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Hyperinflammatory repolarisation of ovarian cancer patient macrophages by anti-tumour IgE antibody, MOv18, restricts an immunosuppressive macrophage:Treg cell interaction

by admin | Apr 10, 2025

Hyperinflammatory repolarisation of ovarian cancer patient macrophages by anti-tumour IgE antibody, MOv18, restricts an immunosuppressive macrophage:Treg cell interactionOsborn, G., Lopez-Abente Muroz, J., Adams, R., Laddach, R., Grandits, M., Bax, H., Chauhan, J.,...

Porous Silicon Nanoneedles Efficiently Deliver Adenine Base Editor to Correct a Recurrent Pathogenic COL7A1 Variant in Recessive Dystrophic Epidermolysis Bullosa

by admin | Mar 12, 2025

Porous Silicon Nanoneedles Efficiently Deliver Adenine Base Editor to Correct a Recurrent Pathogenic COL7A1 Variant in Recessive Dystrophic Epidermolysis BullosaMustfa, S. A., Dimitrievska, M., Wang, C., Gu, C., Sun, N., Romańczuk, K., Karpinski, P., Łaczmański, Ł.,...

Non-Allergic Urticarial Skin Reactions Associated With MOv18 IgE, a First-In-Class IgE Antibody Recognising Folate Receptor Alpha

by admin | Mar 6, 2025

Non-Allergic Urticarial Skin Reactions Associated With MOv18 IgE, a First-In-Class IgE Antibody Recognising Folate Receptor AlphaStavraka, C., Chauhan, J., Crescioli, S., McSweeney, S. M., Pope, A., Gillett, C., Di Meo, A., Prassas, I., Laddach, R., Stoker, K.,...

Folate receptor alpha for cancer therapy: an antibody and antibody-drug conjugate target coming of age

by admin | Mar 6, 2025

Folate receptor alpha for cancer therapy: an antibody and antibody-drug conjugate target coming of ageLiu, Y., Chen, S., Evan, T., Esapa, B., Chenoweth, A., Cheung, A. & Karagiannis, S. N., 6 Mar 2025, In: Mabs. 17, 1, p. 2470309 17 p., 2470309.Research output:...

GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets

by admin | Feb 28, 2025

GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targetsDand, N., Stuart, P. E., Bowes, J., Ellinghaus, D., Nititham, J., Saklatvala, J. R., Teder-Laving, M., Thomas, L. F., Traks, T., Uebe, S.,...
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