cross-Sectional, Multicenter Study

Authors:

BADBIR, BSTOP Study Groups & PSORT consortium, Nov 2020, In: Journal of Investigative Dermatology. 140, 11, p. 2129-2137 9 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Association of Clinical and Demographic Factors With the Severity of Palmoplantar Pustulosis: Findings from the APRICOT, PLUM and ERASPEN consortia

Authors:

ERASPEN consortium and the APRICOT and PLUM study team, Nov 2020, In: JAMA dermatology. 156, 11, p. 1216-1222 7 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Microbial and transcriptional differences elucidate atopic dermatitis heterogeneity across skin sites

Authors:

Ottman, N., Barrientos-Somarribas, M., Fyhrquist, N., Alexander, H., Wisgrill, L., Olah, P., Tsoka, S., Greco, D., Levi-Schaffer, F., Soumelis, V., Schröder, J. M., Kere, J., Nestle, F. O., Barker, J., Ranki, A., Lauerma, A., Homey, B., Andersson, B. & Alenius, H., 14 Oct 2020, (E-pub ahead of print) In: Allergy: European Journal of Allergy and Clinical Immunology. 76, 4, 15 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

ESDR 2010–2020: Journey toward Translational and Systems Dermatology

Authors:

Schmuth, M., Biedermann, T., Picardo, M., Florestan, T. & Barker, J., Sept 2020, In: Journal of Investigative Dermatology. 140, 9, p. S167-S170

Research output: Contribution to journal › Comment/debate › peer-review

Website | Journal

International collaboration and rapid harmonization across dermatologic COVID-19 registries

Authors:

Freeman, E. E., McMahon, D. E., Hruza, G. J., Irvine, A. D., Spuls, P. I., Smith, C. H., Mahil, S. K., Castelo-Soccio, L., Cordoro, K. M., Lara-Corrales, I., Naik, H. B., Alhusayen, R., Ingram, J. R., Feldman, S. R., Balogh, E. A., Kappelman, M. D., Wall, D., Meah, N., Sinclair, R. & Beylot-Barry, M. & 5 others, Fitzgerald, M., French, L. E., Lim, H. W., Griffiths, C. E. M. & Flohr, C., Sept 2020, In: Journal of the American Academy of Dermatology. 83, 3, p. e261-e266

Research output: Contribution to journal › Letter › peer-review

Website | Journal

Global reporting of cases of COVID-19 in psoriasis and atopic dermatitis: an opportunity to inform care during a pandemic

Authors:

The Secure-AD, PsoPROTECT study groups, 1 Aug 2020, In: British Journal of Dermatology. 183, 2, p. 404-406 3 p.

Research output: Contribution to journal › Letter › peer-review

Website | Journal

Clinical characteristics including cardiovascular and metabolic risk factors in adolescents with psoriasis

Authors:

Blegvad, C., Nybo Andersen, A. M., Groot, J., Zachariae, C., Barker, J. & Skov, L., 1 Jul 2020, In: Journal of The European Academy of Dermatology and Venereology. 34, 7, p. 1516-1523 8 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Harnessing the immune system via FcγR function in immune therapy: a pathway to next-gen mAbs

Authors:

Chenoweth, A. M., Wines, B. D., Anania, J. C. & Mark Hogarth, P., 1 Apr 2020, In: Immunology and Cell Biology. 98, 4, p. 287-304 18 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

IL-36 Promotes Systemic IFN-I Responses in Severe Forms of Psoriasis

Authors:

Catapano, M., Vergnano, M., Romano, M., Mahil, S. K., Choon, S.-E., Burden, A. D., Young, H. S., Carr, I. M., Lachmann, H. J., Lombardi, G., Smith, C. H., Ciccarelli, F. D., Barker, J. N. & Capon, F., 1 Apr 2020, In: Journal of Investigative Dermatology. 140, 4, p. 816-826.e3

Research output: Contribution to journal › Article › peer-review

Website | Journal

Recapitulating T cell infiltration in 3D psoriatic skin models for patient-specific drug testing

Authors:

Shin, J. U., Abaci, H. E., Herron, L., Guo, Z., Sallee, B., Pappalardo, A., Jackow, J., Wang, E. H. C., Doucet, Y. & Christiano, A. M., 5 Mar 2020, In: Scientific Reports. 10, 1, 4123.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Using Real-World Data to Guide Ustekinumab Dosing Strategies for Psoriasis: A Prospective Pharmacokinetic-Pharmacodynamic Study

Authors:

BADBIR Study Group, the BSTOP Study Group, the PSORT Consortium, Pan, S., Tsakok, T., Dand, N., Lonsdale, D. O., Loeff, F. C., Bloem, K., de Vries, A., Baudry, D., Duckworth, M., Mahil, S., Pushpa-Rajah, A., Russell, A., Alsharqi, A., Becher, G., Murphy, R., Wahie, S., Wright, A., Griffiths, C. E. M. & Reynolds, N. J. & 6 others, Barker, J., Warren, R. B., David Burden, A., Rispens, T., Standing, J. F. & Smith, C. H., 1 Mar 2020, In: Clinical and Translational Science. 13, 2, p. 400-409 10 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

T-cell phenotyping uncovers systemic features of atopic dermatitis and psoriasis

Authors:

Farrera, C., Melchiotti, R., Petrov, N., Wei Weng Teng, K., Wong, M. T., Loh, C. Y., Villanova, F., Tosi, I., Chen, J., Grys, K., Sreeneebus, H., Chapman, A., Perera, G. K., Heck, S., Gracio, F., de Rinaldis, E., Barker, J. N., Smith, C. H., Nestle, F. O. & Newell, E. W. & 1 others, Di Meglio, P., 1 Mar 2020, In: Journal of Allergy and Clinical Immunology. 145, 3, p. 1021-1025.e15

Research output: Contribution to journal › Article › peer-review

Website | Journal

A randomised placebo controlled trial of anakinra for treating pustular psoriasis: Statistical analysis plan for stage two of the APRICOT trial

Authors:

Cro, S., Patel, P., Barker, J., Burden, D. A., Griffiths, C. E. M., Lachmann, H. J., Reynolds, N. J., Warren, R. B., Capon, F., Smith, C. & Cornelius, V., 10 Feb 2020, In: Trials. 21, 1, 158.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Frequent and Persistent PLCG1 Mutations in Sézary Cells Directly Enhance PLCγ1 Activity and Stimulate NFκB, AP-1, and NFAT Signaling

Authors:

Patel, V. M., Flanagan, C. E., Martins, M., Jones, C. L., Butler, R. M., Woollard, W. J., Bakr, F. S., Yoxall, A., Begum, N., Katan, M., Whittaker, S. J. & Mitchell, T. J., 1 Feb 2020, In: Journal of Investigative Dermatology. 140, 2, p. 380-389.e4

Research output: Contribution to journal › Article › peer-review

Website | Journal

Association between preadmission frailty and care level at discharge in older adults undergoing emergency laparotomy

Authors:

on behalf of the ELF Study Group, 1 Feb 2020, In: British Journal of Surgery. 107, 3, p. 218-226 9 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Psoriasis and Genetics

Authors:

Dand, N., Mahil, S. K., Capon, F., Smith, C. H., Simpson, M. A. & Barker, J. N., 30 Jan 2020, In: Acta Dermato-Venereologica. 100, 100-year theme: Psoriasis, p. 54-64 11 p., adv00030.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Immunogenicity of biologic therapies in psoriasis: Myths, facts and a suggested approach

Authors:

Tsakok, T., Rispens, T., Spuls, P., Nast, A., Smith, C. & Reich, K., 2020, (Accepted/In press) In: Journal of the European Academy of Dermatology and Venereology.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Targeting the Jak/Signal Transducer and Activator Of Transcription 3 Pathway with Ruxolitinib in a Mouse Model of Recessive Dystrophic Epidermolysis Bullosa–Squamous Cell Carcinoma

Authors:

Jacków, J., Rami, A., Hayashi, R., Hansen, C., Guo, Z., DeLorenzo, D., Pappalardo, A., Alvarez Cespedes, D., Kim, A. L., Perez-Lorenzo, R., Owens, D. M. & Christiano, A. M., 2020, (Accepted/In press) In: Journal of Investigative Dermatology.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Patterns and trends in eczema management in UK primary care (2009–2018): A population-based cohort study

Authors:

de Lusignan, S., Alexander, H., Broderick, C., Dennis, J., McGovern, A., Feeney, C. & Flohr, C., 2020, (Accepted/In press) In: Clinical and Experimental Allergy.

Research output: Contribution to journal › Article › peer-review

Website | Journal

The epidemiology of eczema in children and adults in England: A population-based study using primary care data

Authors:

de Lusignan, S., Alexander, H., Broderick, C., Dennis, J., McGovern, A., Feeney, C. & Flohr, C., 2020, (Accepted/In press) In: Clinical and Experimental Allergy.

Research output: Contribution to journal › Article › peer-review

Website | Journal

2019

CRISPR/Cas9-based targeted genome editing for correction of recessive dystrophic epidermolysis bullosa using iPS cells

Authors:

Jacków, J., Guo, Z., Hansen, C., Abaci, H. E., Doucet, Y. S., Shin, J. U., Hayashi, R., DeLorenzo, D., Kabata, Y., Shinkuma, S., Salas-Alanis, J. C. & Christiano, A. M., 26 Dec 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 52, p. 26846-26852 7 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Developing an online patient education resource for topical therapy: a pilot study

Authors:

Tull, T. J., Jackson, K., Smith, C. H. & Pink, A. E., 6 Nov 2019, (E-pub ahead of print) In: British Journal of Dermatology. 182, 2, p. 508-509

Research output: Contribution to journal › Letter › peer-review

Website | Journal

Sneddon Syndrome associated with two novel ADA2 gene mutations

Authors:

Tull, T. J., Martin, B., Spencer, J. M., Sangle, S., Chua, S., McGrath, J. A., D'Cruz, D. & McGibbon, D. H., 29 Oct 2019, (Accepted/In press) In: Rheumatology.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Microbe-host interplay in atopic dermatitis and psoriasis

Authors:

Fyhrquist, N., Muirhead, G. S., Prast-Nielsen, S., Jeanmougin, M., Olah, P., Skoog, T., Jules-Clement, G., Feld, M., Barrientos-Somarribas, M., Sinkko, H., van den Bogaard, E. H., Zeeuwen, P. L. J. M., Rikken, G., Schalkwijk, J., Niehues, N., Däubener, W., Eller, S. K., Alexander, H., Pennino, D. & Suomela, S. & 27 others, Tessas, I., Lybeck, E., Baran, A. M., Darban, H., Roopesh Singh, G., Gerstel, U., Jahn, K., Karisola, P., Yan, L., Hansmann, B., Katayama, S., Meller, S., Bylesjö, M., Hupé, P., Levi-Schaffer, F., Greco, D., Ranki, A., Schröder, J. M., Barker, J. N. W. N., Kere, J., Tsoka, S., Lauerma, A., Soumelis, V., Nestle, F. O., Homey, B., Andersson, B. & Alenius, H., 16 Oct 2019, (E-pub ahead of print) In: Nature Communications. 10, 1, 4703.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Psoriasis biologics: a new era of choice

Authors:

Mahil, S. K. & Smith, C. H., 7 Sept 2019, In: Lancet. 394, 10201, p. 807-808 2 p.

Research output: Contribution to journal › Comment/debate › peer-review

Website | Journal

Contribution of STAT3 and RAD23B in Primary Sézary Cells to Histone Deacetylase Inhibitor FK228 Resistance

Authors:

Butler, R. M., Mckenzie, R. C., Jones, C. L., Flanagan, C. E., Woollard, W. J., Demontis, M., Ferreira, S., Tosi, I., John, S., Whittaker, S. J. & Mitchell, T. J., 1 Sept 2019, In: Journal of Investigative Dermatology. 139, 9, p. 1975-1984.e2

Research output: Contribution to journal › Article › peer-review

Website | Journal

Immune mediator expression signatures are associated with improved outcome in ovarian carcinoma

Authors:

Nakamura, M., Bax, H. J., Scotto, D., Amiri Souri, E., Sollie, S., Harris, R. J., Hammar, N., Walldius, G., Winship, A., Ghosh, S., Montes, A., Spicer, J. F., Van Hemelrijck, M., Josephs, D. H., Lacy, K. E., Tsoka, S. & Karagiannis, S. N., 3 Jun 2019, In: OncoImmunology. 8, 6, e1593811 .

Research output: Contribution to journal › Article › peer-review

Website | Journal

Combining Immune Checkpoint Inhibitors: Established and Emerging Targets and Strategies to Improve Outcomes in Melanoma

Authors:

Khair, D. O., Bax, H. J., Mele, S., Crescioli, S., Pellizzari, G., Khiabany, A., Nakamura, M., Harris, R. J., French, E., Hoffmann, R. M., Williams, I. P., Cheung, K. K. A., Thair, B., Beales, C. T., Touizer, E., Signell, A. W., Tasnova, N. L., Spicer, J. F., Josephs, D. H. & Geh, J. L. C. & 5 others, MacKenzie Ross, A., Healy, C., Papa, S. E., Lacy, K. E. & Karagiannis, S. N., 19 Mar 2019, In: Frontiers in Immunology. MAR, 453.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Reduced CD27-IgD- B cells in blood and raised CD27-IgD- B cells in gut-associated lymphoid tissue in inflammatory bowel disease.

Authors:

Pararasa, C., Zhang, N., Tull, T. J., Chong, M. H., Siu, J. H., Guesdon, W. W. J., Chavele, K.-M., Sanderson, J., Langmead, L., Kok, K., Spencer, J. M. & vossenkamper, A., 5 Mar 2019, In: Frontiers in Immunology. 10, 361.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Association of Serum Ustekinumab Levels with Clinical Response in Psoriasis

Authors:

Tsakok, T., Wilson, N., Dand, N., Loeff, F. C., Bloem, K., Baudry, D., Duckworth, M., Pan, S., Pushpa-Rajah, A., Standing, J. F., De Vries, A., Alsharqi, A., Becher, G., Murphy, R., Wahie, S., Wright, A., Griffiths, C. E. M., Reynolds, N. J., Barker, J. & Warren, R. B. & 4 others, Burden, A. D., Rispens, T., Stocken, D. & Smith, C., 2019, In: JAMA dermatology. 155, 11, p. 1235-1243 9 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Defining the therapeutic range for adalimumab and predicting response in psoriasis: a multicenter prospective observational cohort study

Authors:

Wilkinson, N., Tsakok, T., Dand, N., Bloem, K., Duckworth, M., Baudry, D., Pushpa-Rajah, A., Griffiths, C. E., Reynolds, N. J., Barker, J., Warren, R. B., Burden, A. D., Rispens, T., Stocken, D. & Smith, C., 1 Jan 2019, In: Journal of Investigative Dermatology. 139, 1, p. 115-123 9 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Secukinumab for patients failing previous tumour necrosis factor-α inhibitor therapy: results of a randomized open-label study (SIGNATURE)

Authors:

Warren, R. B., Barker, J. N. W. B., Finlay, A. Y., Burden, A. D., Kirby, B., Armendariz, Y., Williams, R., Hatchard, C., Khare, S. & Griffiths, C. E. M., 1 Jan 2019, In: British Journal of Dermatology.

Research output: Contribution to journal › Article › peer-review

Website | Journal

2018

Tissue engineering of human hair follicles using a biomimetic developmental approach

Authors:

Abaci, H. E., Coffman, A., Doucet, Y., Chen, J., Jacków, J., Wang, E., Guo, Z., Shin, J. U., Jahoda, C. A. & Christiano, A. M., 13 Dec 2018, In: Nature Communications. 9, 1, 11 p., 5301.

Research output: Contribution to journal › Article › peer-review

Website | Journal

An immunologically relevant rodent model demonstrates safety of therapy using a tumour-specific IgE

Authors:

Josephs, D. H., Nakamura, M., Bax, H. J., Dodev, T. S., Muirhead, G., Saul, L., Karagiannis, P., Ilieva, K. M., Crescioli, S., Gazinska, P., Woodman, N., Lomardelli, C., Kareemaghay, S., Selkirk, C., Lentfer, H., Barton, C., Canevari, S., Figini, M., Downes, N. & Dombrowicz, D. & 8 others, Corrigan, C. J., Nestle, F. O., Jones, P. S., Gould, H. J., Blower, P. J., Tsoka, S., Spicer, J. F. & Karagiannis, S. N., 1 Dec 2018, In: Allergy. 73, 12, p. 2328-2341 14 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Research Techniques Made Simple: Transepidermal Water Loss Measurement as a Research Tool

Authors:

Alexander, H., Brown, S., Danby, S. & Flohr, C., Nov 2018, In: Journal of Investigative Dermatology. 138, 11, p. 2295-2300.e1

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Spatiotemporal segregation of human marginal zone and memory B cell populations in lymphoid tissue

Authors:

Zhao, Y., Uduman, M., Siu, J., Tull, T. J., Sanderson, J., Wu, Y.-C. B., Zhou, J. Q., Petrov, N., Ellis, R. J., Todd, S. K., Chavele, K.-M., Guesdon, W. W. J., Vossenkamper, A., Jassem, W., D’Cruz, D., Fear, D. J., John, S., Scheel-Toellner, D., hopkins, C. & Moreno, E. & 6 others, Woodman, N., Ciccarelli, F. D., Heck, S., Kleinstein, S., Bemark, M. & Spencer, J. M., 21 Sept 2018, In: Nature Communications. 9, 1, 15 p., 3857.

Research output: Contribution to journal › Article › peer-review

Website | Journal

A small population, randomised, placebo-controlled trial to determine the efficacy of anakinra in the treatment of pustular psoriasis: Study protocol for the APRICOT trial

Authors:

Cornelius, V., Wilson, R., Cro, S., Barker, J., Burden, D., Griffiths, C. E. M., Lachmann, H., McAteer, H., Reynolds, N., Pink, A., Warren, R. B., Capon, F. & Smith, C., 29 Aug 2018, In: Trials. 19, 1, 465.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Effects of systemic immunosuppressive therapies for moderate-to-severe eczema in children and adults

Authors:

Küster, D., Spuls, P. I., Flohr, C., Smith, C., Hooft, L., Deckert, S., Schwennesen, T., Roekevisch, E. & Schmitt, J., 22 Aug 2018, In: Cochrane Database of Systematic Reviews. 2018, 8, CD011939.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Subcutaneous methotrexate in patients with moderate-to-severe psoriasis: a critical appraisal

Authors:

Tsakok, T., Jabbar-Lopez, Z. K. & Smith, C. H., Jul 2018, In: British Journal of Dermatology. 179, 1, p. 50-53 4 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Aldara-induced dermatitis is associated with development of liver fibrosis in mice

Authors:

Maybury, C. M., Di Meglio, P. & Smith, C. H., Jul 2018, In: British Journal of Dermatology. 179, 1, p. 9-10 2 p.

Research output: Contribution to journal › Comment/debate › peer-review

Website | Journal

537 Predicting response to ustekinumab in patients with psoriasis: A multicentre prospective observational cohort study: International Investigative Dermatology (IID) 2018 Meeting Abstract SupplementInternational Investigative Dermatology (IID) 2018

Authors:

Tsakok, T. & Smith, C., May 2018, In: Journal of Investigative Dermatology. 138, 5, Supplement, p. S91

Research output: Contribution to journal › Meeting Abstract › peer-review

Website | Journal

Chondroitin sulfate proteoglycan 4 and its potential as an antibody immunotherapy target across different tumor types

Authors:

Ilieva, K. M., Cheung, A., Mele, S., Chiaruttini, G., Crescioli, S., Griffin, M., Nakamura, M., Spicer, J. F., Tsoka, S., Lacy, K. E., Tutt, A. N. J. & Karagiannis, S. N., 10 Jan 2018, In: Frontiers in Immunology. 8, JAN, p. 1911 15 p., 1911.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Atopic dermatitis: the skin barrier and beyond

Authors:

Tsakok, T., Woolf, R., Smith, C. H., Weidinger, S. & Flohr, C., 1 Jan 2018, (Accepted/In press) In: British Journal of Dermatology.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Exposure to biological therapies during conception and pregnancy: a systematic review

Authors:

Pottinger, E., Woolf, R. T., Exton, L. S., Burden, A. D., Nelson-Piercy, C. & Smith, C. H., Jan 2018, In: British Journal of Dermatology. 178, 1, p. 95-102 8 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

2017

Next generation human skin constructs as advanced tools for drug development

Authors:

Abaci, H. E., Guo, Z., Doucet, Y., Jacków, J. & Christiano, A., 1 Nov 2017, In: Experimental Biology and Medicine. 242, 17, p. 1657-1668 12 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

An analysis of IL-36 signature genes and individuals with IL1RL2 knockout mutations validates IL-36 as a psoriasis therapeutic target

Authors:

Mahil, S. K., Catapano, M., Di Meglio, P., Dand, N., Ahlfors, H., Carr, I. M., Smith, C. H., Trembath, R. C., Peakman, M., Wright, J., Ciccarelli, F. D., Barker, J. N. & Capon, F., 11 Oct 2017, In: Science Translational Medicine. 9, 411, eaan2514.

Research output: Contribution to journal › Article › peer-review

Website | Journal

LB969 Preliminary validation of the IL-36 receptor as a target in psoriasis treatment

Authors:

Mahil, S., Peakman, M., Trembath, R., Wright, J., Barker, J. & Capon, F., 20 Sept 2017, (E-pub ahead of print) In: Journal of Investigative Dermatology. 137, 10, p. B7

Research output: Contribution to journal › Article › peer-review

Website | Journal

203 Preliminary therapeutic target validation of the IL-36 receptor in psoriasis: ESDR 2017 Annual Meeting47th Annual ESDR Meeting

Authors:

Mahil, S. K., Peakman, M., Trembath, R., Wright, J., Barker, J. & Capon, F., 8 Sept 2017, (E-pub ahead of print) In: Journal of Investigative Dermatology. 137, 10, Supplement 2, p. S227

Research output: Contribution to journal › Article › peer-review

Website | Journal

BRAF inhibitors: resistance and the promise of combination treatments for melanoma

Authors:

Griffin, M., Scotto, D., Josephs, D. H., Mele, S., Crescioli, S., Bax, H. J., Pellizzari, G., Wynne, M. D., Nakamura, M., Hoffmann, R. M., Ilieva, K. M., Cheung, A., Spicer, J. F., Papa, S., Lacy, K. E. & Karagiannis, S. N., 2017, In: Oncotarget. 8, 44, p. 78174-78192 19 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Immunopathogenesis of psoriasis

Authors:

Di Meglio, P. & Nestle, F., 2017, Clinical and Basic Immunodermatology: Second Edition,. p. 373–395

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Website | Journal

2016

AP1S3 mutations cause skin autoinflammation by disrupting keratinocyte autophagy and up-regulating IL-36 production

Authors:

Mahil, S. K., Twelves, S., Farkas, K., Setta-Kaffetzi, N., Burden, A. D., Gach, J. E., Irvine, A. D., Képíró, L., Mockenhaupt, M., Oon, H. H., Pinner, J., Ranki, A., Seyger, M. M., Soler-Palacin, P., Storan, E. R., Tan, E. S., Valeyrie-Allanore, L., Young, H. S., Trembath, R. C. & Choon, S.-E. & 6 others, Szell, M., Bata-Csorgo, Z., Smith, C. H., Di Meglio, P., Barker, J. N. & Capon, F., 30 Nov 2016, In: Journal of Investigative Dermatology. 136, 11, p. 2251–2259

Research output: Contribution to journal › Article › peer-review

Website | Journal

AP1S3 mutations cause cutaneous autoinflammation by disrupting autophagy and up-regulating IL-36 production in keratinocytes

Authors:

Mahil, S. K., Setta-Kaffetzi, N., Trembath, R., Smith, C. H., Di Meglio, P., Barker, J. & Capon, F., Sept 2016, In: Journal of Investigative Dermatology. 136, 9, Supplement 2, p. S208 274 .

Research output: Contribution to journal › Meeting abstract › peer-review

Website | Journal

Targeting CD8⁺ T cells prevents psoriasis development

Authors:

Di Meglio, P., Villanova, F., Navarini, A. A., Mylonas, A., Tosi, I., Nestle, F. O. & Conrad, C., 31 Jul 2016, In: Journal of Allergy and Clinical Immunology. 138, 1, p. 274-276.e6

Research output: Contribution to journal › Letter › peer-review

Website | Journal

Gene-Corrected Fibroblast Therapy for Recessive Dystrophic Epidermolysis Bullosa using a Self-Inactivating COL7A1 Retroviral Vector

Authors:

Jacków, J., Titeux, M., Portier, S., Charbonnier, S., Ganier, C., Gaucher, S. & Hovnanian, A., 1 Jul 2016, In: Journal of Investigative Dermatology. 136, 7, p. 1346-1354 9 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Candidate driver genes involved in genome maintenance and DNA repair in Sézary syndrome

Authors:

Woollard, W. J., Pullabhatla, V., Lorenc, A., Patel, V. M., Butler, R. M., Bayega, A., Begum, N., Bakr, F., Dedhia, K., Fisher, J., Aguilar-Duran, S., Flanagan, C., Ghasemi, A. A., Hoffmann, R. M., Castillo-Mosquera, N., Nuttall, E. A., Paul, A., Roberts, C. A., Solomonidis, E. G. & Tarrant, R. & 8 others, Yoxall, A., Beyers, C. Z., Ferreira, S., Tosi, I., Simpson, M. A., de Rinaldis, E., Mitchell, T. J. & Whittaker, S. J., 30 Jun 2016, In: Blood. 127, 26, p. 3387-97 11 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Collagen XVII Shedding Suppresses Re-Epithelialization by Directing Keratinocyte Migration and Dampening mTOR Signaling

Authors:

Jacków, J., Löffek, S., Nyström, A., Bruckner-Tuderman, L. & Franzke, C. W., 1 May 2016, In: Journal of Investigative Dermatology. 136, 5, p. 1031-1041 11 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Prevention of food allergy

Authors:

du Toit, G., Tsakok, T., Lack, S. & Lack, G., Apr 2016, In: Journal of Allergy and Clinical Immunology. 137, 4, p. 998-1010 13 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Does atopic dermatitis cause food allergy? A systematic review

Authors:

Tsakok, T., Marrs, T., Mohsin, M., Baron, S., du Toit, G., Till, S. & Flohr, C., Apr 2016, In: Journal of Allergy and Clinical Immunology. 137, 4, p. 1071-1078 8 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Propranolol in the treatment of infantile haemangiomas: Lessons from the European Propranolol in the Treatment of Complicated Haemangiomas (PITCH) Taskforce survey

Authors:

Wedgeworth, E., Glover, M., Irvine, A. D., Neri, I., Baselga, E., Clayton, T. H., Beattie, P. E., Bjerre, J. V., Burrows, N. P., Foelster-Holst, R., Hedelund, L., Hernandez-Martin, A., Audrain, H., Bhate, K., Brown, S. J., Baryschpolec, S., Darne, S., Durack, A., Dvorakova, V. & Gach, J. & 30 others, Goldstraw, N., Goodyear, H., Grabczynska, S., Greenblatt, D., Halpern, J., Hearn, R. M. R., Hoey, S., Hughes, B., Jayaraj, R., Johansson, E. K., Lam, M., Leech, S., O'Regan, G. M., Morrison, D., Porter, W., Ramesh, R., Schill, T., Shaw, L., Taylor, A. E. M., Taylor, R., Thomson, J., Tiffin, P., Tsakok, M., Janmohamed, S. R., Laguda, B., McPherson, T., Oranje, A. P., Patrizi, A., Ravenscroft, J. C. & Flohr, C., 1 Mar 2016, In: British Journal of Dermatology. 174, 3, p. 594-601 8 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Evaluation of immunophenotypic and molecular biomarkers for Sézary syndrome using standard operating procedures: multicenter study of 59 cases

Authors:

Boonk, S. E., Zoutman, W. H., Marie-Cardine, A., van der Fits, L., Out-Luiting, J. J., Mitchell, T. J., Tosi, I., Morris, S. L., Moriarty, B., Booken, N., Felcht, M., Quaglino, P., Ponti, R., Barberio, E., Ram-Wolff, C., Jäntti, K., Ranki, A., Bernengo, M. G., Klemke, C.-D. & Bensussan, A. & 6 others, Michel, L., Whittaker, S., Bagot, M., Tensen, C. P., Willemze, R. & Vermeer, M. H., 28 Feb 2016, (E-pub ahead of print) In: Journal of Investigative Dermatology.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Independent Loss of Methylthioadenosine Phosphorylase (MTAP) in Primary Cutaneous T-Cell Lymphoma

Authors:

Woollard, W. J., Kalaivani, N. P., Jones, C. L., Roper, C., Tung, L., Lee, J. J., Thomas, B. R., Tosi, I., Ferreira, S., Beyers, C. Z., Mckenzie, R. C. T., Butler, R. M., Lorenc, A., Whittaker, S. J. & Mitchell, T. J., 9 Feb 2016, (Accepted/In press) In: Journal of Investigative Dermatology. 136, 6, p. 1238-1246

Research output: Contribution to journal › Article › peer-review

Website | Journal

Measurement properties of quality of life measurement instruments for infants, children and adolescents with eczema: Protocol for a systematic review

Authors:

Heinl, D., Prinsen, C. A. C., Drucker, A. M., Ofenloch, R., Humphreys, R., Sach, T., Flohr, C. & Apfelbacher, C., 9 Feb 2016, In: Systematic Reviews. 5, 1, 25.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Correction: Are Treatments More Effective than Placebos? A Systematic Review and Meta-Analysis

Authors:

Howick, J., Friedemann, C., Tsakok, M., Watson, R., Tsakok, T., Thomas, J., Perera, R., Fleming, S. & Heneghan, C., 2016, In: PLoS ONE. 11, 1, p. e0147354

Research output: Contribution to journal › Article › peer-review

Website | Journal

Generation of a Functional Non-Shedding Collagen XVII Mouse Model: Relevance of Collagen XVII Shedding in Wound Healing

Authors:

Jacków, J., Schlosser, A., Sormunen, R., Nyström, A., Sitaru, C., Tasanen, K., Bruckner-Tuderman, L. & Franzke, C. W., 2016, In: Journal of Investigative Dermatology. 136, 2, p. 516-525 10 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Psoriasis, Cutaneous Lupus Erithematosus and Immunobiology of the Skin

Authors:

Di Meglio, P., 2016, Encyclopedia of Immunobiology.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Website | Journal

2015

The Role of Yeast in Atopic Dermatitis Revisited: a Critical Appraisal

Authors:

Tsakok, T., Schulenburg, H., Smith, C., Till, S. & Flohr, C., 1 Dec 2015, In: Current Dermatology Reports. 4, 4, p. 228-240 13 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Update on psoriasis immunopathogenesis and targeted immunotherapy

Authors:

Mahil, S. K., Capon, F. & Barker, J. N., 16 Nov 2015, In: Seminars In Immunopathology. 38, 1, p. 11-27

Research output: Contribution to journal › Article › peer-review

Website | Journal

A persistent vulval ulcer

Authors:

Maybury, C. M., Pink, A. & Lewis, F., 16 Oct 2015, In: BMJ (Clinical research ed.). 351, h5421.

Research output: Contribution to journal › Article › peer-review

Website | Journal

PHACE syndrome misdiagnosed as a port-wine stain

Authors:

Thomson, J., Greig, A., Lloyd, C., Morrison, D. & Flohr, C., 15 Jul 2015, In: BMJ case reports. 2015

Research output: Contribution to journal › Article › peer-review

Website | Journal

Immunoglobulin E and allergy: Antibodies in immune inflammation and treatment

Authors:

Karagiannis, S. N., Karagiannis, P., Debra, D. H., Saul, L., Gilbert, A. E., Upton, N. & Gould, H. J., 26 May 2015, Antibodies for Infectious Diseases. WILEY-BLACKWELL, p. 75-102 28 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Website | Journal

Deletion of the major bullous pemphigoid epitope region of collagen XVII induces blistering, autoimmunization, and itching in mice

Authors:

Hurskainen, T., Kokkonen, N., Sormunen, R., Jackow, J., Löffek, S., Soininen, R., Franzke, C. W., Bruckner-Tuderman, L. & Tasanen, K., 22 May 2015, In: Journal of Investigative Dermatology. 135, 5, p. 1303-1310 8 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

The Genetic Architecture of the Human Immune System: A Bioresource for Autoimmunity and Disease Pathogenesis

Authors:

Roederer, M., Quaye, L., Mangino, M., Beddall, M. H., Mahnke, Y., Chattopadhyay, P., Tosi, I., Napolitano, L., Terranova Barberio, M., Menni, C., Villanova, F., Di Meglio, P., Spector, T. D. & Nestle, F. O., 9 Apr 2015, In: Cell. 161, 2, p. 387-403 17 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Eczema and indoor environment: lessons from the International Study of Asthma and Allergies in Childhood (ISAAC) Phase 2

Authors:

ISAAC Phase 2 Study Group, 26 Feb 2015, In: Lancet. 385 Suppl 1, p. S99

Research output: Contribution to journal › Article › peer-review

Website | Journal

Lineage tracing mediated by Cre-Recombinase activity

Authors:

Vorhagen, S., Jackow, J., Mohor, S. G., Tanghe, G., Tanrikulu, L., Skazik-Vogt, C. & Tellkamp, F., 1 Jan 2015, In: Journal of Investigative Dermatology. 135, 1, p. e28

Research output: Contribution to journal › Article › peer-review

Website | Journal

Targeted Therapies and Biomarkers for Personalized Treatment of Psoriasis

Authors:

Di Meglio, P., 2015, Personalized Treatment Options in Dermatology.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Website | Journal

Genetics of Psoriasis

Authors:

Mahil, S. K., Capon, F. & Barker, J. N., Jan 2015, In: Dermatologic clinics. 33, 1, p. 1-11 11 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

2014

Overweight/obesity and respiratory and allergic disease in children: International study of asthma and allergies in childhood (ISAAC) phase two

Authors:

ISAAC Phase Two Steering Group, 4 Dec 2014, In: PLoS ONE. 9, 12, e113996.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Third time coming HOME: Not just EASI

Authors:

Flohr, C., 1 Dec 2014, In: British Journal of Dermatology. 171, 6, p. 1287-1288 2 p.

Research output: Contribution to journal › Comment/debate › peer-review

Website | Journal

IL-22 fate reporter reveals origin and control of IL-22 production in homeostasis and infection

Authors:

Ahlfors, H., Morrison, P. J., Duarte, J. H., Li, Y., Biro, J., Tolaini, M., Di Meglio, P., Potocnik, A. J. & Stockinger, B., 1 Nov 2014, In: Journal of Immunology. 193, 9, p. 4602-4613

Research output: Contribution to journal › Article › peer-review

Website | Journal

Improvement in quality of life impairment followed by relapse with 6-monthly periodic administration of omalizumab for severe treatment-refractory chronic urticaria and urticarial vasculitis

Authors:

Kai, A. C., Flohr, C. & Grattan, C. E., Jul 2014, In: Clinical and Experimental Dermatology. 39, 5, p. 651-652 2 p.

Research output: Contribution to journal › Letter › peer-review

Website | Journal

Activation of the aryl hydrocarbon receptor dampens the severity of inflammatory skin conditions

Authors:

Di Meglio, P., Duarte, J. H., Ahlfors, H., Owens, N. D. L., Li, Y., Villanova, F., Tosi, I., Hirota, K., Nestle, F. O., Mrowietz, U., Gilchrist, M. J. & Stockinger, B., 19 Jun 2014, In: Immunity. 40, 6, p. 989-1001 13 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris

Authors:

Navarini, A. A., Simpson, M. A., Weale, M., Knight, J., Carlavan, I., Reiniche, P., Burden, D. A., Layton, A., Bataille, V., Allen, M., Pleass, R., Pink, A., Creamer, D., English, J., Munn, S., Walton, S., Willis, C., Deret, S., Voegel, J. J. & Spector, T. & 4 others, Smith, C. H., Trembath, R. C., Barker, J. N. & Acne Genetic Study Grp, 13 Jun 2014, In: Nature Communications. 5, 1, 6 p., 4020.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Birthweight and the risk of atopic diseases: The ISAAC Phase III study

Authors:

Mitchell, E. A., Clayton, T., García-Marcos, L., Pearce, N., Foliaki, S., Wong, G., Aït-Khaled, N., Anderson, H. R., Asher, M. I., Beasley, R., Björkstén, B., Brunekreef, B., Crane, J., Ellwood, P., Flohr, C., Forastiere, F., Keil, U., Lai, C. K. W., Mallol, J. & Montefort, S. & 30 others, Odhiambo, J., Robertson, C. F., Stewart, A. W., Strachan, D., von Mutius, E., Weiland, S. K., Weinmayr, G., Williams, H., Ellwood, E., de Freitas Souza, L., Rennie, D., Aguilar, P., Amarales, L., Aristizábal, G., Cepeda, A. M., Riikjärv, M. A., Zsigmond, G., Mantri, S. N., Pherwani, A. V., Rego, S., Salvi, S., Sharma, S. K., Sukumaran, T. U., Suresh Babu, P. S., Kartasasmita, C. B., Moyes, C., Nunes, C., Lee, H. B., Huang, J. L. & Kao, C. C., 1 May 2014, In: Pediatric Allergy and Immunology. 25, 3, p. 264-270 7 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Characterization of Innate Lymphoid Cells in Human Skin and Blood Demonstrates Increase of NKp44+ILC3 in Psoriasis

Authors:

Villanova, F., Flutter, B., Tosi, I., Grys, K., Sreeneebus, H., Perera, G., Chapman, A., Smith, C., Di Meglio, P. & Nestle, F., 1 Apr 2014, In: Journal of Investigative Dermatology. 134, 4, p. 984-991 8 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Transmembrane collagen XVII modulates integrin dependent keratinocyte migration via PI3K/Rac1 signaling

Authors:

Löffek, S., Hurskainen, T., Jackow, J., Sigloch, F. C., Schilling, O., Tasanen, K., Bruckner-Tuderman, L. & Franzke, C. W., 5 Feb 2014, In: PLoS ONE. 9, 2, e87263.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Pediatric urticaria

Authors:

Tsakok, T., Du Toit, G. & Flohr, C., Feb 2014, In: IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA. 34, 1, p. 117-139 23 p.

Research output: Contribution to journal › Literature review › peer-review

Website | Journal

The association between atopic dermatitis and food allergy in adults

Authors:

Manam, S., Tsakok, T., Till, S. & Flohr, C., 1 Jan 2014, In: Current Opinion in Allergy and Clinical Immunology. 14, 5, p. 423-429 7 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

The aryl hydrocarbon receptor: multitasking in the immune system.

Authors:

Di Meglio, P., 2014, In: Annual Review of Immunology.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Psoriasis

Authors:

Di Meglio, P., Villanova, F. & Nestle, F., 2014, In: Cold Spring Harbor perspectives in medicine. 4, 8

Research output: Contribution to journal › Review article › peer-review

Website | Journal

New blisters in a patient treated for Stevens-Johnson syndrome/toxic epidermal necrolysis

Authors:

Mahil, S. K., Martin, B., Creamer, D. & Smith, C. H., Jan 2014, In: Clinical and Experimental Dermatology. 39, 1, p. 63-65 3 p.

Research output: Contribution to journal › Letter › peer-review

Website | Journal

2013

Following in the footsteps of David Barker: The association between extreme prematurity and atopic dermatitis risk

Authors:

Flohr, C., Dec 2013, In: British Journal of Dermatology. 169, 6, p. 1175-1176 2 p.

Research output: Contribution to journal › Comment/debate › peer-review

Website | Journal

Does early life exposure to antibiotics increase the risk of eczema? A systematic review

Authors:

Tsakok, T., McKeever, T. M., Yeo, L. & Flohr, C., Nov 2013, In: British Journal of Dermatology. 169, 5, p. 983-991 9 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

The IL23R A/Gln381 Allele Promotes IL-23 Unresponsiveness in Human Memory T-Helper 17 Cells and Impairs Th17 Responses in Psoriasis Patients

Authors:

Di Meglio, P., Villanova, F., Napolitano, L., Tosi, I., Terranova Barberio, M., Mak, R. K., Nutland, S., Smith, C. H., Barker, J. N. W. N., Todd, J. A. & Nestle, F. O., Oct 2013, In: Journal of Investigative Dermatology. 133, 10, p. 2381-2389 9 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Psoriasis and risk of cardiovascular disease: Case report and discussion

Authors:

Maybury, C. & Smith, C. H., Sept 2013, In: Heart and Metabolism. 60, p. 30-33 4 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

A cutaneous lymphoma international prognostic index (CLIPi) for mycosis fungoides and Sezary syndrome

Authors:

Benton, E. C., Crichton, S., Talpur, R., Agar, N. S., Fields, P. A., Wedgeworth, E., Mitchell, T. J., Cox, M., Ferreira, S., Liu, P., Robson, A., Calonje, E., Stefanato, C. M., Wilkins, B., Scarisbrick, J., Wain, E. M., Child, F., Morris, S., Duvic, M. & Whittaker, S. J., Sept 2013, In: European Journal of Cancer. 49, 13, p. 2859-2868 10 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Systemic therapies for severe atopic dermatitis in children and adults

Authors:

Flohr, C. & Irvine, A. D., Sept 2013, In: Journal of Allergy and Clinical Immunology. 132, 3, p. 774-774.e6

Research output: Contribution to journal › Review article › peer-review

Website | Journal

An In-Depth Characterization of the Major Psoriasis Susceptibility Locus Identifies Candidate Susceptibility Alleles within an HLA-C Enhancer Element

Authors:

Clop, A., Bertoni, A., West, S. S., Simpson, M. A., Pullabhatla, V., Tonda, R., Hundhausen, C., Di Meglio, P., De Jong, P., Hayday, A. C., Nestle, F. O., Barker, J. N., Bell, R. J. A., Capon, F. & Trembath, R., 19 Aug 2013, In: PL o S One . 8, 8, 8 p., e71690.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Eczema and allergic sensitisation – What is the link?

Authors:

Eczema and allergic sensitisation - What is the link?

Flohr, C., Aug 2013, In: Current Allergy and Clinical Immunology. 26, 3, p. 131-135 5 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Gene expression changes with age in skin, adipose tissue, blood and brain

Authors:

Glass, D., Vinuela, A., Davies, M. N., Ramasamy, A., Parts, L., Knowles, D., Brown, A. A., Hedman, A. K., Small, K. S., Buil, A., Grundberg, E., Nica, A. C., Di Meglio, P., Nestle, F. O., Ryten, M., Durbin, R., McCarthy, M. I., Deloukas, P., Dermitzakis, E. T. & Weale, M. E. & 4 others, Bataille, V., Spector, T. D., UK Brain Expression Consortium & MuTHER Consortium, 26 Jul 2013, In: GENOME BIOLOGY. 14, 7, p. N/A 12 p., R75.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Integration of lyoplate based flow cytometry and computational analysis for standardized immunological biomarker discovery

Authors:

Villanova, F., Di Meglio, P., Inokuma, M., Aghaeepour, N., Perucha, E., Mollon, J., Nomura, L., Hernandez Fuentes, M., Cope, A., Prevost, A. T., Heck, S., Maino, V., Lord, G., Brinkman, R. R. & Nestle, F. O., 3 Jul 2013, In: PLoS ONE. 8, 7, 8 p., e65485.

Research output: Contribution to journal › Article › peer-review

Website | Journal

IgG4 subclass antibodies impair antitumor immunity in melanoma

Authors:

Karagiannis, P., Gilbert, A. E., Josephs, D. H., Ali, N., Dodev, T., Saul, L., Correa, I., Roberts, L., Beddowes, E., Koers, A., Hobbs, C., Ferreira, S., Geh, J., Healy, C., Harries, M., Acland, K. M., Blower, P. J., Mitchell, T., Fear, D. J. & Spicer, J. F. & 3 others, Lacy, K. E., Nestle, F. O. & Karagiannis, S. N., 1 Apr 2013, In: Journal of Clinical Investigation. 123, 4, p. 1457–1474 18 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Biomarkers in psoriasis and psoriatic arthritis

Authors:

Villanova, F., Di Meglio, P. & Nestle, F. O., Apr 2013, In: Annals of the Rheumatic Diseases. 72, s2, p. 104-110 7 p., N/A.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Demyelination during tumour necrosis factor antagonist therapy for psoriasis: a case report and review of the literature

Authors:

Mahil, S. K., Andrews, T. C., Brierley, C., Barker, J. N. & Smith, C. H., Feb 2013, In: JOURNAL OF DERMATOLOGICAL TREATMENT. 24, 1, p. 38-49 12 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Are treatments more effective than placebos? A systematic review and meta-analysis

Authors:

Howick, J., Friedemann, C., Tsakok, M., Watson, R., Tsakok, T., Thomas, J., Perera, R., Fleming, S. & Heneghan, C., 2013, In: PLoS ONE. 8, 5, p. e62599

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Aquagenic urticaria in twins

Authors:

Kai, A. C. & Flohr, C., 2013, In: World Allergy Organization Journal. 6, 1, 2.

Research output: Contribution to journal › Article › peer-review

Website | Journal

CD8 T cells and IFN-γ emerge as critical players for psoriasis in a novel model of mouse psoriasiform skin inflammation

Authors:

Di Meglio, P. & Duarte, J., 2013, In: Journal of Investigative Dermatology. 133, (4), p. 871-974

Research output: Contribution to journal › Comment/debate › peer-review

Website | Journal

Differential Influences of the Aryl Hydrocarbon Receptor on Th17 Mediated Responses in vitro and in vivo

Authors:

Duarte, J. H., Di Meglio, P., Hirota, K., Ahlfors, H. & Stockinger, B., 2013, In: PLOS One. 8, 11, e79819.

Research output: Contribution to journal › Article › peer-review

Website | Journal

2012

Helicobacter pylori induces in-vivo expansion of human regulatory T cells through stimulating interleukin-1β production by dendritic cells

Authors:

Mitchell, P. J., Afzali, B., Fazekasova, H., Chen, D., Ali, N., Powell, N., Lord, G. M., Lechler, R. I. & Lombardi, G., Dec 2012, In: Clinical and Experimental Immunology. 170, 3, p. 300-309 10 p., N/A.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Mutations in the gamma-Secretase Genes NCSTN, PSENEN, and PSEN1 Underlie Rare Forms of Hidradenitis Suppurativa (Acne Inversa)

Authors:

Pink, A. E., Simpson, M. A., Desai, N., Dafou, D., Hills, A., Mortimer, P. S., Smith, C. H., Trembath, R. C. & Barker, J. N. W., Oct 2012, In: Journal of Investigative Dermatology. 132, 10, p. 2459-2461 3 p.

Research output: Contribution to journal › Letter › peer-review

Website | Journal

Mapping cis- and trans-regulatory effects across multiple tissues in twins

Authors:

Grundberg, E., Small, K. S., Hedman, A. K., Nica, A. C., Buil, A., Keildson, S., Bell, J. T., Yang, T.-P., Meduri, E., Barrett, A., Nisbett, J., Sekowska, M., Wilk, A., Shin, S.-Y., Glass, D., Travers, M., Min, J. L., Ring, S., Ho, K. & Thorleifsson, G. & 31 others, Kong, A., Thorsteindottir, U., Ainali, C., Dimas, A. S., Hassanali, N., Ingle, C., Knowles, D., Krestyaninova, M., Lowe, C. E., Di Meglio, P., Montgomery, S. B., Parts, L., Potter, S., Surdulescu, G., Tsaprouni, L., Tsoka, S., Bataille, V., Durbin, R., Nestle, F. O., O'Rahilly, S., Soranzo, N., Lindgren, C. M., Zondervan, K. T., Ahmadi, K. R., Schadt, E. E., Stefansson, K., Smith, G. D., McCarthy, M. I., Deloukas, P., Spector, T. D. & Multiple Tissue Human Expression R, Oct 2012, In: Nature Genetics. 44, 10, p. 1084-1089 8 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

A novel skin-resident vitamin D3 inducible CD141(+) human dendritic cell playing a critical role in tissue homeostasis and immunoregulation

Authors:

Ali, N., Chu, C., Karagiannis, P., Di Meglio, P., Barinaga, G., Grys, K., Karagiannis, S. N., Peakman, M., Lombardi, G. & Nestle, F. O., Sept 2012, In: Journal of Investigative Dermatology. 132, p. S14-S14 1 p.

Research output: Contribution to journal › Meeting abstract › peer-review

Website | Journal

Coiled coils ensure the physiological ectodomain shedding of collagen XVII

Authors:

Nishie, W., Jackow, J., Hofmann, S. C., Franzke, C. W. & Bruckner-Tuderman, L., 24 Aug 2012, In: Journal of Biological Chemistry. 287, 35, p. 29940-29948 9 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Regulation of T-Plastin Expression by Promoter Hypomethylation in Primary Cutaneous T-Cell Lymphoma

Authors:

Jones, C. L., Ferreira, S., McKenzie, R. C. T., Tosi, I., Caesar, J. A., Bagot, M., Whittaker, S. J. & Mitchell, T. J., Aug 2012, In: Journal of Investigative Dermatology. 132, 8, p. 2042-2049 8 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Promoter methylation of argininosuccinate synthetase-1 sensitises lymphomas to arginine deiminase treatment, autophagy and caspase-dependent apoptosis

Authors:

Delage, B., Luong, P., Maharaj, L., O'Riain, C., Syed, N., Crook, T., Hatzimichael, E., Papoudou-Bai, A., Mitchell, T. J., Whittaker, S. J., Cerio, R., Gribben, J., Lemoine, N., Bomalaski, J., Li, C.-F., Joel, S., Fitzgibbon, J., Chen, L.-T. & Szlosarek, P. W., Jul 2012, In: Cell Death & Disease. 3, 7, p. - 9 p., e342.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Resident CD141 (BDCA3)(+) dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation

Authors:

Chu, C.-C., Ali, N., Karagiannis, P., Di Meglio, P., Skowera, A., Napolitano, L., Barinaga, G., Grys, K., Sharif-Paghaleh, E., Karagiannis, S. N., Peakman, M., Lombardi, G. & Nestle, F. O., 7 May 2012, In: Journal of Experimental Medicine. 209, 5, p. 935-945 11 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

The challenges of replicating the methodology between Phases I and III of the ISAAC programme

Authors:

Ellwood, P., Asher, M. I., Stewart, A. W., Aït-Khaled, N., Mallol, J., Strachan, D., Anderson, H. R., Beasley, R., Björkstén, B., Brunekreef, B., Crane, J., Flohr, C., Foliaki, S., Forastiere, F., García-Marcos, L., Keil, U., Lai, C. K. W., Mitchell, E. A., Montefort, S. & Odhiambo, J. & 7 others, Pearce, N., Robertson, C. F., Von Mutius, E., Weiland, S. K., Weinmayr, G., Williams, H. & Wong, G., 1 May 2012, In: INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE. 16, 5, p. 687-693 7 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Allele-Specific Cytokine Responses at the HLA-C Locus: Implications for Psoriasis

Authors:

Hundhausen, C., Bertoni, A., Mak, R. K., Botti, E., Di Meglio, P., Clop, A., Laggner, U., Chimenti, S., Hayday, A. C., Barker, J. N., Trembath, R. C., Capon, F. & Nestle, F. O., Mar 2012, In: Journal of Investigative Dermatology. 132, 3, p. 635 - 641 7 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Constitutive activation of STAT3 in Sezary syndrome is independent of SHP-1

Authors:

McKenzie, R. C. T., Jones, C. L., Tosi, I., Caesar, J. A., Whittaker, S. J. & Mitchell, T. J., Feb 2012, In: Leukemia. 26, 2, p. 323 - 331 9 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Reticulate hyperpigmentation of the vulva

Authors:

Tsakok, T., Sheth, N., Suchak, R., Calonje, E. & Neill, S., Jan 2012, In: Archives of Dermatology. 148, 1, p. 113-8 6 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

A solitary lesion on the palmar aspect of the right middle finger of an 11 year old boy.

Authors:

Boyce, A. E., Dadzie, O. E. & Flohr, C., 2012, In: Pediatric dermatology. 29, 1, p. 111-112 2 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Psoriasis

Authors:

Perera, G., Di Meglio, P. & Nestle, F., 2012, In: Annual Review of Pathology: Mechanisms of Disease. 7, p. 385-422

Research output: Contribution to journal › Review article › peer-review

Website | Journal

2011

Immunological biomarker discovery in psoriasis using an advanced flow cytometry platform

Authors:

Villanova, F., Di Meglio, P., Inokuma, M., Heck, S., Perucha, E., Fuentes, M. H., Maino, S., Lord, G. & Nestle, F. O., Dec 2011, In: British Journal of Dermatology. 165, 6, p. E39-E40 2 p.

Research output: Contribution to journal › Meeting abstract › peer-review

Website | Journal

Global analysis of breast feeding and risk of symptoms of asthma, rhinoconjunctivitis and eczema in 6-7 year old children: ISAAC Phase Three

Authors:

Björkstén, B., Aït-Khaled, N., Asher, M. I., Clayton, T. O., Robertson, C., Anderson, H. R., Beasley, R., Brunekreef, B., Crane, J., Ellwood, P., Flohr, C., Foliaki, S., Forastiere, F., García-Marcos, L., Keil, U., Lai, C. K. W., Mallol, J., Mitchell, E. A., Odhiambo, J. & Montefort, S. & 30 others, Pearce, N., Stewart, A. W., Strachan, D., von Mutius, E., Weiland, S. K., Williams, H., Wong, G., Howitt, M. E., Weyler, J., de Freitas Souza, L., Rennie, D., Aguilar, P., Aristizábal, G., Cepeda, A. M., Riikjärv, M. A., sigmond, G. Z., Awasthi, S., Bhave, S., Hanumante, N. M., Jain, K. C., Mantri, S. N., Joshi, M. K., Rego, S., Salvi, S., Sharma, S. K., Moyes, C., Nunes, C., Lee, H. B., Huang, J. L. & Kao, C. C., 1 Nov 2011, In: Allergologia et Immunopathologia. 39, 6, p. 318-325 8 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Mutations in IL36RN/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis

Authors:

Onoufriadis, A., Simpson, M. A., Pink, A. E., Di Meglio, P., Smith, C. H., Pullabhatla, V., Knight, J., Spain, S. L., Nestle, F. O., Burden, A. D., Capon, F., Trembath, R. C. & Barker, J. N., 9 Sept 2011, In: American Journal of Human Genetics. 89, 3, p. 432-437 6 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Allergic Contact Dermatitis

Authors:

Flohr, C. & English, J. S. C., 24 May 2011, Harper's Textbook of Pediatric Dermatology: Third Edition. WILEY-BLACKWELL, Vol. 1. p. 1-13 13 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Website | Journal

Epidemiology of Atopic Dermatitis

Authors:

Flohr, C. & Williams, H. C. G., 24 May 2011, Harper's Textbook of Pediatric Dermatology: Third Edition. WILEY-BLACKWELL, Vol. 1. p. 1-15 15 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Website | Journal

Incidence of cancer in the context of atopic dermatitis

Authors:

Wedgeworth, E., Powell, A. M. & Flohr, C., Apr 2011, In: British Journal of Dermatology. 164, 4, p. 896-897 2 p.

Research output: Contribution to journal › Letter › peer-review

Website | Journal

Acetaminophen use and risk of asthma, rhinoconjunctivitis, and eczema in adolescents: International study of asthma and allergies in childhood phase three

Authors:

Beasley, R. W., Clayton, T. O., Crane, J., Lai, C. K. W., Montefort, S. R., Von Mutius, E., Stewart, A. W., Aït-Khaled, N., Anderson, H. R., Asher, M. I., Björkstén, B., Brunekreef, B., Ellwood, P., Flohr, C., Forastiere, F., García-Marcos, L., Foliaki, S., Keil, U., Mallol, J. & Robertson, C. F. & 9 others, Mitchell, E. A., Odhiambo, J., Pearce, N., Shah, J., Strachan, D., Weiland, S. K., Weinmayr, G., Williams, H. & Wong, G., 15 Jan 2011, In: American Journal of Respiratory and Critical Care Medicine. 183, 2, p. 171-178 8 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

2010

Survival Outcomes and Prognostic Factors in Mycosis Fungoides/Sezary Syndrome: Validation of the Revised International Society for Cutaneous Lymphomas/European Organisation for Research and Treatment of Cancer Staging Proposal

Authors:

Agar, N. S., Wedgeworth, E., Crichton, S., Mitchell, T. J., Cox, M., Ferreira, S., Robson, A., Calonje, E., Stefanato, C. M., Wain, E. M., Wilkins, B., Fields, P., Dean, A., Webb, K., Scarisbrick, J., Morris, S. & Whittaker, S. J., 1 Nov 2010, In: Journal of Clinical Oncology. 28, 31, p. 4730 - 4739 10 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

A model for harmonizing flow cytometry in clinical trials

Authors:

Maecker, H. T., McCoy, J. P., Amos, M., Elliott, J., Gaigalas, A., Wang, L., Aranda, R., Banchereau, J., Boshoff, C., Braun, J., Korin, Y., Reed, E., Cho, J., Hafler, D., Davis, M., Fathman, C. G., Robinson, W., Denny, T., Weinhold, K. & Desai, B. & 25 others, Diamond, B., Gregersen, P., Di Meglio, P., DiMeglio, P., Nestle, F. O., Nestle, F., Peakman, M., Villanova, F., Villnova, F., Ferbas, J., Field, E., Kantor, A., Kawabata, T., Komocsar, W., Lotze, M., Nepom, J., Ochs, H., O'Lone, R., Phippard, D., Plevy, S., Rich, S., Roederer, M., Rotrosen, D., Yeh, J.-H. & FOCIS Human Immunophenotyping Consortium, Nov 2010, In: Nature Immunology. 11, 11, p. 975-8 4 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Ectodomain shedding generates neoepitopes on collagen XVII, the major autoantigen for bullous pemphigoid

Authors:

Nishie, W., Lamer, S., Schlosser, A., Licarete, E., Franzke, C. W., Hofmann, S. C., Jackow, J., Sitaru, C. & Bruckner-Tuderman, L., 15 Oct 2010, In: Journal of Immunology. 185, 8, p. 4938-4947 10 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Eczema: An evidence based update. Report from the 9th Nottingham evidence based update meeting, 13 May 2010, Loughborough, U.K.

Authors:

Flohr, C. & Powell, A. M., Sept 2010, In: British Journal of Dermatology. 163, 3, p. 456-457 2 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

MicroRNA expression in Sezary syndrome: identification, function, and diagnostic potential

Authors:

Ballabio, E., Mitchell, T., van Kester, M. S., Taylor, S., Dunlop, H. M., Chi, J., Tosi, I., Vermeer, M. H., Tramonti, D., Saunders, N. J., Boultwood, J., Wainscoat, J. S., Pezzella, F., Whittaker, S. J., Tensen, C. P., Hatton, C. S. R. & Lawrie, C. H., 19 Aug 2010, In: Blood. 116, 7, p. 1105 - 1113 9 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

The impact of the method of consent on response rates in the ISAAC time trends study

Authors:

Ellwood, P., Asher, M. I., Stewart, A. W., Aït-Khaled, N., Anderson, H. R., Beasley, R., Björkstén, B., Brunekreef, B., Crane, J., Flohr, C., Foliaki, S., Forastiere, F., García-Marcos, L., Keil, U., Lai, C. K. W., Mallol, J., Mitchell, E. A., Montefort, S., Odhiambo, J. & Pearce, N. & 30 others, Robertson, C. F., Strachan, D., von Mutius, E., Weiland, S. K., Weinmayr, G., Williams, H., Wong, G., Clayton, T. O., Benhabylès, B., Esamai, F. O., Ng'ang'a, L., Bouayad, Z., Onadeko, B. O., Zar, H. J., Jerray, M., Chen, Y. Z., Zhong, N. S., Lau, Y. L., Kartasasmita, C. B., Odajima, H., Teh, K. H., de Bruyne, J., Lee, H. B., Huang, J. L., Sharma, S. K., Fischer, G. B., Redding, G. J., Moyes, C., Nunes, C. & Lee, B., Aug 2010, In: INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE. 14, 8, p. 1059-1065 7 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Updates from the British Association of Dermatologists 89th Annual Meeting, 7-10 July 2009, Glasgow, U.K.

Authors:

Alexandroff, A. B., Flohr, C. & Johnston, G. A., Jul 2010, In: British Journal of Dermatology. 163, 1, p. 27-37 11 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Effect of diet on asthma and allergic sensitisation in the international study on allergies and asthma in childhood (ISAAC) phase two

Authors:

Nagel, G., Weinmayr, G., Kleiner, A., Garcia-Marcos, L., Strachan, D. P., Aït-Khaled, N., Anderson, H. R., Flohr, C., Williams, H., Forastiere, F., Asher, I., Ellwood, P., Stewart, A., Mitchell, E., Crane, J., Pearce, N., Beasley, R., Björkstén, B., Brunekreef, B. & Foliaki, S. & 9 others, Keil, U., Von Mutius, E., Weiland, S. K., Lai, C. K. W., Wong, G. W. K., Mallol, J., Montefort, S., Odhiambo, J. & Robertson, C., 1 Jun 2010, In: Thorax. 65, 6, p. 516-522 7 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Downregulation of Fas Gene Expression in Sezary Syndrome Is Associated with Promoter Hypermethylation

Authors:

Jones, C. L., Wain, E. M., Chu, C.-C., Tosi, I., Foster, R., McKenzie, R. C. T., Whittaker, S. J. & Mitchell, T. J., Apr 2010, In: Journal of Investigative Dermatology. 130, 4, p. 1116 - 1125 10 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Cutaneous Lymphoma International Prognostic Index (CLIPI)

Authors:

Benton, E. C., Crichton, S., Agar, N. S., Fields, P., Wedgeworth, E., Mitchell, T. J., Cox, M., Ferreira, S., Robson, A. M., Calonje, E., Stefanato, C. M., Wain, E. M., Wilkins, B., Dean, A., Webb, K., Scarisbrick, J., Morris, S. & Whittaker, S. J., 2010, In: British Journal of Dermatology. 163, p. 11 - 11 1 p.

Research output: Contribution to journal › Meeting abstract

Website | Journal

Merocel^® nasal packing with airway: A method to help secure full-thickness skin grafts on the nasal tip

Authors:

Flohr, C., Lee, K. K. & Varma, S., Jan 2010, In: British Journal of Dermatology. 162, 1, p. 209-210 2 p.

Research output: Contribution to journal › Letter › peer-review

Website | Journal

2009

Global variations in prevalence of eczema symptoms in children from ISAAC Phase Three

Authors:

ISAAC Phase Three Study Group, 1 Dec 2009, In: Journal of Allergy and Clinical Immunology. 124, 6

Research output: Contribution to journal › Article › peer-review

Website | Journal

Cutaneous tuberculosis due to Mycobacterium bovis lasting for more than 60 years

Authors:

Flohr, C., Khan, M., Leach, I. H., Johnston, I. D. A. & English, J. S. C., Dec 2009, In: Clinical and Experimental Dermatology. 34, 8, p. 921-923 3 p.

Research output: Contribution to journal › Letter › peer-review

Website | Journal

How well do questionnaires perform compared with physical examination in detecting flexural eczema? Findings from the International Study of Asthma and Allergies in Childhood (ISAAC) Phase Two

Authors:

Flohr, C., Weinmayr, G., Weiland, S. K., Addo-Yobo, E., Annesi-Maesano, I., Björkstén, B., Bråbäck, L., Büchele, G., Chico, M., Cooper, P., Clausen, M., Sharif, N. E., Gimeno, A. M., Mathur, R. S., von Mutius, E., Suarez-Varela, M. M., Pearce, N., Svabe, V., Wong, G. W. K. & Yu, M. & 30 others, Zhong, N. S., Williams, H. C., Büchele, G., Genuneit, J., Kleiner, A., Nagel, G., Weinmayr, G., Priftanji, A., Shkurti, A., Simenati, J., Grabocka, E., Shyti, K., Agolli, S., Gurakuqi, A., Stein, R. T., Urrutia de Pereira, M., Jones, M. H., Pitrez, P. M., Cooper, P. J., Chico, M., Chen, Y. Z., Zhong, N. S., Lai, C., Forastiere, F., Serra, M. G., Crane, J., Anderson, H. R., Flohr, C., Forastiere, F. & Stewart, A., 1 Oct 2009, In: British Journal of Dermatology. 161, 4, p. 846-853 8 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Translation of questions: The International Study of Asthma and Allergies in Childhood (ISAAC) experience

Authors:

Ellwood, P., Williams, H., Aït-Khaled, N., Björkstén, B., Robertson, C., Anderson, H. R., Asher, M. I., Beasley, R., Brunekreef, B., Crane, J., Flohr, C., Foliaki, S., Forastiere, F., García-Marcos, L., Keil, U., Lai, C. K. W., Mallol, J., Mitchell, E. A., Montefort, S. & Odhiambo, J. & 8 others, Pearce, N., Robertson, C. F., Stewart, A. W., Strachan, D., Von Mutius, E., Weiland, S. K., Weinmayr, G. & Wong, G., Sept 2009, In: INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE. 13, 9, p. 1174-1182 9 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Global variation in the prevalence and severity of asthma symptoms: Phase Three of the International Study of Asthma and Allergies in Childhood (ISAAC)

Authors:

Lai, C. K. W., Beasley, R., Crane, J., Foliaki, S., Shah, J., Weiland, S., Aït-Khaled, N., Anderson, H. R., Asher, M. I., Björksten, B., Brunekreef, B., Ellwood, P., Flohr, C., Foliaki, S., Forastiere, F., García-Marcos, L., Keil, U., Lai, C. K. W., Mallol, J. & Mitchell, E. A. & 12 others, Montefort, S., Odhiambo, J., Pearce, N., Robertson, C. F., Shah, J., Stewart, A. W., Strachan, D., Von Mutius, E., Weiland, S. K., Weinmayr, G., Williams, H. & Wong, G., Jun 2009, In: Thorax. 64, 6, p. 476-483 8 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

The role of allergic sensitisation in childhood eczema: an epidemiologist’s perspective

Authors:

The role of allergic sensitisation in childhood eczema: an epidemiologist's perspective

Flohr, C., Apr 2009, In: Allergologia et Immunopathologia. 37, 2, p. 89-92 4 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Recurrent Novel Regions of Uniparental Disomy and Homozygous Deletions in Mycosis Fungoides Identified Using High Resolution Single Nucleotide Polymorphism Analysis.

Authors:

Mohamedali, A. M., Mitch-ell, T. J., Ferreira, S., Guinn, B. A., Ireland, R. M., Whittaker, S. J. & Mufti, G. J., 2009, In: Blood. 114, 22, p. 1037 - 1037 1 p.

Research output: Contribution to journal › Meeting abstract

Website | Journal

Survival outcomes and prognostic factors in mycosis fungoides/Sezary syndrome: a comparison of the AJCC staging system with the revised ISCL/EORTC proposal

Authors:

Agar, N., Wedgeworth, E., Scarisbrick, J., Morris, S., Cox, M., Robson, A., Calonje, E., Stefanato, C., Mitchell, T., Ferreira, S., Webb, K. & Whittaker, S., 2009, In: British Journal of Dermatology. 161, p. 1 - 1 1 p.

Research output: Contribution to journal › Meeting abstract

Website | Journal

Evaluation of HDAC inhibitors on Stat3 activation status in primary cutaneous T-cell lymphoma

Authors:

McKenzie, R. C. T., Jones, C. L., Tosi, I., Whittaker, S. J. & Mitchell, T. J., 2009, In: British Journal of Dermatology. 160, 4, p. 926 - 926 1 p.

Research output: Contribution to journal › Meeting abstract

Website | Journal

Do helminth parasites protect against atopy and allergic disease?

Authors:

Flohr, C., Quinnell, R. J. & Britton, J., Jan 2009, In: Clinical and Experimental Allergy. 39, 1, p. 20-32 13 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Peri-stomal ulceration with nicorandil

Authors:

Donaldson, J. F., Flohr, C. & English, J. S., 2009, In: Colorectal Disease. 11, 4, p. 426-427 2 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

2008

Compositae allergy in three children with hand dermatitis

Authors:

Flohr, C., Ravenscroft, J. & English, J., Dec 2008, In: Contact Dermatitis. 59, 6, p. 370-371 2 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Topical silver sulfadiazine-induced systemic argyria in a patient with severe generalized dystrophic epidermolysis bullosa

Authors:

Flohr, C., Heague, J., Leach, I. & English, J., Sept 2008, In: British Journal of Dermatology. 159, 3, p. 740-741 2 p.

Research output: Contribution to journal › Letter › peer-review

Website | Journal

International variation in prevalence of flexural eczema and atopic sensitization. Results from phase two of the International Study of Asthma and Allergies in Childhood (ISAAC Phase Two)

Authors:

Internationale variabilität in der prävalenz von neurodermitis und einfluss der atopischen sensibilisierung - Ergebnisse der Phase zwei der International Study of Asthma and Allergies in Childhood (ISAAC II)

Translated title of the contribution: Kleiner, A., Flohr, C., Weiland, S., Weinmayr, G., Büchele, G., Rzehak, P., Björkstén, B., Bråbäck, L., Brunekreef, B., Clausen, M., Cookson, W., Von Mutius, E., Strachan, D. & Williams, H., Feb 2008, In: Allergo Journal. 17, 1, p. 79-81 3 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

2007

The role of furry pets in eczema: A systematic review

Authors:

Langan, S. M., Flohr, C. & Williams, H. C., Dec 2007, In: Archives of Dermatology. 143, 12, p. 1570-1577 8 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Low efficacy of mebendazole against hookworm in Vietnam: Two randomized controlled trials

Authors:

Flohr, C., Tuyen, L. N., Lewis, S., Minh, T. T., Campbell, J., Britton, J., Williams, H., Hien, T. T., Farrar, J. & Quinnell, R. J., Apr 2007, In: American Journal of Tropical Medicine and Hygiene. 76, 4, p. 732-736 5 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

2006

Poor sanitation and helminth infection protect against skin sensitization in Vietnamese children: A cross-sectional study

Authors:

Flohr, C., Tuyen, L. N., Lewis, S., Quinnell, R., Minh, T. T., Liem, H. T., Campbell, J., Pritchard, D., Hien, T. T., Farrar, J., Williams, H. & Britton, J., Dec 2006, In: Journal of Allergy and Clinical Immunology. 118, 6, p. 1305-1311 7 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

How epidemiology has challenged 3 prevailing concepts about atopic dermatitis

Authors:

Williams, H. & Flohr, C., Jul 2006, In: Journal of Allergy and Clinical Immunology. 118, 1, p. 209-213 5 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

2005

Signal transducer and activator of transcription (STAT) signalling and T-cell lymphomas

Authors:

Mitchell, T. J. & John, S., Mar 2005, In: Immunology. 114, 3, p. 301 - 312 12 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Fine mapping of chromosome 10q deletions in mycosis fungoides and Sezary syndrome: Identification of two discrete regions of deletion at 10q23.33-24.1 and 10q24.33-25.1

Authors:

Wain, E. M., Mitchell, T. J., Russell-Jones, R. & Whittaker, S. J., Feb 2005, In: Genes Chromosomes and Cancer. 42, 2, p. 184 - 192 9 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Atopic dermatitis and the ‘hygiene hypothesis’: Too clean to be true?

Authors:

Atopic dermatitis and the 'hygiene hypothesis': Too clean to be true?

Flohr, C., Pascoe, D. & Williams, H. C., Feb 2005, In: British Journal of Dermatology. 152, 2, p. 202-216 15 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Dysregulation of Stat5 Isoform expresion in Sezary Syndrome

Authors:

Dysregulation of Stat5 Isoform expresion in Sezary Syndrome

John, S., Hendry, S., Mitchell, T. J. & Whittaker, S. J., 2005, International Symposium on the Biology and Immunology of Cutaneous Lymphoma. Unknown Publisher, p. 48 - 48 1 p.

Research output: Chapter in Book/Report/Conference proceeding › Conference paper

Website | Journal

2004

Erratum: Evidence based management of atopic eczema (Archives of Diseases in Childhood (2004) 89 (ep35-ep39))

Authors:

Flohr, C. & Williams, H. C., Dec 2004, In: Archives of Disease in Childhood: Education and Practice Edition. 89, 3, p. ep75

Research output: Contribution to journal › Comment/debate › peer-review

Website | Journal

Evidence based management of atopic eczema

Authors:

Flohr, C. & Williams, H. C., Oct 2004, In: Archives of Disease in Childhood: Education and Practice Edition. 89, 2, p. ep35-ep39

Research output: Contribution to journal › Review article › peer-review

Website | Journal

How atopic is atopic dermatitis?

Authors:

Flohr, C., Johansson, S. G. O., Wahlgren, C. F. & Williams, H., Jul 2004, In: Journal of Allergy and Clinical Immunology. 114, 1, p. 150-158 9 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

A randomized cross-over study to compare PUVA and extracorporeal photopheresis in the treatment of plaque stage (T2) mycosis fungoides

Authors:

Child, F. J., Mitchell, T. J., Whittaker, S. J., Scarisbrick, J. J., Seed, P. T. & Russell-Jones, R., May 2004, In: Clinical and Experimental Dermatology. 29, 3, p. 231 - 236 6 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Prevalence and associated factors of atopic dermatitis symptoms in rural and urban Ethiopia

Authors:

Yemaneberhan, H., Flohr, C., Lewis, S. A., Bekele, Z., Parry, E., Williams, H. C., Britton, J. & Venn, A., May 2004, In: Clinical and Experimental Allergy. 34, 5, p. 779-785 7 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

2003

Dysregulated expression of COOH-terminally truncated Stat5 and loss of IL2-inducible Stat5-dependent gene expression in Sezary Syndrome

Authors:

Mitchell, T. J., Whittaker, S. J. & John, S., 15 Dec 2003, In: Cancer Research. 63, 24, p. 9048 - 9054 7 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Microsatellite instability is associated with hypermethylation of the hMLH1 gene and reduced gene expression in mycosis fungoides

Authors:

Scarisbrick, J. J., Mitchell, T. J., Calonje, E., Orchard, G., Russell-Jones, R. & Whittaker, S. J., 1 Oct 2003, In: Journal of Investigative Dermatology. 121, 4, p. 894 - 901 8 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Dirt, worms and atopic dermatitis

Authors:

Flohr, C., 1 May 2003, In: British Journal of Dermatology. 148, 5, p. 871-877 7 p.

Research output: Contribution to journal › Review article › peer-review

Website | Journal

Quantitative MRI detects abnormalities in relatives of patients with epilepsy and malformations of cortical development

Authors:

Merschhemke, M., Mitchell, T., Free, S., Hammers, A., Kinton, L., Siddiqui, A., Stevens, J., Kendall, B., Meencke, H. & Duncan, J., Mar 2003, In: NeuroImage. 18, 3, p. 642-649 8 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Blastic natural killer cell and extranodal natural killer cell-like T-cell lymphoma presenting in the skin: report of six cases from the UK

Authors:

Child, F. J., Mitchell, T. J., Whittaker, S. J., Calonje, E., Spittle, M., Crocker, J. & Russell-Jones, R., 1 Mar 2003, In: British Journal of Dermatology. 148, 3, p. 507 - 515 9 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

Abnormal Stat5 expression in Sezary syndrome

Authors:

Mitchell, T. J., Whittaker, S. M., Ayday, A. C. & John, S., 2003, In: British Journal of Dermatology. 148, 4, p. 854 - 854 1 p., O22.

Research output: Contribution to journal › Meeting abstract

Website | Journal

2002

Molecular cytogenetic analysis of cutaneous T-cell lymphomas: identification of common genetic alterations in Sezary syndrome and mycosis fungoides

Authors:

Mao, X., Lillington, D., Scarisbrick, J. J., Mitchell, T., Czepulkowski, B., Russell-Jones, R., Young, B. & Whittaker, S. J., 2002, In: British Journal of Dermatology. 147, 3, p. 464 - 475 12 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal

1996

The Plague Fighter: Wu Lien-teh and the beginning of the Chinese public health system

Authors:

Flohr, C., 1 Jul 1996, In: ANNALS OF SCIENCE. 53, 4, p. 361-380 20 p.

Research output: Contribution to journal › Article › peer-review

Website | Journal